INFLUENCE OF FEEDING NORMS ON BIOLOGICAL INDICATORS AND ON THE PHENOTYPIC VARIABILITY OF MULBERRY SILKWORM UNDER THE CONDITIONS OF THE REPUBLIC OF AZERBAIJA

In comparison with the normal conditions of feeding, in the conditions of abundant feeding, the mean values of the studied biological indicators (except for the silkiness of wet cocoons) are exaggerated, and phenotypic variability decreases. With poor feeding, the average values of the indicators decrease, and the phenotypic variability increases. During the study, the minimum increase and decrease of the average value of all symptoms and the coefficient of variation in the Mayak-3 breed were revealed; the greatest increase and decrease of indicators were marked in the Yashar breed; and in the Ganja-6 breed, growth and deposition of indicators were at an average level. Thus, the hereditary tolerance to the environmental impact of the feeding factor is strong in the Mayak-3 breed, moderate in the Ganja-6 breed, and weak in the Yashar breed

MATHEMATICAL AND STATISTICAL PC MODELLING OF INTRASYSTEM AND INTERCOMPONENT INTERRELATION BETWEEN PHYSICAL AND GEOGRAPHICAL COMPLEXES FOR THE RATIONAL NATURE MANAGEMENT (ON THE EXAMPLE OF THE LESSER CAUCASUS WITHIN AZERBAIJAN’S BORDERS)

Authors of this paper describe the methodological mathematical-statistical model, internal interdependent element of the geosystem, and the geosystem component in order to ensure rational nature management

Prospects and threats for developing organic agriculture: The example of Azerbaijan

The article's purpose is to evaluate empirical evidence of the main threats to organic agriculture formation and provide the argumentation of its development prospects in Azerbaijan's current conditions. Questioning of agricultural business owners identified threats and prospects for developing organic agriculture in Azerbaijan. The opportunities and threats for developing organic agriculture are determined and differentiated by groups of entrepreneurs doing business in traditional/organic agriculture. Based on the results of the clustering of the agricultural enterprises depending on the level, the priority of threats, and prospects for development, the strategies for developing organic agriculture in Azerbaijan have been determined:  educational strategy of financial accessibility, innovative growth, and infrastructure development

NATIONAL GEOINFORMATION SYSTEM OF NATURAL RESOURCES OF THE AZERBAIJAN REPUBLIC FOR ENVIRONMETNTAL PROTECTION

One of the main problems of natural and economic planning of the natural and anthropogenic geosystem is the detection of urgent characteristics of various types of geosystems through application of the complex of methods of modern mathematics such as, theory of information (information-statistical methods and etc.); theory of mathematic statics (methods of factoral, regressional, correlational, component and dispersional analysis etc.); theory of linear and matrix algebra (methods of linear programming, simplex methods and etc.); theory of distribution (methods of parameters estimation of universe etc.); theory of random functions (methods of definition of probability of events etc.); theory of graphs; theory of catastrophes etc

Care of patients with inborn errors of immunity in thirty J Project countries between 2004 and 2021

IntroductionThe J Project (JP) physician education and clinical research collaboration program was started in 2004 and includes by now 32 countries mostly in Eastern and Central Europe (ECE). Until the end of 2021, 344 inborn errors of immunity (IEI)-focused meetings were organized by the JP to raise awareness and facilitate the diagnosis and treatment of patients with IEI.ResultsIn this study, meeting profiles and major diagnostic and treatment parameters were studied. JP center leaders reported patients’ data from 30 countries representing a total population of 506 567 565. Two countries reported patients from JP centers (Konya, Turkey and Cairo University, Egypt). Diagnostic criteria were based on the 2020 update of classification by the IUIS Expert Committee on IEI. The number of JP meetings increased from 6 per year in 2004 and 2005 to 44 and 63 in 2020 and 2021, respectively. The cumulative number of meetings per country varied from 1 to 59 in various countries reflecting partly but not entirely the population of the respective countries. Altogether, 24,879 patients were reported giving an average prevalence of 4.9. Most of the patients had predominantly antibody deficiency (46,32%) followed by patients with combined immunodeficiencies (14.3%). The percentages of patients with bone marrow failure and phenocopies of IEI were less than 1 each. The number of patients was remarkably higher that those reported to the ESID Registry in 13 countries. Immunoglobulin (IgG) substitution was provided to 7,572 patients (5,693 intravenously) and 1,480 patients received hematopoietic stem cell therapy (HSCT). Searching for basic diagnostic parameters revealed the availability of immunochemistry and flow cytometry in 27 and 28 countries, respectively, and targeted gene sequencing and new generation sequencing was available in 21 and 18 countries. The number of IEI centers and experts in the field were 260 and 690, respectively. We found high correlation between the number of IEI centers and patients treated with intravenous IgG (IVIG) (correlation coefficient, cc, 0,916) and with those who were treated with HSCT (cc, 0,905). Similar correlation was found when the number of experts was compared with those treated with HSCT. However, the number of patients treated with subcutaneous Ig (SCIG) only slightly correlated with the number of experts (cc, 0,489) and no correlation was found between the number of centers and patients on SCIG (cc, 0,174).Conclusions1) this is the first study describing major diagnostic and treatment parameters of IEI care in countries of the JP; 2) the data suggest that the JP had tremendous impact on the development of IEI care in ECE; 3) our data help to define major future targets of JP activity in various countries; 4) we suggest that the number of IEI centers and IEI experts closely correlate to the most important treatment parameters; 5) we propose that specialist education among medical professionals plays pivotal role in increasing levels of diagnostics and adequate care of this vulnerable and still highly neglected patient population; 6) this study also provides the basis for further analysis of more specific aspects of IEI care including genetic diagnostics, disease specific prevalence, newborn screening and professional collaboration in JP countries

Services design in academic libraries and its impact on university community

Purpose. The purpose of the paper is to study how service design is developed and implemented in academic libraries in order to meet the requirements of the university community in their educational, research and/or personal activities. Methodology. The author aims to bring clarification to modern concepts, such as design thinking principles, process and methods to make them more understandable for the readers, and describe planning stages of the services design in academic libraries. The paper was compiled based on related literature review, observations, and findings from case studies Findings. Detailed services design planning allows the libraries to foresee all possible difficulties and shortcomings of the planned library services, and thus sidestep these problems by considering all conditions in the initial stage. The primary goal of the services design activity in academic libraries is mostly connected to meeting library and information needs of the university community, and creating new library services for all situations (such as the current pandemic) that might be in great demand by library patrons, though they might not even realize it. Therefore, a special and in-depth study of the user behavior and feedback in certain library services is essential in terms of understanding patrons’ requirements, and developing more innovative user-centered services for them. Originality/value. The services design process and design thinking principles and methods are broadly discussed topics in modern librarianship, which make this paper competitive enough to analyze different points of views and find out one can be applicable in certain circumstances and/or environments. In this regard, the suggested tools and techniques can be practical for most young library specialists working in public services units of academic libraries

MATHEMATICAL AND STATISTICAL PC MODELING OF INTRASYSTEM AND INTERCOMPONENT INTERRELATION BETWEEN PHYSICAL AND GEOGRAPHICAL COMPLEXES IN ORDER TO ENSURE RATIONAL NATURE MANAGEMENT (ON THE EXAMPLE OF THE LESSER CAUCASUS WITHIN AZERBAIJAN BORDERS)

In the article we describe the methodology of mathematical-statistical modeling of internal interrelation of elements of the geosystem and intercomponents of the geosystyem in order to ensure rational nature management

The Novel Patient with BLNK Gene Type of Agammaglobulinemia

Background: Agammaglobulinemia (AGM) is a genetic immune system disorder in which the body could not produce antibodies. There are two types of this disease: X-linked AGM (XLA) and autosomal forms. X-linked agammaglobulinemia results from a mutation in the gene for Bruton’s tyrosine kinase (BTK), found on the X chromosome. Mutations in BTK result in lack of mature B-cells and immunoglobulins of all classes. There are 8 types of autosomal forms which are reflected in different defective genes. 7-year-old male patient at the age of 1 - 6, was encountered the recurrent broncho-pulmonary and gastro-intestinal infections, furunculosis and recurrent otitis. Also, because of the strain, pain and swelling on the 4th finger of the right hand it was suspected that the patient had rheumatoid arthritis. On immunological investigation, we have found out of absent of B lymphocyte. Level of IgG was 10 times less; IgA, IgM and IgE levels were 3 to 8 times less than the norm. Quantity of T-lymphocytes: absolute number of CD4+ lymphocytes increased, CD3+ and CD8+ lymphocytes were also high. Phagocyte activity in NBT, absolute number of NK cells and IRI index were 2 times lower than the norm. Genetically analysis has discovered the presence of abnormal homozygous BLNK gene