Development of solid-lubricated ball-screws for use in space

Ball-screws lubricated by solid lubricant films containing molybdenum disulphide are developed. The ball-screws (shaft diameter: phi 25 mm, length: 667 mm) were operated under a load of 40 to 120 N at a speed of 1.5 to 200 rpm at 10(exp -5) Pa. First, ball-screws made of stainless steel SUS 440C were studied using test equipment originally designed for this study. To reduce weight, the next step taken was to develop a ball-screw made of 6Al-4V-titanium. Long wear-life of more than 1 x 10(exp 7) revolutions was achieved with solid lubricated ball-screws made of SUS 440C and 6Al-4V-titanium in a hard vacuum. According to the surface profile of the shaft measured after 1 x 10(exp 7) revolutions, more solid lubricant remained on the surface of 6Al-4V-titanium than that of stainless steel. Auger and EPMA analysis confirmed lubrication was maintained by solid lubricant on nuts and screws after the lubricant films on the balls were worn off

The Effect of News Article Quality on Ad Consumption

Practical news feed platforms generate a hybrid list of news articles and advertising items (e.g., products, services, or information) and many platforms optimize the position of news articles and advertisements independently. However, they should be arranged with careful consideration of each other, as we show in this study, since user behaviors toward advertisements are significantly affected by the news articles. This paper investigates the effect of news articles on users' ad consumption and shows the dependency between news and ad effectiveness. We conducted a service log analysis and showed that sessions with high-quality news article exposure had more ad consumption than those with low-quality news article exposure. Based on this result, we hypothesized that exposure to high-quality articles will lead to a high ad consumption rate. Thus, we conducted million-scale A/B testing to investigate the effect of high-quality articles on ad consumption, in which we prioritized high-quality articles in the ranking for the treatment group. The A/B test showed that the treatment group's ad consumption, such as the number of clicks, conversions, and sales, increased significantly while the number of article clicks decreased. We also found that users who prefer a social or economic topic had more ad consumption by stratified analysis. These insights regarding news articles and advertisements will help optimize news and ad effectiveness in rankings considering their mutual influence.Comment: 30th ACM International Conference on Information and Knowledge Management (CIKM2021

Decomposition and Interleaving for Variance Reduction of Post-click Metrics

In this study, we propose an efficient method for comparing the post-click metric (e.g., dwell time and conversion rate) of multiple rankings in online experiments. The proposed method involves (1) the decomposition of the post-click metric measurement of a ranking into a click model estimation and a post-click metric measurement of each item in the ranking, and (2) interleaving of multiple rankings to produce a single ranking that preferentially exposes items possessing a high population variance. The decomposition of the post-click metric measurement enables the free layout of items in a ranking and focuses on the measurement of the post-click metric of each item in the multiple rankings. The interleaving of multiple rankings reduces the sample variance of the items possessing a high population variance by optimizing a ranking to be presented to the users so that those items received more samples of the post-click metric. In addition, we provide a proof that the proposed method leads to the minimization of the evaluation error in the ranking comparison and propose two practical techniques to stabilize the online experiment. We performed a comprehensive simulation experiment and a real service setting experiment. The experimental results revealed that (1) the proposed method outperformed existing methods in terms of efficiency and accuracy, and the performance was especially remarkable when the input rankings shared many items, and (2) the two stabilization techniques successfully improved the evaluation accuracy and efficiency.Comment: The 7th ACM SIGIR International Conference on the Theory of Information Retrieval (ICTIR2021

Estimating Sway Angle of Pendulum System Using Hybrid State Observer Incorporating Continuous and Discrete Sensing Signals

This paper presents the design of a hybrid state observer that estimates the sway angle in trolley systems with a pendulum, such as overhead cranes. In the system, sway angle signals detected by angular sensors are generally used for designing the anti-sway control of the pendulum or observing the pendulum state. By contrast, in this study, a linear state observer without sensors is applied to estimate the sway angle of the pendulum. The use of a standard asymptotic state observer leads to estimation error due to the system's nonlinearities and parametric errors. This paper proposes using a hybrid state observer design that combines discrete event sensing with a linear state observer. In the hybrid state observer, the estimation performance is improved by correcting the state of the system based on the discrete sway angle and angular velocity using discrete sensing. In addition, the parametric error of the pendulum length of the system is identified using the same hybrid setting. The effectiveness of the hybrid state observer and the parametric adaptation of the pendulum length are verified by conducting experiments using a downscaled prototype of a trolley system with a pendulum.publishedVersionPaid open acces

Concentration of 2-phenylphenol by organoclays from aqueous sucrose solution

The adsorption of 2-phenylphenol, which is an antifungal agent, onto organically modified clay from aqueous sucrose solution was investigated. 2-Phenylphenol was effectively adsorbed on neostigmine-modified smectites and octadecyltrimethylammoniurh modified smectites even in the presence of sucrose in the starting aqueous solution. Two smectites (a natural montmorillonite, Kunipia F, and a synthetic saponite, Sumecton SA) were used to find clay minerals with lower layer charge density gave larger adsorption capacity for 2-phenylphenol. The result showed the potential application of the organically modified clays to remove 2-phenylphenol from orange extracts. (C) 2014 Published by Elsevier B.V.ArticleAPPLIED CLAY SCIENCE. 109: 64-67 (2015)journal articl

Linking Creativity to Services Marketing ： A Theoretical Review

本研究では、組織行動論において蓄積されてきた個人レベルのクリエイティビティ研究を踏まえ、クリエイティビティの定義を再考することでサービスマーケティング研究への接続可能性を検討する。本研究の理論的貢献として、クリエイティビティ研究をレビューし、Madjar and Ortiz-Walters（２００８）によるクリエイティビティの定義を再解釈することでクリエイティビティを２つに分けたことの積極的な意義を模索し、サービスマーケティング研究への接続可能性について提起したこと、と主張している。最後に、クリエイティビティを２つに分けたことで見えてくるであろう理論的課題について試論的に提示している。論

Electron- and neutrino-nucleus scattering in the impulse approximation regime

A quantitative understanding of the weak nuclear response is a prerequisite for the analyses of neutrino experiments such as K2K and MiniBOONE, which measure energy and angle of the muons produced in neutrino-nucleus interactions in the energy range $0.5-3$ GeV and reconstruct the incident neutrino energy to determine neutrino oscillations. In this paper we discuss theoretical calculations of electron- and neutrino-nucleus scattering, carried out within the impulse approximation scheme using realistic nuclear spectral functions.Comparison between electron scattering data and the calculated inclusive cross section off oxygen, at beam energies ranging between 700 and 1200 MeV, show that the Fermi gas model, widely used in the analysis of neutrino oscillation experiments,fails to provide a satisfactory description of the measured cross sections,and inclusion of nuclear dynamics is needed.Comment: 12 pages, 15 figure

Critical Point Mutations for Hepatitis C Virus NS3 Proteinase

AbstractThe hepatitis C virus NS3 proteinase plays an essential role in processing of HCV nonstructural precursor polyprotein. To detect its processing activity, we developed a simpletrans-cleavage assay. Two recombinant plasmids expressing the NS3 proteinase region and a chimeric substrate polyprotein containing the NS5A/5B cleavage site between maltose binding protein and protein A were co-introduced intoEscherichia colicells. The proteinase processed the substrate at the single site during their polyprotein expression. Deletion analysis indicated that the functionally minimal domain of the NS3 proteinase was composed of 146 amino acids, 1059 to 1204. We isolated several cDNA clones encoding the functional domain of the NS3 proteinase from the sera of patients chronically infected with HCV and determined their proteinase activity by thistrans-cleavage assay. Both active and inactive clones existed in the same patients. Comparative sequence analyses of these clones suggested that certain point mutations seemed to be related to the loss of proteolytic activity. This was confirmed by back mutation experiments. Among the critical mutations, Pro-1168 to Thr and Arg-1135 to Gly were intriguing. These amino acids, which are situated near the oxyanion hole, seem to be essential for maintaining the conformation of the active center of the NS3 proteinase

Loop-Mediated Isothermal Amplification Methods for Diagnosis of Bacterial Meningitis

The rapid, accurate, and efficient identification of an infectious disease is critical to ensure timely clinical treatment and prevention in public health settings. In 2015, meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis was responsible for 379,200 (range: 322,700–444,700) deaths. Clinical features alone cannot determine whether bacterial meningitis is present; an analysis of cerebrospinal fluid (CSF) is essential. Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification method offering an alternative to polymerase chain reaction (PCR). LAMP-based assays for detection of three leading bacteria in CSF for diagnosis of meningitis have been established. The typing assays using LAMP for detection of meningococcal serogroups A, B, C, W, X, and Y as well as H. influenzae serotypes a, b, c, d, e, and f were launched. In comparative analysis of the meningitis pathogen assays, LAMP assays did not yield false negative results, and the detection rate of LAMP assays was superior compared with PCR or conventional culture methods. LAMP assays provide accurate and rapid test results to detect major bacterial meningitis pathogens. Accumulating evidence suggests that LAMP assays have the potential to provide urgently needed diagnostics for bacterial meningitis in resource-limited settings of both developed and developing countries

Resolvins as Regulators of the Immune System

Inflammation is the first response of the immune system to infection or injury, but excessive or inappropriate inflammatory responses contribute to a range of acute and chronic human diseases. Clinical assessment of dietary supplementation of ω-3 polyunsaturated fatty acids (i.e., eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) indicate that they have beneficial impact on these diseases, although the mechanisms are poorly understood at the molecular level. In this decade, it has been revealed that EPA and DHA are enzymatically converted to bioactive metabolites in the course of acute inflammation and resolution. These metabolites were shown to regulate immune cell functions and to display potent anti-inflammatory actions both in vitro and in vivo. Because of their ability to resolve an acute inflammatory response, they are referred to as proresolving mediators, or resolvins. In this review, we provide an overview of the formation and actions of these lipid mediators