Assessing the risk of chemotherapy toxicity and hospital admission due to toxicity: A study of acute chemotherapy toxicity and related hospital admission in a large UK teaching hospital, based on proactive telephone assessment patients

Introduction: Acute chemotherapy toxicity is common and can have negative effects for the patient and health economy and hospitalisation can be necessitated. Aims: To identify the incidence of toxicity and admission, and predictors of toxicity occurrence, severity, hospitalisation and length of stay. Method: Data was obtained from a proactive telephone assessment of acute toxicity 24 hours after administration of a first cycle of chemotherapy to patients in a large UK NHS teaching hospital. Results: 1539 patients were studied and the overall incidence of toxicity was 35.6% (530 patients). Disease site and number of chemotherapy agents given were shown to predict toxicity, with breast and upper gastrointestinal cancers having a higher likelihood of toxicity. Disease was predictive of toxicity grade, with urology, gynaecology and lung cancer patients experiencing higher grades of toxicity than other tumour sites. The rate of hospital admission due to toxicity was 13.1% (203 patients) and median length of stay 3 days (1-28). The risk of admission had some risk factors in common with toxicity. Disease and the number of drugs in the regimen affected the risk of admission, with gynaecology, head and neck and lung cancer patients and patients who received 3 drugs having a higher likelihood of admission. Predictors in the subgroups of breast, colorectal and lung cancer patients did not differ greatly from the whole population and the number of drugs was shown to be a predictor of nausea, vomiting and fatigue when explored as secondary outcomes. Conclusion: The research partly addressed the main aim and highlighted areas where further research is required. Keyword

Laser Wire Scanner Compton Scattering Techniques for the Measurement of the Transverse Beam Size of Particle Beams at Future Linear Colliders

This archive summarizes a working paper and conference proceedings related to laser wire scanner development for the Future Linear Collider (FLC) in the years 2001 to 2006. In particular the design, setup and data taking for the laser wire experiments at PETRA II and CT2 are described. The material is focused on the activities undertaken by Royal Holloway University of London (RHUL).Comment: 61 page

Talk about the perfection of the System of Time Limit for Quotations in Civil Actions in China

“公正与效率”是新时代司法制度改革的主题。为实现公正与效率，1999年最高人民法院公布了《人民法院五年改革纲要》，进一步要求在民事诉讼中加强当事人的举证责任。2001年12月21日最高人民法院公布《关于民事诉讼证据的若干规定》，由此确立了我国举证时限制度，标志着我国“证据随时提出主义”向“证据适时提出主义”的转变。该规定强化了当事人的举证，对于实现民事审判公正与效率，完善我国民事诉讼制度具有重要而深远的意义。本文除引言和结语外，分为三章。本文第一章从举证时限制度的含义出发，分析制度的构成及价值，指出保障民事诉讼当事人诉讼权利平等与公正及提高诉讼效率是举证时限制度所要实现的目标和价值取向。同时，...“Equity and efficiency” are the themes of the judicial system restructuring in the new epoch. In order to realize the equity and efficiency, the Supreme Court issued 《the program for the court reformation in five years》 in 1999. It claimed to strengthen the onus probandi for the parties in the civil actions ulteriorly. The Supreme Court issued 《Some Provisions on the Evidences in Civil Action》on D...学位：法律硕士院系专业：法学院法律系_法律硕士(JM)学号：X20010807

Resolution of a High Performance Cavity Beam Positron Monitor System

International Linear Collider (ILC) interaction region beam sizes and component position stability requirements will be as small as a few nanometers. It is important to the ILC design effort to demonstrate that these tolerances can be achieved--ideally using beam-based stability measurements. It has been estimated that RF cavity beam position monitors (BPMs) could provide position measurement resolutions of less than one nanometer and could form the basis of the desired beam-based stability measurement. We have developed a high resolution RF cavity BPM system. A triplet of these BPMs has been installed in the extraction line of the KEK Accelerator Test Facility (ATF) for testing with its ultra-low emittance beam. A metrology system for the three BPMs was recently installed. This system employed optical encoders to measure each BPM's position and orientation relative to a zero-coefficient of thermal expansion carbon fiber frame and has demonstrated that the three BPMs behave as a rigid-body to less than 5 nm. To date, we have demonstrated a BPM resolution of less than 20 nm over a dynamic range of +/- 20 microns

Tracking studies of the Compact Linear Collider collimation system

A collimation system performance study includes several types of computations performed by different codes. Optics calculations are performed with codes such as MADX, tracking studies including additional effects such as wakefields, halo and tail generation, and dynamical machine alignment are done with codes such as PLACET, and energy deposition can be studied with BDSIM. More detailed studies of hadron production in the beam halo interaction with collimators are better performed with GEANT4 and FLUKA. A procedure has been developed that allows one to perform a single tracking study using several codes simultaneously. In this paper we study the performance of the Compact Linear Collider collimation system using such a procedure

ATF2 Proposal

ATF2 Group Accelerator Physic

Performance of a Nanometer Resolution Bpm System

International Linear Collider (ILC) interaction region beam sizes and component position stability requirements will be as small as a few nanometers. It is important to the ILC design effort to demonstrate that these tolerances can be achieved--ideally using beam-based stability measurements. It has been estimated that RF cavity beam position monitors (BPMs) could provide position measurement resolutions of less than one nanometer and could form the basis of the desired beam-based stability measurement. We have developed a high resolution RF cavity BPM system. A triplet of these BPMs has been installed in the extraction line of the KEK Accelerator Test Facility (ATF) for testing with its ultra-low emittance beam. The three BPMs are rigidly mounted inside an alignment frame on variable-length struts which allow movement in position and angle. We have developed novel methods for extracting the position and tilt information from the BPM signals including a calibration algorithm which is immune to beam jitter. To date, we have been able to demonstrate a resolution of approximately 20 nm over a dynamic range of +/- 20 microns. We report on the progress of these ongoing tests