Essays in International Economics: Decomposing Episodes of Large Growth in International Trade

My thesis consists of three chapters relating to topics in International Economics. In the first essay, I use bilateral trade data from Canada, Germany, Japan, Mexico, the U.S. and the U.K. to decompose the patterns of trade growth across various goods classifications during episodes of rapid growth in bilateral trade. I find that bilateral trade growth during these episodes is granular- less than 5\% of goods classifications account for over 65\% of overall bilateral trade growth. I quantitatively assess whether ``Melitz-style trade models, with heterogeneous productivity firms, CES demand and fixed and variable costs of exporting, can match the observed granularity of bilateral trade growth. I find the standard model generates only 10\% of the observed granularity in the data, as measured by the share of total trade growth accounted for by various quantiles of goods classifications. However, by incorporating heterogeneous productivity changes and tariff reductions imputed from the U.S. production and export data, I find that the model generates roughly 70\% as much granularity of trade growth across goods as in the data. When firms export their goods to foreign markets, they often choose between multiple distribution technologies in transporting their goods to their final destination. The second essay extends the standard trade model by incorporating a choice among two distribution technologies in the exporting process- one low-fixed, high-variable cost method, and one high-fixed, low-variable cost method- and assessing the implications for trade growth across goods. In this model, I find that heterogeneous productivity or tariff changes may lead firms to ``switch\u27\u27 their optimal distribution method- from not-traded to traded, or from the low-fixed cost to the high-fixed cost technology. This results in disproportionately larger trade growth for these types of firms, since they benefit from a double reduction in the variable costs of exporting- the direct effect of the fall in trade costs, and the indirect effect of switching to a lower variable cost distribution method. Calibrating this model to bilateral trade flows, I find that model simulations with multiple distribution technologies generate up to 90-95\% of the granularity in trade growth observed in the data. The third essay examines the role of variation in transportation options- what I denote the ``supply network\u27\u27- on observed price differences between locations for a specific good, retail gasoline. I use a unique data set of weekly gasoline prices across 44 Canadian cities to analyze how the existence of variation in the available modes of transportation for gasoline between cities (via pipeline, marine tanker, rail or truck) accounts for observed price differences across locations. I find that the supply network is significant- cities connected by lower per-unit cost methods like pipelines or seaports exhibit smaller mean- and weekly-price differences than those connected only by road or rail, after controlling for variables such as distance, regional effects and market size

Inequality and the American classroom:: Experiential strategies for teaching social justice

Purpose: The purpose of this study is to examine the impact of a mixed format, experiential course on changes in Honors students’ attitudes about various issues of inequality.  Methodology: Students enrolled in the course (N = 75), taught during the 2016 Presidential election, were asked about their opinions on a variety of inequality topics using a pre-test and post-test survey, with the post-test survey including questions on how perceptions of inequality had changed over the course of the semester.  Findings and implications: Results indicate that some students became more self-aware of their position in society and were less sure that people in general, and they themselves in particular, would be responsible for their own hard work. Importantly, students were less likely to believe that people faced fair and equal opportunities in the labor market and their overall level of support for unions increased during the semester. Most students agreed that the outside speakers, a key component of the course, provided new information on various aspects of inequality and impacted their overall perceptions of inequality. However, students were much less agreed on how they felt both about the future of the country and the future of inequality

Advancing Alternative Analysis: Integration of Decision Science.

Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and viability of potential substitutes for hazardous chemicals.Assess whether decision science may assist the alternatives analysis decision maker in comparing alternatives across a range of metrics.A workshop was convened that included representatives from government, academia, business, and civil society and included experts in toxicology, decision science, alternatives assessment, engineering, and law and policy. Participants were divided into two groups and prompted with targeted questions. Throughout the workshop, the groups periodically came together in plenary sessions to reflect on other groups' findings.We conclude the further incorporation of decision science into alternatives analysis would advance the ability of companies and regulators to select alternatives to harmful ingredients, and would also advance the science of decision analysis.We advance four recommendations: (1) engaging the systematic development and evaluation of decision approaches and tools; (2) using case studies to advance the integration of decision analysis into alternatives analysis; (3) supporting transdisciplinary research; and (4) supporting education and outreach efforts

WII-FIT FOR BALANCE AND GAIT IN SKILLED NURSING FACILITY: A RETROSPECTIVE STUDY

Background: Falls in elderly are a major public health problem. Poor balance and gait abnormalities are risk factors for falls. Exercise improves gait and balance in elderly. However, it is difficult to engage patients in exercise programs. Wii-Fit might bridge this gap by providing high level of engagement at an affordable price. Wii-Fit is a Nintendo game used for balance, yoga, aerobics, and strength training. It is a TV based self-directed activity. Virtual trainers talk the user through the activity and track progress while visual and auditory feedback improve engagement. Anecdotal reports suggest improvement in balance and social benefits with Wii-Fit, but no systematic studies are available. Objective: To compare the effect of Wii-Fit augmentation to physical therapy alone in subjects undergoing rehabilitation in skilled nursing facility (SNF) using a retrospective chart review. Methods: 100 charts were reviewed of which seventeen patients were noted to have used Wii-Fit during their rehabilitation. These subjects were matched with seventeen controls who did physical therapy alone. Results: There were no baseline differences between the groups. The mean age was 77.7 years, with 11 females in each group. All the subjects were Caucasians. The average length of stay was 30 days in each group. Mean duration of the Wii-Fit use was 4-weeks. Wii-Fit augmentation group improved significantly in Activities of Daily Living (p=0.008), balance (p=0.0001), and assistance with gait (p=0.05) when compared to the control group. Conclusion: Wii-Fit can be used safely in a SNF, and it may improve balance, gait, and functional status

The COVID-19 pandemic and OBGYN residency training: We have a problem and it’s not just masks

Background: The COVID-19 pandemic has left no one untouched. Resident trainees have been driven to reconsider virtually every component of their daily lives. The purpose of this pilot study is to evaluate the impact of the COVID-19 pandemic on Obstetrics and Gynecology (OBGYN) residency training and education. Methods: A cross-sectional pilot study was conducted between 2/2022 and 5/2022. A survey was created and distributed to OBGYN residents. The survey queried the effects of the pandemic on OBGYN residents’ procedure skills training and mental health. Results: A total of 95 OBGYN residents across programs affiliated with each American College of Obstetricians and Gynecologists (ACOG) district participated in the survey. Among them, just over half (n = 52, 55%) self-identified as under-represented minorities. A significant majority, 80% (n = 81), felt their gynecological training was inadequate, with 70% of fourth-year residents expressing a lack of confidence in their ability to independently practice gynecology after graduation. This lack of confidence among fourth-year residents suggests a notable disparity in readiness for independent gynecological practice, linked to meeting ACGME requirements before completing their residency (p = 0.013). Among the residents who reported a negative impact of the pandemic on their mental health (n = 76, 80%), about 40% (n = 31) had contemplated self-harm or knew a colleague who considered or attempted suicide (p < 0.001). This issue was especially pronounced in residents experiencing burnout (n = 44, 46%), as nearly half (n = 19, 43%) reported suicidal thoughts or knew someone in their program who had such thoughts or engaged in self-harm (p = 0.048). Conclusions: Residents expressed concerns about reduced hands-on gynecological training and doubts about their readiness for independent practice post-residency, highlighting the need for enhanced support through mentorship and revised training curriculums. Additionally, despite the availability of mental health resources to address pandemic-induced burnout, their underuse suggests a need for more accessible time for residents to use at their discretion and flexible training schedules that encourage mental health support resource utilization

Doubling Expression of the Low Density Lipoprotein Receptor by Truncation of the 3′-Untranslated Region Sequence Ameliorates Type III Hyperlipoproteinemia in Mice Expressing the Human ApoE2 Isoform

The primary receptor mediating clearance of apolipoprotein (apo)E- and apoB100-containing lipoproteins from the circulation is the low density lipoprotein (LDL) receptor. Reduced expression of the LDLR is believed to be a precipitating factor in the pathogenesis of type III hyperlipoproteinemia (HLP) in some humans homozygous for the apoE2 allele (APOE*2). To test the effect of genetic changes in LDL receptor expression on the pathogenesis of type III HLP, we have generated a variant allele at the endogenous mouse Ldlr locus that expresses the human LDL receptor transcript. Transcription of the human LDLR minigene is regulated by the endogenous mouse promoter sequence, but a truncation of 3'-untranslated region results in increased mRNA stability. Consequently, in liver of heterozygotes, steady state levels of mouse and human LDLR transcripts are 50 and 180% the levels of total transcript in wild type mice, respectively. Overall, the 2.3-fold normal level of LDLR message in heterozygotes completely ameliorates type III HLP caused by the homozygosity for the human APOE*2 allele, normalizing their plasma lipoprotein profile. We conclude that a modest increase in expression of the LDLR through message stabilization is sufficient to prevent precipitation of type III HLP in mice