Profile of multi drug resistant (MDR) and rifampicin resistant TB patients treated under category IV of RNTCP

Background: The emergence of resistance to drugs used to treat tuberculosis (TB) and particularly multidrug resistance TB (MDR-TB) has become a significant health problem and obstacle to effective TB control in India. Present study was conducted to study clinical and sociodemograohic profile of MDR and rifampicin resistant TB patients registered for treatment under RNTCP in Yavatmal district of Maharashtra state.Methods: All drug resistant (MDR and rifampicin resistant) TB patients residents of Yavatmal district, treated at DOTS plus site with Standardized Treatment Regimen (STR) from 1st quarter 2009 to 3rd quarter 2013 were included. Data was obtained from electronic treatment register maintained at DOTS Plus site.Results: There were total 60 confirmed MDR and rifampicin resistant TB patients from Yavatmal district. Male patients (65.00%) were comparatively more than females (35.00%). Almost half (46.67%) of the patients belonged to the productive age group i.e. 30-45 years followed by another one third (35.00%) in the age group of 15-30 years. 93.33% patients were previously treated under RNTCP (under CAT II), out of them 48.51% were failure, 37.50% relapse and 14.29% defaulter.Conclusions: Among MDR and rifampicin resistant TB patients, maximum patients were males, belonged to the social and productive age group, HIV negative and previously treated due to treatment failure

Study of efficacy and safety of bipolar coagulation in total laparoscopic hysterectomy

Aim: To study the efficacy and safety of bipolar coagulation in total laparoscopic hysterectomy. Methods: A single surgeon, single center, retrospective study of one year was conducted in Akola Endoscopy center from 1 May 2010 to 30th April,2011. 200 patients who underwent total laparoscopic hysterectomy for benign conditions were enrolled. Data about the surgical time, estimated blood loss, related complications and length of hospital stay were evaluated. Results: The patients who underwent TLH with bipolar coagulation in the present study, it was found that the mean operating time was 52.83+-12.28 min, mean blood loss was 40.50+-28.02 ml, post-operatively febrile morbidity was found to be in 1.5% of patients and secondary hemorrhage in 2.5% with average hospital stay around 9-10 hours. No patient required blood transfusion or re-laparotomy. There were no intra-operative or anesthetic complications and no case of hernia or mortality. Conclusion: bipolar coagulation for hemostasis used in laparoscopic hysterectomy is safe and effective