6 research outputs found
Cyclosporiasis Outbreak, Indonesia
We describe an outbreak of Cyclospora cayetanensis infection among Dutch participants at a scientific meeting in September 2001 in Bogor, Indonesia. Fifty percent of the investigated participants were positive for C. cayetanensis. To our knowledge, this outbreak is the first caused by C. cayetanensis among susceptible persons in a disease-endemic area
Successful treatment with chemotherapy and subsequent allogeneic bone marrow transplantation for myeloid blastic crisis of chronic myelogenous leukemia following advanced Hodgkin's disease
Antibodies to Cell Wall Peptidoglycan of Staphylococcus aureus in Patients with Serious Staphilococcal Infections
An enzyme-linked immunoassay was used to detect antibodies to the cell wall
peptidoglycan of Staphylococcus aureus in human sera. All 170 sera from donors
and patients with staphylococcal and nonstaphilococcal infections contained IgG
antibodies to peptidoglycan; antobody levels varied with age, and
transplacental transfer occurred. IgM antibodies to peptidoglycan were not
found in donors and were present in only one patient with serious
staphylococcal infection. Significantly elevated levels of IgG antibodies to
peptidoglycan were observed in 20 (80%) of 25 patients with deep tissue
infection with S. aureus but in only two (9%) of 22 patients with superficial
staphylococcal infection. An increase in levels of antibodies to peptidoglycan
generally coincided with an increase in level of IgG antibodies to teichoic
acid. No cross-reactivity between peptidoglycan and teichoic acid was
observed. Thus, staphylococcal peptidoglycan is immunogenic in humans, and
testing for IgG antibodies to peptidoglycan may be useful in the diagnosis and
follow-up of serious staphylococcal infections