福島県内の陸域環境における人為起源I-129の動態

この博士論文は内容の要約のみの公開（または一部非公開）になっています筑波大学 (University of Tsukuba)201

Open-architecture Implementation of Fragment Molecular Orbital Method for Peta-scale Computing

We present our perspective and goals on highperformance computing for nanoscience in accordance with the global trend toward "peta-scale computing." After reviewing our results obtained through the grid-enabled version of the fragment molecular orbital method (FMO) on the grid testbed by the Japanese Grid Project, National Research Grid Initiative (NAREGI), we show that FMO is one of the best candidates for peta-scale applications by predicting its effective performance in peta-scale computers. Finally, we introduce our new project constructing a peta-scale application in an open-architecture implementation of FMO in order to realize both goals of highperformance in peta-scale computers and extendibility to multiphysics simulations.Comment: 6 pages, 9 figures, proceedings of the 2nd IEEE/ACM international workshop on high performance computing for nano-science and technology (HPCNano06

福島県内の陸域環境における人為起源I-129の動態

筑波大学 (University of Tsukuba)201

Multi-physics Extension of OpenFMO Framework

OpenFMO framework, an open-source software (OSS) platform for Fragment Molecular Orbital (FMO) method, is extended to multi-physics simulations (MPS). After reviewing the several FMO implementations on distributed computer environments, the subsequent development planning corresponding to MPS is presented. It is discussed which should be selected as a scientific software, lightweight and reconfigurable form or large and self-contained form.Comment: 4 pages with 11 figure files, to appear in the Proceedings of ICCMSE 200

Changes in Sequential Organ Failure Assessment sub-scores as predictors of mortality in patients with septic acute kidney injury requiring continuous renal replacement therapy

Patients with septic acute kidney injury （AKI） often require continuous renal replacement therapy （CRRT）, but factors that predict their prognosis have been insufficiently established. Thus, this study aimed to evaluate the associations of the Sequential Organ Failure Assessment （SOFA） score, SOFA-sub scores, and SOFA sub-score components with mortality in patients with AKI on CRRT. A total of 231 patients with AKI who required CRRT were enrolled in this retrospective, cohort study. Associations between the SOFA-sub scores on days 1 or 4 of CRRT and all-cause death within 30 days were assessed. The respiratory SOFA sub-score in patients with sepsis on day 1 was associated with mortality. However, this association disappeared on day 4, and coagulation and renal SOFA-sub scores were significantly associated with mortality in patients with sepsis. These findings differed from patients without septic AKI. The baseline respiratory SOFA sub-score was significantly associated with mortality in patients with septic AKI, whereas the coagulation SOFA sub-score became a prognostic factor on day 4. The evaluation of SOFA-sub scores and changes in the factors after CRRT initiation may be useful for predicting prognosis in patients with septic AKI

Hybrid Textures of Neutrinos

We present numerical and comprehensive analyses of the sixty hybrid textures of neutrinos, which have an equality of matrix elements and one zero. These textures are possibly derived from the discrete symmetry. Only six textures among sixty ones are excluded by the present experimental data. Since there are many textures which give similar predictions, the textures are classified based on the numerical results. The neutrinoless double beta decay is also examined in these textures. Our results suggest that there remain still rich structures of the neutrino mass matrix in the phenomenological point of view.Comment: 19 pages, 9 figures; analytical discussions added, table and reference adde

Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report

<p>Abstract</p> <p>Background</p> <p>Gefitinib remains an excellent treatment option for patients with a variety of cancers, including non small cell lung cancer (NSCLC). However, clinicians must be aware of the potential of gefitinib to cause an inflammatory reaction in the skin, lungs and bladder.</p> <p>Case Presentation</p> <p>We present a case on hemorrhagic cystitis and severaly contracted bladder in a patient with NSCLC on gefitinib.</p> <p>Conclusions</p> <p>Further studies are needed to substantiate the association of gefitinib therapy with hemorrhagic cystitis and contracted bladder.</p

V-shaped dislocations in a GaN epitaxial layer on GaN substrate

In this study, V-shaped dislocations in a GaN epitaxial layer on a free-standing GaN substrate were observed. Our investigation further revealed that the V-shaped dislocations were newly generated at the interface in the epilayer rather than propagated from the GaN substrate. V-shaped dislocations consist of two straight parts. The straight parts of the V-shaped dislocations were separated from each other in the m-direction and tilted toward the step-flow direction of the GaN epitaxial layer. The V-shaped dislocations are continuous single dislocations having a Burgers vector component of 1a and an intrinsic stacking fault between their straight parts

Symmetry realization of texture zeros

We show that it is possible to enforce texture zeros in arbitrary entries of the fermion mass matrices by means of Abelian symmetries; in this way, many popular mass-matrix textures find a symmetry justification. We propose two alternative methods which allow to place zeros in any number of elements of the mass matrices that one wants. They are applicable simultaneously in the quark and lepton sectors. They are also applicable in Grand Unified Theories. The number of scalar fields required by our methods may be large; still, in many interesting cases this number can be reduced considerably. The larger the desired number of texture zeros is, the simpler are the models which reproduce the texture.Comment: 13 pages, no figures, plain LaTeX; misprints corrected, a few sentences changed, one reference added, final version for Eur. Phys. J.

Developing Accelerator Mass Spectrometry Capabilities for Anthropogenic Radionuclide Analysis to Extend the Set of Oceanographic Tracers

Recent major advances in Accelerator Mass Spectrometry (AMS) at the Vienna Environmental Research Accelerator (VERA) regarding detection efficiency and isobar suppression have opened possibilities for the analysis of additional long-lived radionuclides at ultra-low environmental concentrations. These radionuclides, including $^{233}$U, $^{135}$Cs, $^{99}$Tc, and $^{90}$Sr, will become important for oceanographic tracer application due to their generally conservative behavior in ocean water. In particular, the isotope ratios $^{233}$U/$^{236}$U and $^{137}$Cs/$^{135}$Cs have proven to be powerful fingerprints for emission source identification as they are not affected by elemental fractionation. Improved detection efficiencies allowed us to analyze all major long-lived actinides, i.e., $^{236}$U, $^{237}$Np, $^{239,240}$Pu, $^{241}$Am as well as the very rare $^{233}$U, in the same 10 L water samples of a depth profile from the northwest Pacific Ocean. For this purpose, a simplified and very flexible chemical purification procedure based on extraction chromatography (a single UTEVA® column) was implemented which can be extended by a DGA® column for Am purification. The procedure was validated with the reference materials IAEA-381/385. With the additional increase in ionization efficiency expected for the extraction of actinides as fluoride molecules from the AMS ion source, a further reduction of chemical processing may become possible. This method was successfully applied to an exemplary set of air filter samples. In order to determine the quantitative $^{237}$Np concentration reliably, a $^{236}$Np spike material is being developed in collaboration with the University of Tsukuba, Japan. Ion-Laser Interaction Mass Spectrometry (ILIAMS), a novel technique for the efficient suppression of stable isobaric background, has been developed at VERA and provides unprecedented detection sensitivity for the fission fragments $^{135}$Cs, $^{99}$Tc, and $^{90}$Sr. The corresponding setup is fully operational now and the isobar suppression factors of >10$^{5}$ achieved, in principle, allow for the detection of the mentioned radionuclides in the environment. Especially for $^{90}$Sr analysis, this new approach has already been validated for selected reference materials (e.g., IAEA-A-12) and is ready for application in oceanographic studies. We estimate that a sample volume of only (1-3) L ocean water is sufficient for $^{90}$Sr as well as for $^{135}$Cs analysis, respectively