153 research outputs found
Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance
This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile)
ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·Π΅ΠΉ ΠΈ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ Π²ΠΊΠ»ΡΡΠ΅Π½Π½ΠΎΡΡΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ Π² ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ-ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΡΡ ΡΡΠ΅Π΄Ρ ΡΠ΅Π³ΠΈΠΎΠ½Π°
The results of studying the influence of environmental factors on the activities of libraries based on the investigation of macroeconomic indicators of socio-economic environment in the Siberian and Far Eastern federal districts.ΠΠ·Π»ΠΎΠΆΠ΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²Π»ΠΈΡΠ½ΠΈΡ ΡΠ°ΠΊΡΠΎΡΠΎΠ² Π²Π½Π΅ΡΠ½Π΅ΠΉ ΡΡΠ΅Π΄Ρ Π½Π° Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΡ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ Π½Π° ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ ΠΌΠ°ΠΊΡΠΎΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ-ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΠ΅Π΄Ρ ΡΠ΅Π³ΠΈΠΎΠ½ΠΎΠ² Π‘ΠΈΠ±ΠΈΡΡΠΊΠΎΠ³ΠΎ ΠΈ ΠΠ°Π»ΡΠ½Π΅Π²ΠΎΡΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠ΅Π΄Π΅ΡΠ°Π»ΡΠ½ΡΡ
ΠΎΠΊΡΡΠ³ΠΎΠ²
ΠΠ°ΡΡΠ½ΡΠ΅ ΡΠΊΠΎΠ»Ρ Π² ΠΎΠ±Π»Π°ΡΡΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ, Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΈ ΠΊΠ½ΠΈΠ³ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ: ΠΊ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π²ΠΎΠΏΡΠΎΡΠ°
The article is devoted to the history of the study, there are determined the criteria and approaches to identification of the scientific schools in the area of library and information science, bibliography science and bibliology. There are presented scientific schools, established by now at the SPSTL SB RAS.Π Π°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΡΡΡ ΠΈΡΡΠΎΡΠΈΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ, ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΠΊΡΠΈΡΠ΅ΡΠΈΠΈ ΠΈ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΠΊ ΠΈΠ΄Π΅Π½ΡΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ Π½Π°ΡΡΠ½ΡΡ
ΡΠΊΠΎΠ» Π² ΠΎΠ±Π»Π°ΡΡΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ, Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΈ ΠΊΠ½ΠΈΠ³ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ Π½Π°ΡΡΠ½ΡΠ΅ ΡΠΊΠΎΠ»Ρ, ΡΠ»ΠΎΠΆΠΈΠ²ΡΠΈΠ΅ΡΡ ΠΊ Π½Π°ΡΡΠΎΡΡΠ΅ΠΌΡ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ Π² ΠΠΠΠ’Π Π‘Π Π ΠΠ
The technology of programmed learning for additional professional education
The article deals with the technology of programmed learning for additional professional education. Marked peculiarities of the technology of programmed learningΠ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Π° ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ Π΄Π»Ρ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ. ΠΠ±ΠΎΠ·Π½Π°ΡΠ΅Π½Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΡΡΠ΅Π½ΠΈ
Competence-based approach to training and retraining
The article deals with the problems of training and retraining of personnel in programs of additional education based on the competence approach. The features of the competence approach are indicated. Special attention is paid to the implementation of the competence approach. The unsolved problems of the competence approach are consideredΠ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Π° ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠΈ ΠΈ ΠΏΠ΅ΡΠ΅ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠΈ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π° ΠΏΠΎ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠ°ΠΌ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΡΠΌ Π½Π° ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠ½ΠΎΡΡΠ½ΠΎΠΌ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π΅. ΠΠ±ΠΎΠ·Π½Π°ΡΠ΅Π½Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠ½ΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π°. ΠΡΠΎΠ±ΠΎΠ΅ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡΠ΄Π΅Π»Π΅Π½ΠΎ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΡΠΌ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠ½ΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π°. Π Π°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ Π½Π΅ ΡΠ΅ΡΠ΅Π½Π½ΡΠ΅ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠ½ΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄
FEATURES OF PROJECT FINANCING OF REAL ESTATE IN THE DIGITAL ECONOMY AND ITS STATE REGULATION
The problematic issues related to investment processes in the real estate market, based on modern tools of project financing, have been considered. The Russian experience of taxation of investment entities in the Russian Federation, the experience of private-public partnership in the process of investing in real estate objects, have been studied, the problems of using project financing by real estate market entities in the conditions of digitalization have been identified. The directions of improvement of financial, economic, social and legal aspects of state regulation of project financing have been proposed in order to ensure a balance of interests of various economic entities, which as States, firms and households are considered. Modern models of real estate financing by the banking sector have been reviewed
INTERDISCIPLINARY APPROACH TO THE LABELLING OF ORGANIC PRODUCTION FOOD
LabellingΒ β the final stage of production, which determines its characteristics and properties. In addition to the main regulated elements of labeling, information about the product distinctive features can be applied to the label, which can influence the potential consumer choice. Complete and reliable information allows not only to identify the product, but also to prevent possible consumer deception. Information falsification is one of the most common ways of misleading consumers.There are several types of marking: consumer, warning, conformity, environmental and special protective. In order to protect the consumer from information falsification for food products, clear rules for marking for mandatory application have been developed, established in the technical regulations of the Customs Union 022/2011 Β«Food products in terms of its markingΒ» and technical regulations for certain types of products (industry products features). In recent years, the organic products production is actively developing, the requirements for which in the countries of the Eurasian Economic Union (EEU) are at the design stage. Organic production is based on the principles of environmental friendliness and humanity, as well as the prohibition of the use of means of production intensification (chemical fertilizers, chemotherapy drugs, artificial food additives, etc.). To control the implementation of these requirements, it is necessary to conduct a full analysis of the production of the product Β«from the field to the counterΒ», which can be carried out only by highly qualified experts. Confirmation of compliance with the requirements is a organic products sign. In world practice, there are several types of eco-labels. The essence of the developed interdisciplinary approach is a comprehensive application of mandatory and voluntary requirements for the organic food products labeling.LabellingΒ β the final stage of production, which determines its characteristics and properties. In addition to the main regulated elements of labeling, information about the product distinctive features can be applied to the label, which can influence the potential consumer choice. Complete and reliable information allows not only to identify the product, but also to prevent possible consumer deception. Information falsification is one of the most common ways of misleading consumers.There are several types of marking: consumer, warning, conformity, environmental and special protective. In order to protect the consumer from information falsification for food products, clear rules for marking for mandatory application have been developed, established in the technical regulations of the Customs Union 022/2011 Β«Food products in terms of its markingΒ» and technical regulations for certain types of products (industry products features). In recent years, the organic products production is actively developing, the requirements for which in the countries of the Eurasian Economic Union (EEU) are at the design stage. Organic production is based on the principles of environmental friendliness and humanity, as well as the prohibition of the use of means of production intensification (chemical fertilizers, chemotherapy drugs, artificial food additives, etc.). To control the implementation of these requirements, it is necessary to conduct a full analysis of the production of the product Β«from the field to the counterΒ», which can be carried out only by highly qualified experts. Confirmation of compliance with the requirements is a organic products sign. In world practice, there are several types of eco-labels. The essence of the developed interdisciplinary approach is a comprehensive application of mandatory and voluntary requirements for the organic food products labeling
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