Nuclear Magnetic Resonance Characterization of Dynamics in Novel Electrochemical Materials

As our daily use of electronics and electronic technology grows, so does the societal need for sustainable, renewable and portable electrical power. To this end, materials of interest in the electrochemical world are needed to advance the frontier of battery science and energy storage technologies so that a safer, more efficient and reliable electrical future can be realized. This work focuses on characterization of materials primarily of interest for use as electrolytes in rechargeable Lithium-Ion Batteries (LIBs). Despite their extraordinary power, LIB application in certain fields, such as in electric vehicles, has been limited due to performance and safety concerns. It is to overcome this barrier that the efforts of characterization studies such as this are needed, so that the next generation of batteries can perform reliably and safely in all applications. In this work the dynamics of a novel solid polymer electrolyte are discussed, and their disruptive implications on the battery industry. A system of Ionic Liquids (IL) which are candidate electrolyte solvents are examined using Fast Field Cycling (FFC) NMR. A deep eutectic solvent system of glycerol-d8 and a polar salt Choline Chloride is probed using High Pressure Nuclear Magnetic Resonance (HP-NMR) studies

Machine learning methods for automatic silent speech recognition using a wearable graphene strain gauge sensor

Silent speech recognition is the ability to recognise intended speech without audio information. Useful applications can be found in situations where sound waves are not produced or cannot be heard. Examples include speakers with physical voice impairments or environments in which audio transference is not reliable or secure. Developing a device which can detect non-auditory signals and map them to intended phonation could be used to develop a device to assist in such situations. In this work, we propose a graphene-based strain gauge sensor which can be worn on the throat and detect small muscle movements and vibrations. Machine learning algorithms then decode the non-audio signals and create a prediction on intended speech. The proposed strain gauge sensor is highly wearable, utilising graphene’s unique and beneficial properties including strength, flexibility and high conductivity. A highly flexible and wearable sensor able to pick up small throat movements is fabricated by screen printing graphene onto lycra fabric. A framework for interpreting this information is proposed which explores the use of several machine learning techniques to predict intended words from the signals. A dataset of 15 unique words and four movements, each with 20 repetitions, was developed and used for the training of the machine learning algorithms. The results demonstrate the ability for such sensors to be able to predict spoken words. We produced a word accuracy rate of 55% on the word dataset and 85% on the movements dataset. This work demonstrates a proof-of-concept for the viability of combining a highly wearable graphene strain gauge and machine leaning methods to automate silent speech recognition.EP/S023046/

Case Study: University at Albany Develops a Guide to Examine Commuting Behavior and Patterns

The University at Albany conducted an examination of campus commuting patterns and behaviors over an eighteen month period. The components included a review of existing options, the development of GIS maps indicating origin points of commutes, a survey of campus perceptions of barriers to using alternative transportation and on-time tracking of mass transit offerings. The study revealed that the success of alternative transportation is hindered by limitations in bus routes and frequency in scheduling, the need for commuters to make additional trips outside their commute route and a distrust of bus reliability

The microstructure and surface morphology of radiopaque tricalcium silicate cement exposed to different curing conditions

Objective. Tricalcium silicate is the major constituent phase in mineral trioxide aggregate (MTA). It is thus postulated that pure tricalcium silicate can replace the Portland cement component of MTA. The aim of this research was to evaluate the microstructure and surface characteristics of radiopaque tricalcium silicate cement exposed to different curing conditions namely at 100% humidity or immersed in either water or a simulated body fluid at 37 ◦C. Methods. The materials under study included tricalcium silicate and Portland cements with and without the addition of bismuth oxide radiopacifier. Material characterization was performed on hydrated cements using a combination of scanning electron microscopy (SEM) with X-ray energy dispersive (EDX) analyses and X-ray diffraction (XRD) analyses. Surface morphology was further investigated using optical profilometry. Testing was performed on cements cured at 100% humidity or immersed in either water or Hank’s balanced salt solution (HBSS) for 1 and 28 days at 37 ◦C. In addition leachate analysis was performed by X-ray fluorescence of the storage solution. The pH of the storage solution was assessed. Results. All the cements produced calcium silicate hydrate and calcium hydroxide on hydration. Tricalcium silicate showed a higher reaction rate than Portland cement and addition of bismuth oxide seemed to also increase the rate of reaction with more calcium silicate hydrate and calcium hydroxide being produced as demonstrated by SEM and XRD analysis and also by surface deposits viewed by the optical profilometer. Cement immersion in HBSS resulted in the deposition of calcium phosphate during the early stages following immersion and extensive calcification after 28 days. The pH of all storage solutions was alkaline. The immersion in distilled water resulted in a higher pH of the solution than when the cements were immersed in HBSS. Leachate analysis demonstrated high calcium levels in all cements tested with higher levels in tricalcium silicate and bismuth replaced cements. Significance. Tricalcium silicate cement is more bioactive than Portland cement as demonstrated by various characterization techniques. The bioactivity was monitored by measuring the production of calcium hydroxide and the formation of calcium phosphate when in contact with simulated body fluids.peer-reviewe

The implementation and evaluation of a media literacy intervention about PAES use in sport science students

With respect to both competitive and amateur/fitness sports, media may strongly influence young people’s opinions and behaviors concerning the use of PAES (Performance and Appearance Enhancing Substances). The present investigation addressed this topic by focusing on sport sciences students’ beliefs concerning the possible role of media related to the implementation and evaluation of a PAES-focus media literacy intervention conducted with sport science students. This study relied on a sample of 521 students (attrition rate 10.3%) (45.1% female, mean age = 22.6, SD = 2.20), which provided baseline data on students’ levels of media literacy concerning the use of PAES (i.e. “descriptive sample”), and a sample of 248 students, who participated in and provided data on the media literacy intervention. This latter sample included a group of 128 students (44.5% female, mean age = 23.03, SD = 3.76) who actively participated in the intervention (i.e. “intervention group”), and a group of 120 students who did not (i.e. “control group”, 53.3% female, mean age = 22.25, SD = 2.47). All students filled out media literacy questionnaires targeting students’ awareness of media influence, their views about the realism of media content, their sense of confidence in dealing with media messages, and their positive attitudes toward PAES use. Analyses of questionnaire data showed that students are relatively aware of media influence on people’s views and behaviors with respect to PAES use. At the same time, students also believed that young people do not consider media as “realistic sources” of information; nonetheless, they also did not consider themselves entirely capable of dealing effectively with media messages. With respect to the intervention, students overall appreciated and greatly welcomed the educational program on media literacy, and the analyses of intervention data across intervention and control groups showed that key media literacy variables changed over time, attesting to the overall effectiveness of the intervention

CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations

RATIONALE: Rhinoviruses (RVs) are the major triggers of asthma exacerbations. We have shown previously that lower respiratory tract symptoms, airflow obstruction, and neutrophilic airway inflammation were increased in experimental RV-induced asthma exacerbations. OBJECTIVES: We hypothesized that neutrophil-related CXC chemokines and antimicrobial peptides are increased and related to clinical, virologic, and pathologic outcomes in RV-induced exacerbations of asthma. METHODS: Protein levels of antimicrobial peptides (SLPI, HNP 1–3, elafin, and LL-37) and neutrophil chemokines (CXCL1/GRO-α, CXCL2/GRO-β, CXCL5/ENA-78, CXCL6/GCP-2, CXCL7/NAP-2, and CXCL8/IL-8) were determined in bronchoalveolar lavage (BAL) fluid of 10 asthmatics and 15 normal controls taken before, at day four during and 6 weeks post-experimental infection. RESULTS: BAL HNP 1–3 and Elafin were higher, CXCL7/NAP-2 was lower in asthmatics compared with controls at day 4 (P = 0.035, P = 0.048, and P = 0.025, respectively). BAL HNP 1–3 and CXCL8/IL-8 were increased during infection (P = 0.003 and P = 0.011, respectively). There was a trend to increased BAL neutrophils at day 4 compared with baseline (P = 0.076). BAL HNP 1–3 was positively correlated with BAL neutrophil numbers at day 4. There were no correlations between clinical parameters and HNP1–3 or IL-8 levels. CONCLUSIONS: We propose that RV infection in asthma leads to increased release of CXCL8/IL-8, attracting neutrophils into the airways where they release HNP 1–3, which further enhances airway neutrophilia. Strategies to inhibit CXCL8/IL-8 may be useful in treatment of virus-induced asthma exacerbations

HST Observations of Chromospheres in Metal Deficient Field Giants

HST high resolution spectra of metal-deficient field giants more than double the stars in previous studies, span about 3 magnitudes on the red giant branch, and sample an abundance range [Fe/H]= -1 to -3. These stars, in spite of their age and low metallicity, possess chromospheric fluxes of Mg II (2800 Angstrom) that are within a factor of 4 of Population I stars, and give signs of a dependence on the metal abundance at the lowest metallicities. The Mg II k-line widths depend on luminosity and correlate with metallicity. Line profile asymmetries reveal outflows that occur at lower luminosities (M_V = -0.8) than detected in Ca K and H-alpha lines in metal-poor giants, suggesting mass outflow occurs over a larger span of the red giant branch than previously thought, and confirming that the Mg II lines are good wind diagnostics. These results do not support a magnetically dominated chromosphere, but appear more consistent with some sort of hydrodynamic, or acoustic heating of the outer atmospheres.Comment: 36 pages, 12 figures, 7 tables, and accepted for publication in The Astronomical Journa

XO-3b: A Massive Planet in an Eccentric Orbit Transiting an F5V Star

We report the discovery of a massive (Mpsini = 13.02 +/- 0.64 Mjup; total mass 13.25 +/- 0.64 Mjup), large (1.95 +/- 0.16 Rjup) planet in a transiting, eccentric orbit (e = 0.260 +/- 0.017) around a 10th magnitude F5V star in the constellation Camelopardalis. We designate the planet XO-3b, and the star XO-3, also known as GSC 03727-01064. The orbital period of XO-3b is 3.1915426 +/- 0.00014 days. XO-3 lacks a trigonometric distance; we estimate its distance to be 260 +/- 23 pc. The radius of XO-3 is 2.13 +/- 0.21 Rsun, its mass is 1.41 +/- 0.08 Msun, its vsini = 18.54 +/- 0.17 km/s, and its metallicity is [Fe/H] = -0.177 +/- 0.027. This system is unusual for a number of reasons. XO-3b is one of the most massive planets discovered around any star for which the orbital period is less than 10 days. The mass is near the deuterium burning limit of 13 Mjup, which is a proposed boundary between planets and brown dwarfs. Although Burrows et al. (2001) propose that formation in a disk or formation in the interstellar medium in a manner similar to stars is a more logical way to differentiate planets and brown dwarfs, our current observations are not adequate to address this distinction. XO-3b is also unusual in that its eccentricity is large given its relatively short orbital period. Both the planetary radius and the inclination are functions of the spectroscopically determined stellar radius. Analysis of the transit light curve of XO-3b suggests that the spectroscopically derived parameters may be over estimated. Though relatively noisy, the light curves favor a smaller radius in order to better match the steepness of the ingress and egress. The light curve fits imply a planetary radius of 1.25 +/- 0.15 Rjup, which would correspond to a mass of 12.03 +/- 0.46 Mjup.Comment: 26 pages, 10 figures. Accepted by ApJ. Current version has several small corrections as a result of a bug in the fitting softwar

Soluble major histocompatibility complex class I-related chain B molecules are increased and correlate with clinical outcomes during rhinovirus infection in healthy subjects

BACKGROUND: Surface major histocompatibility complex class I-related chain (MIC) A and B molecules are increased by IL-15 and have a role in the activation of natural killer group 2 member D-positive natural killer and CD8 T cells. MICA and MICB also exist in soluble forms (sMICA and sMICB). Rhinoviruses (RVs) are the major cause of asthma exacerbations, and IL-15 levels are decreased in the airways of subjects with asthma. The role of MIC molecules in immune responses in the lung has not been studied. Here, we determine the relationship between MICA and MICB and RV infection in vitro in respiratory epithelial cells and in vivo in healthy subjects and subjects with asthma. METHODS: Surface MICA and MICB, as well as sMICA and sMICB, in respiratory epithelial cells were measured in vitro in response to RV infection and exposure to IL-15. Levels of sMICA and sMICB in serum, sputum, and BAL were measured and correlated with blood and bronchoalveolar immune cells in healthy subjects and subjects with asthma before and during RV infection. RESULTS: RV increased MICA and MICB in vitro in epithelial cells. Exogenous IL-15 upregulated sMICB levels in RV-infected epithelial cells. Levels of sMICB molecules in serum were increased in healthy subjects compared with subjects with stable asthma. Following RV infection, airway levels of sMIC are upregulated, and there are positive correlations between sputum MICB levels and the percentage of bronchoalveolar natural killer cells in healthy subjects but not subjects with asthma. CONCLUSIONS: RV infection induces MIC molecules in respiratory epithelial cells in vitro and in vivo. Induction of MICB molecules is impaired in subjects with asthma, suggesting these molecules may have a role in the antiviral immune response to RV infections

In-the-Gap SU UMa-Type Dwarf Nova, Var73 Dra with a Supercycle of about 60 Days

An intensive photometric-observation campaign of the recently discovered SU UMa-type dwarf nova, Var73 Dra was conducted from 2002 August to 2003 February. We caught three superoutbursts in 2002 October, December and 2003 February. The recurrence cycle of the superoutburst (supercycle) is indicated to be $\sim$60 d, the shortest among the values known so far in SU UMa stars and close to those of ER UMa stars. The superhump periods measured during the first two superoutbursts were 0.104885(93) d, and 0.10623(16) d, respectively. A 0.10424(3)-d periodicity was detected in quiescence. The change rate of the superhump period during the second superoutburst was $1.7\times10^{-3}$, which is an order of magnitude larger than the largest value ever known. Outburst activity has changed from a phase of frequent normal outbursts and infrequent superoutbursts in 2001 to a phase of infrequent normal outbursts and frequent superoutbursts in 2002. Our observations are negative to an idea that this star is an related object to ER UMa stars in terms of the duty cycle of the superoutburst and the recurrence cycle of the normal outburst. However, to trace the superhump evolution throughout a superoutburst, and from quiescence more effectively, may give a fruitful result on this matter.Comment: 9 pages, 8 figures, submitted to A&