Revue d'histoire du Bas-Saint-Laurent, vol. 12 (3-4)

Mot de l'éditeur -- Au micro de CJBR -- La grande histoire de CJBR -- Jules-A. Brillant et le poste CJBR -- Avec CJBR, un bon en avant pour le Bas St-Laurent -- CJBR, l'école -- L'annonceur: un éducateur populaire -- Sandy Burgess : le journaliste que j'ai connu -- "Ce pays qui est le mien" -- Un demi-siècle d'information: que de nouvelles! -- Journaliste de père en fils à CJBR -- Le théâtre à CJBR -- 50 ans de musique à CJBR, le château fort de la mélodie française -- Poésie, théâtre, jazz et originalité avec Michel Garneau -- Les "Chroniques du dimanche", l'âge d'or de la critique culturelle à CJBR -- "Si CJBR m'était conté..." -- L'évolution technologique, un élément-clef de l'histoire des 50 ans de radiodiffusion -- La publicité à CJBR, quarante ans de croissance -- Des pionnières à CJBR -- 1958-1972, des années enrichissantes -- De Trois-Pistoles à Rimouski -- Le sport et son enracinement dans le milieu régional -- "Debout c'est l'heure", c'est Jean Brisson qui sonne le réveil -- "Par une belle journée de tempête" -- Et on repart vers la centain

Bronchodilator Responsiveness and Reported Respiratory Symptoms in an Adult Population

<div><p>Background</p><p>The relationship between patient-reported symptoms and objective measures of lung function is poorly understood.</p> <p>Aim</p><p>To determine the association between responsiveness to bronchodilator and respiratory symptoms in random population samples.</p> <p>Methods</p><p>4669 people aged 40 years and older from 8 sites in Canada completed interviewer-administered respiratory questionnaires and performed spirometry before and after administration of 200 ug of inhaled salbutamol. The effect of anthropometric variables, smoking exposure and doctor-diagnosed asthma (DDA) on bronchodilator responsiveness in forced expiratory volume in 1 second (FEV₁) and in forced vital capacity (FVC) were evaluated. Multiple logistic regression was used to test for association between quintiles of increasing changes in FEV₁ and in FVC after bronchodilator and several respiratory symptoms.</p> <p>Results</p><p>Determinants of bronchodilator change in FEV₁ and FVC included age, DDA, smoking, respiratory drug use and female gender [p<0.005 to p<0.0001 ]. In subjects without doctor-diagnosed asthma or COPD, bronchodilator response in FEV₁ was associated with wheezing [p for trend<0.0001], while bronchodilator response for FVC was associated with breathlessness. [p for trend <0.0001].</p> <p>Conclusions</p><p>Bronchodilator responsiveness in FEV₁ or FVC are associated with different respiratory symptoms in the community. Both flow and volume bronchodilator responses are useful parameters which together can be predictive of both wheezing and breathlessness in the general population.</p> </div

A Canadian, Multicentre, Randomized Clinical Trial of Home-Based Pulmonary Rehabilitation in Copd: Rationale and Methods

BACKGROUND: Pulmonary rehabilitation remains largely underused. Self-monitored, home-based rehabilitation is a promising approach to improving the availability of pulmonary rehabilitation

Population demographics and risk factors of individual sites and for whole cohort.

§<p>Doctor Diagnosis of AO = presence of self reported prior diagnosis of either ever-asthma, or asthmatic bronchitis, or allergic bronchitis, or COPD, or emphysema, or chronic bronchitis. Data for Age, BMI, Packyears, and Spirometry results are expressed in mean(SD); All others are expressed as % of group(SE) and are weighted to the local population. BMI = Body-mass index;</p>†<p>% predicted values = maximum values/predicted values(NHANES)*100;</p>*<p>One-Way ANOVA, alpha = 0.05;</p>#<p>Chi-Square Test.</p>&<p>post bronchodilator responses: % change in FEV1 or FVC after bronchodilator relative to pre-bronchodilator value.</p

Determinants of bronchodilator responsiveness in forced expiratory volume in one second as % pre-bronchodilator value [%ΔFEV1i] –results from univariate and multivariate analyses of the whole cohort.

*<p>Standard estimates allow comparison between variables with different units. It is the expected change in bronchodilator response per 1 SD increase in the variable. After multivariate correction for confounding variables the ‘most powerful’ effect on BDRFEV1 is doctor diagnosis of current-asthma, followed by age, ever-smoking, use of respiratory drugs (any medication for breathing including nasal decongestant), and gender.These values are adjusted for all corivariates including site and for the proportion of Caucasian population in each site.</p

Logistic regression analysis of cohort without self-reported diagnosis of ever-asthma, COPD/Chronic bronchitis/Emphysema (n = 3508) showing risk [adjusted Odds ratio & 95% confidence intervals] of Symptoms with increasing post-bronchodilator change in forced expiratory volume in 1 sec % pre-bronchodilator value (%ΔFEV1i).

*<p>Variables for the first Quintile were used as the reference;</p><p>#Slope for trend was statistically different from the horizontal. Odds ratios and 95% CI adjusted for age, BMI, gender, usage of respiratory drugs (any medication for breathing including nasal decongestant), ever-smoking, site, and porpotion of Caucasian.</p

Logistic regression analysis of cohort without self-reported diagnosis of ever-asthma, COPD/Chronic bronchitis/Emphysema (n = 3378) showing risk [adjusted Odds ratio & 95% confidence intervals] of Symptoms with increasing post-bronchodilator change in forced vital capacity as % Pre-bronchodilator value (%ΔFVCi).

*<p>Variables for the first Quintile were used as the reference;</p><p>#Slope for trend was statistically different from the horizontal. Odds ratios and 95% CI adjusted for age, BMI, gender, usage of respiratory drugs (any medication for breathing including nasal decongestant), ever-smoking, site, and proportion of Caucasian.</p