Constraints on mass matrices due to measured property of the mixing matrix

It is shown that two specific properties of the unitary matrix $V$ can be expressed directly in terms of the matrix elements and eigenvalues of the hermitian matrix $M$ which is diagonalized by $V$. These are the asymmetry $\Delta(V)= |V_{12}|^2- |V_{21}|^2$, of $V$ with respect to the main diagonal and the Jarlskog invariant $J(V)= {\rm Im}(V_{11}V_{12}^* V_{21}^* V_{22})$. These expressions for $\Delta(V)$ and $J(V)$ provide constraints on possible mass matrices from the available data on $V$.Comment: 5 pages, Late

Open-architecture Implementation of Fragment Molecular Orbital Method for Peta-scale Computing

We present our perspective and goals on highperformance computing for nanoscience in accordance with the global trend toward "peta-scale computing." After reviewing our results obtained through the grid-enabled version of the fragment molecular orbital method (FMO) on the grid testbed by the Japanese Grid Project, National Research Grid Initiative (NAREGI), we show that FMO is one of the best candidates for peta-scale applications by predicting its effective performance in peta-scale computers. Finally, we introduce our new project constructing a peta-scale application in an open-architecture implementation of FMO in order to realize both goals of highperformance in peta-scale computers and extendibility to multiphysics simulations.Comment: 6 pages, 9 figures, proceedings of the 2nd IEEE/ACM international workshop on high performance computing for nano-science and technology (HPCNano06

A Cardiac Rhabdomyoma in a Guinea Pig

A guinea pig (9-week-old) that had been placed in a control group for a pharmacological test was found to have a single nodule on the surface of the right ventricular wall. In a transverse section of the heart after fixation, a whitish mass was found that extended from the subendocardium to the subepicardium of the right ventricular wall. Histopathological examination revealed a spongy network consisting of vacuolated spaces in the myocardium of the right ventricle extending to the myocardium and subepicardium of the right atrium. The vacuolated space was PAS-positive. Immunohistochemical examinations revealed that the lesions contained striated fibers that were positive for anti-desmin and anti-myoglobin. Electron micrographs revealed the lesions resulting in affected striated muscle fibers and accumulations of many glycogen granules. Based on the findings, the lesions were diagnosed as a cardiac rhabdomyoma. This is the first report of application of immunohistochemical examinations to diagnosis of cardiac rhabdomyoma in the guinea pig

La situation juridique au Japon concernant la fin de vie

departmental bulletin pape

Relation between the neutrino and quark mixing angles and grand unification

We argue that there exists simple relation between the quark and lepton mixings which supports the idea of grand unification and probes the underlying robust bi-maximal fermion mixing structure of still unknown flavor physics. In this framework the quark mixing matrix is a parameter matrix describing the deviation of neutrino mixing from exactly bi-maximal, predicting theta_{sol}+theta_C=pi/4, where theta_C is the Cabibbo angle, theta_{atm}+theta_{23}^{CKM}=pi/4 and theta_{13}^{MNS} ~ theta_{13}^{CKM} ~ O(lambda^3), in a perfect agreement with experimental data. Both non-Abelian and Abelian flavor symmetries are needed for such a prediction to be realistic. An example flavor model capable to explain this flavor mixing pattern, and to induce the measured quark and lepton masses, is outlined.Comment: references added, title changed in journa

Effective and Steady Differentiation of a Clonal Derivative of P19CL6 Embryonal Carcinoma Cell Line into Beating Cardiomyocytes

The P19CL6 cell line is a useful model to study cardiac differentiation in vitro. However, large variations were noticed in the differentiation rates among previous reports as well as our individual experiments. To overcome the unstable differentiation, we established P19CL6-A1, a new clonal derivative of P19CL6 that could differentiate into cardiomyocytes more efficiently and stably than the parent using the double stimulation with 5-Aza and DMSO based on the previous report. We also introduced a new software, Visorhythm, that can analyze the temporal variations in the beating rhythms and can chart correlograms displaying the oscillated rhythms. Using P19CL6-A1-derived cardiomyocytes and the software, we demonstrated that the correlograms could clearly display the enhancement of beating rates by cardiotonic reagents. These indicate that a combination of P19CL6-A1 and Visorhythm is a useful tool that can provide invaluable assistance in inotropic drug discovery, drug screening, and toxicity testing

Large Lepton Mixing and Nonsymmetric Mass Matrices with Flavor 2 <-> 3 Symmetry

We analyze the lepton sector of a recently proposed nonsymmetric mass matrix model. Our model gives a unified description of quark and lepton with the same texture form based on an extended flavor $2 \leftrightarrow 3$ symmetry with a phase. By investigating possible types of assignment for masses, we find that the model can lead to large lepton mixings which are consistent with experimental values. We also find that the model predicts a very small value, $1.3\times10^{-10}$, for the lepton mixing matrix element square $|U_{13}|^2$. The CP violating phases in the lepton mixing matrix and a suppression of the averaged neutrino mass in the neutrinoless double beta decay are also predicted.Comment: 15pages, 2figure