Dopamine receptors gene expression in male rat hippocampus after administration of MDMA (Ecstasy) [La Expresión Génica de Receptores de Dopamina en el Hipocampo de Ratas Macho Después de la Administración de MDMA (Éxtasis)]

Ecstasy is one of the most popular amusing drugs among young people. Documents indicate some effects of Ecstasy on hippocampus and close relations between dopaminergic functions with reward learning. Therefore, the aim of this study was evaluation of the chronic effects of Ecstasy on memory in male Wistar rats and determination of dopamine receptors' gene expression in hippocampus. Forty adult male Wistar rats randomly distributed in five groups: Control, sham (received 1 ml/kg 0.9 saline) and three experimental groups were: Exp. 1 (2.5 mg/kg), Exp. 2 (5 mg/kg), and Exp. 3 (10 mg/kg) received MDMA intraperitoneally once every 7 days (3 times a day, 3 hours apart) for 4 weeks. Before the first injection animals trained in Shuttle Box memory and tested after the last injection. 24 hours after the final testing, brains of rats were dissected and hippocampus was removed and homogenized. After total RNA extraction and cDNA synthesis, expression of dopamine receptor genes in the hippocampus determined with Real-Time PCR. Our results showed that 2.5 and 5 mg/kg MDMA-treated groups had memory impairment. Also we found that MDMA increased the mRNA expression of dopamine receptors in hippocampus and the highest increase found in dopamine D1 receptors in the 5 mg/kg experimental group. We concluded that low doses of Ecstasy could increase Dopamine takers gene expression in hippocampus and disorder avoidance memory. But in high doses the increase in Dopamine takers gene expression was not as much as that in low doses and avoidance memory disorder was not observed. © 2015, Universidad de la Frontera. All rights reserved

Towards Spinfoam Cosmology

We compute the transition amplitude between coherent quantum-states of geometry peaked on homogeneous isotropic metrics. We use the holomorphic representations of loop quantum gravity and the Kaminski-Kisielowski-Lewandowski generalization of the new vertex, and work at first order in the vertex expansion, second order in the graph (multipole) expansion, and first order in 1/volume. We show that the resulting amplitude is in the kernel of a differential operator whose classical limit is the canonical hamiltonian of a Friedmann-Robertson-Walker cosmology. This result is an indication that the dynamics of loop quantum gravity defined by the new vertex yields the Friedmann equation in the appropriate limit.Comment: 8 page

Bicrossproduct structure of the null-plane quantum Poincare algebra

A nonlinear change of basis allows to show that the non-standard quantum deformation of the (3+1) Poincare algebra has a bicrossproduct structure. Quantum universal R-matrix, Pauli-Lubanski and mass operators are presented in the new basis.Comment: 7 pages, LaTe

Braided Matrix Structure of the Sklyanin Algebra and of the Quantum Lorentz Group

Braided groups and braided matrices are novel algebraic structures living in braided or quasitensor categories. As such they are a generalization of super-groups and super-matrices to the case of braid statistics. Here we construct braided group versions of the standard quantum groups $U_q(g)$. They have the same FRT generators $l^\pm$ but a matrix braided-coproduct \und\Delta L=L\und\tens L where $L=l^+Sl^-$, and are self-dual. As an application, the degenerate Sklyanin algebra is shown to be isomorphic to the braided matrices $BM_q(2)$; it is a braided-commutative bialgebra in a braided category. As a second application, we show that the quantum double D(\usl) (also known as the `quantum Lorentz group') is the semidirect product as an algebra of two copies of \usl, and also a semidirect product as a coalgebra if we use braid statistics. We find various results of this type for the doubles of general quantum groups and their semi-classical limits as doubles of the Lie algebras of Poisson Lie groups.Comment: 45 pages. Revised (= much expanded introduction

Single-, Dual- and Triple-band Frequency Reconfigurable Antenna

The paper presents a frequency reconfigurable slot dipole antenna. The antenna is capable of being switched between single-band, dual-band or triple-band operation. The antenna incorporates three pairs of pin-diodes which are located within the dipole arms. The antenna was designed to operate at 2.4 GHz, 3.5 GHz and 5.2 GHz using the aid of CST Microwave Studio. The average measured gains are 1.54, 2.92 and 1.89 dBi for low, mid and high band respectively. A prototype was then constructed in order to verify the performance of the device. A good level of agreement was observed between simulation and measurement

Spectral noncommutative geometry and quantization: a simple example

We explore the relation between noncommutative geometry, in the spectral triple formulation, and quantum mechanics. To this aim, we consider a dynamical theory of a noncommutative geometry defined by a spectral triple, and study its quantization. In particular, we consider a simple model based on a finite dimensional spectral triple (A, H, D), which mimics certain aspects of the spectral formulation of general relativity. We find the physical phase space, which is the space of the onshell Dirac operators compatible with A and H. We define a natural symplectic structure over this phase space and construct the corresponding quantum theory using a covariant canonical quantization approach. We show that the Connes distance between certain two states over the algebra A (two ``spacetime points''), which is an arbitrary positive number in the classical noncommutative geometry, turns out to be discrete in the quantum theory, and we compute its spectrum. The quantum states of the noncommutative geometry form a Hilbert space K. D is promoted to an operator *D on the direct product *H of H and K. The triple (A, *H, *D) can be viewed as the quantization of the family of the triples (A, H, D).Comment: 7 pages, no figure

Generalized exclusion and Hopf algebras

We propose a generalized oscillator algebra at the roots of unity with generalized exclusion and we investigate the braided Hopf structure. We find that there are two solutions: these are the generalized exclusions of the bosonic and fermionic types. We also discuss the covariance properties of these oscillatorsComment: 10 pages, to appear in J. Phys.

Entanglement and Tensor Product Decomposition for Two Fermions

The problem of the choice of tensor product decomposition in a system of two fermions with the help of Bogoliubov transformations of creation and annihilation operators is discussed. The set of physical states of the composite system is restricted by the superselection rule forbidding the superposition of fermions and bosons. It is shown that the Wootters concurrence is not proper entanglement measure in this case. The explicit formula for the entanglement of formation is found and its dependence on tensor product decompositions of the Hilbert space is discussed. It is shown that the set of separable states is narrower than in two-qubit case. Moreover, there exist states which are separable with respect to all tensor product decompositions of the Hilbert space.Comment: 8pp, published versio

Deformed Minkowski spaces: clasification and properties

Using general but simple covariance arguments, we classify the `quantum' Minkowski spaces for dimensionless deformation parameters. This requires a previous analysis of the associated Lorentz groups, which reproduces a previous classification by Woronowicz and Zakrzewski. As a consequence of the unified analysis presented, we give the commutation properties, the deformed (and central) length element and the metric tensor for the different spacetime algebras.Comment: Some comments/misprints have been added/corrected, to appear in Journal of Physics A (1996