153 research outputs found

    Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance

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    This article contains data on the frequencies of alleles, genotypes and haplotypes of the single nucleotide polymorphisms (SNPs) rs2279590 and rs1532278 in the CLU gene in a cohort of normal elderly from the Russian population. The SNPs have been reported to be associated with Alzheimer's disease and cognitive functions in genome-wide and candidate genes association studies. Cognitive performance in sample set was estimated by the Montreal Cognitive Assessment (MoCA). The frequencies of alleles, genotypes and haplotypes of two SNPs were calculated in 3 groups: total sample set, sample set with MoCA score less than 21 (the first quartile) and group with MoCA score more than 24 (the fourth quartile)

    ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ статистичСских взаимосвязСй ΠΈ стСпСни Π²ΠΊΠ»ΡŽΡ‡Π΅Π½Π½ΠΎΡΡ‚ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ Π² ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎ-ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡ‡Π΅ΡΠΊΡƒΡŽ срСду Ρ€Π΅Π³ΠΈΠΎΠ½Π°

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    The results of studying the influence of environmental factors on the activities of libraries based on the investigation of macroeconomic indicators of socio-economic environment in the Siberian and Far Eastern federal districts.Π˜Π·Π»ΠΎΠΆΠ΅Π½Ρ‹ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ исслСдования влияния Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² внСшнСй срСды Π½Π° Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π±ΠΈΠ±Π»ΠΈΠΎΡ‚Π΅ΠΊ Π½Π° основании изучСния ΠΌΠ°ΠΊΡ€ΠΎΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎ-экономичСской срСды Ρ€Π΅Π³ΠΈΠΎΠ½ΠΎΠ² Бибирского ΠΈ Π”Π°Π»ΡŒΠ½Π΅Π²ΠΎΡΡ‚ΠΎΡ‡Π½ΠΎΠ³ΠΎ Ρ„Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½Ρ‹Ρ… ΠΎΠΊΡ€ΡƒΠ³ΠΎΠ²

    НаучныС ΡˆΠΊΠΎΠ»Ρ‹ Π² области библиотСковСдСния, библиографовСдСния ΠΈ книговСдСния: ΠΊ ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΡŽ вопроса

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    The article is devoted to the history of the study, there are determined the criteria and approaches to identification of the scientific schools in the area of library and information science, bibliography science and bibliology. There are presented scientific schools, established by now at the SPSTL SB RAS.РассматриваСтся история изучСния, ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ ΠΊΡ€ΠΈΡ‚Π΅Ρ€ΠΈΠΈ ΠΈ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ ΠΈΠ΄Π΅Π½Ρ‚ΠΈΡ„ΠΈΠΊΠ°Ρ†ΠΈΠΈ Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… школ Π² области библиотСковСдСния, библиографовСдСния ΠΈ книговСдСния. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ Π½Π°ΡƒΡ‡Π½Ρ‹Π΅ ΡˆΠΊΠΎΠ»Ρ‹, слоТившиСся ΠΊ настоящСму Π²Ρ€Π΅ΠΌΠ΅Π½ΠΈ Π² Π“ΠŸΠΠ’Π‘ БО РАН

    The technology of programmed learning for additional professional education

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    The article deals with the technology of programmed learning for additional professional education. Marked peculiarities of the technology of programmed learningΠ’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ рассмотрСна тСхнология ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ обучСния для Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ образования. ΠžΠ±ΠΎΠ·Π½Π°Ρ‡Π΅Π½Ρ‹ особСнности Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΡƒΡ‡Π΅Π½ΠΈ

    Competence-based approach to training and retraining

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    The article deals with the problems of training and retraining of personnel in programs of additional education based on the competence approach. The features of the competence approach are indicated. Special attention is paid to the implementation of the competence approach. The unsolved problems of the competence approach are consideredΠ’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ рассмотрСна ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ° ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ ΠΈ ΠΏΠ΅Ρ€Π΅ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ пСрсонала ΠΏΠΎ ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΠ°ΠΌ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ образования, основанным Π½Π° компСтСнтностном ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π΅. ΠžΠ±ΠΎΠ·Π½Π°Ρ‡Π΅Π½Ρ‹ особСнности компСтСнтностного ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π°. ОсобоС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡƒΠ΄Π΅Π»Π΅Π½ΠΎ рСализациям компСтСнтностного ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Π°. Π Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°ΡŽΡ‚ΡΡ Π½Π΅ Ρ€Π΅ΡˆΠ΅Π½Π½Ρ‹Π΅ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ компСтСнтностного ΠΏΠΎΠ΄Ρ…ΠΎΠ΄

    FEATURES OF PROJECT FINANCING OF REAL ESTATE IN THE DIGITAL ECONOMY AND ITS STATE REGULATION

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    The problematic issues related to investment processes in the real estate market, based on modern tools of project financing, have been considered. The Russian experience of taxation of investment entities in the Russian Federation, the experience of private-public partnership in the process of investing in real estate objects, have been studied, the problems of using project financing by real estate market entities in the conditions of digitalization have been identified. The directions of improvement of financial, economic, social and legal aspects of state regulation of project financing have been proposed in order to ensure a balance of interests of various economic entities, which as States, firms and households are considered. Modern models of real estate financing by the banking sector have been reviewed

    INTERDISCIPLINARY APPROACH TO THE LABELLING OF ORGANIC PRODUCTION FOOD

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    LabellingΒ β€” the final stage of production, which determines its characteristics and properties. In addition to the main regulated elements of labeling, information about the product distinctive features can be applied to the label, which can influence the potential consumer choice. Complete and reliable information allows not only to identify the product, but also to prevent possible consumer deception. Information falsification is one of the most common ways of misleading consumers.There are several types of marking: consumer, warning, conformity, environmental and special protective. In order to protect the consumer from information falsification for food products, clear rules for marking for mandatory application have been developed, established in the technical regulations of the Customs Union 022/2011 Β«Food products in terms of its markingΒ» and technical regulations for certain types of products (industry products features). In recent years, the organic products production is actively developing, the requirements for which in the countries of the Eurasian Economic Union (EEU) are at the design stage. Organic production is based on the principles of environmental friendliness and humanity, as well as the prohibition of the use of means of production intensification (chemical fertilizers, chemotherapy drugs, artificial food additives, etc.). To control the implementation of these requirements, it is necessary to conduct a full analysis of the production of the product Β«from the field to the counterΒ», which can be carried out only by highly qualified experts. Confirmation of compliance with the requirements is a organic products sign. In world practice, there are several types of eco-labels. The essence of the developed interdisciplinary approach is a comprehensive application of mandatory and voluntary requirements for the organic food products labeling.LabellingΒ β€” the final stage of production, which determines its characteristics and properties. In addition to the main regulated elements of labeling, information about the product distinctive features can be applied to the label, which can influence the potential consumer choice. Complete and reliable information allows not only to identify the product, but also to prevent possible consumer deception. Information falsification is one of the most common ways of misleading consumers.There are several types of marking: consumer, warning, conformity, environmental and special protective. In order to protect the consumer from information falsification for food products, clear rules for marking for mandatory application have been developed, established in the technical regulations of the Customs Union 022/2011 Β«Food products in terms of its markingΒ» and technical regulations for certain types of products (industry products features). In recent years, the organic products production is actively developing, the requirements for which in the countries of the Eurasian Economic Union (EEU) are at the design stage. Organic production is based on the principles of environmental friendliness and humanity, as well as the prohibition of the use of means of production intensification (chemical fertilizers, chemotherapy drugs, artificial food additives, etc.). To control the implementation of these requirements, it is necessary to conduct a full analysis of the production of the product Β«from the field to the counterΒ», which can be carried out only by highly qualified experts. Confirmation of compliance with the requirements is a organic products sign. In world practice, there are several types of eco-labels. The essence of the developed interdisciplinary approach is a comprehensive application of mandatory and voluntary requirements for the organic food products labeling
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