76 research outputs found

    CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

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    Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

    FIGURE 2 in An unusual new basal iguanodont (Dinosauria: Ornithopoda) from the Lower Cretaceous of Teruel, Spain

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    FIGURE 2. Quadrate of Proa valdearinnoensis. Left quadrate of AR-1-2012 (holotype) in lateral (A), tracing in lateral (B), medial (C), dorsal (D), and ventral (E) views. Abbreviations: bf, bone fragment; dc, dorsal condyle; lcs, lateral condylar surface; mw, medial wing; qjn, quadratojugal notch; vc, ventral condyle. Scale bars equal 10 cm.Published as part of <i>Mcdonald, Andrew T., Espílez, Eduardo, Mampel, Luis, Kirkland, James I. & Alcalá, Luis, 2012, An unusual new basal iguanodont (Dinosauria: Ornithopoda) from the Lower Cretaceous of Teruel, Spain, pp. 61-76 in Zootaxa 3595 (1)</i> on page 65, DOI: 10.11646/zootaxa.3595.1.3, <a href="http://zenodo.org/record/10096874">http://zenodo.org/record/10096874</a&gt

    FIGURE 10 in An unusual new basal iguanodont (Dinosauria: Ornithopoda) from the Lower Cretaceous of Teruel, Spain

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    FIGURE 10. Adams consensus of 24,460 MPTs showing the phylogenetic relationships of Proa valdearinnoensis (highlighted in blue). Placement of clade names at certain nodes follows the definitions of Sereno (2005).Published as part of <i>Mcdonald, Andrew T., Espílez, Eduardo, Mampel, Luis, Kirkland, James I. & Alcalá, Luis, 2012, An unusual new basal iguanodont (Dinosauria: Ornithopoda) from the Lower Cretaceous of Teruel, Spain, pp. 61-76 in Zootaxa 3595 (1)</i> on page 73, DOI: 10.11646/zootaxa.3595.1.3, <a href="http://zenodo.org/record/10096874">http://zenodo.org/record/10096874</a&gt

    FIGURE 7 in An unusual new basal iguanodont (Dinosauria: Ornithopoda) from the Lower Cretaceous of Teruel, Spain

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    FIGURE 7. Dentition of Proa valdearinnoensis. Maxillary teeth in left maxilla of AR-1-2012 (holotype) in labial (A) view. Dentary teeth in right dentary AR-1-2013 (holotype) in lingual (B) view. Abbreviations: dar, distal accessory ridge; mar, mesial accessory ridge; prr, primary ridge; sr, secondary ridge. Scale bars equal 1 cm.Published as part of <i>Mcdonald, Andrew T., Espílez, Eduardo, Mampel, Luis, Kirkland, James I. & Alcalá, Luis, 2012, An unusual new basal iguanodont (Dinosauria: Ornithopoda) from the Lower Cretaceous of Teruel, Spain, pp. 61-76 in Zootaxa 3595 (1)</i> on page 70, DOI: 10.11646/zootaxa.3595.1.3, <a href="http://zenodo.org/record/10096874">http://zenodo.org/record/10096874</a&gt
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