The cumulative overlap distribution function in realistic spin glasses

We use a sample-dependent analysis, based on medians and quantiles, to analyze the behavior of the overlap probability distribution of the Sherrington-Kirkpatrick and 3D Edwards-Anderson models of Ising spin glasses. We find that this approach is an effective tool to distinguish between RSB-like and droplet-like behavior of the spin-glass phase. Our results are in agreement with a RSB-like behavior for the 3D Edwards-Anderson model.Comment: Version accepted in PRB. 12 pages, 10 figure

A bizarre complication of shoulder arthroscopy

A case is presented of an unusual complication of shoulder arthroscopy, which was caused by incorrect location of the posterior portal, inducing neurapraxia of both the axillary and radial nerves, with significant clinical and functional sequelae. A subsequent open surgical neurolysis was required to restore normal nerve function. This type of lesion has not been reported previously

How Implicit Attitudes toward Vaccination Affect Vaccine Hesitancy and Behaviour: Developing and Validating the V-IRAP

Vaccination is one of the most important ways of fighting infectious diseases, such as COVID-19. However, vaccine hesitancy and refusal can reduce adherence to vaccination campaigns, and therefore undermine their effectiveness. Although the scientific community has made great efforts to understand the psychological causes of vaccine hesitancy, studies on vaccine intention have usually relied on traditional detection techniques, such as questionnaires. Probing these constructs explicitly could be problematic due to defense mechanisms or social desirability. Thus, a measure capable of detecting implicit attitudes towards vaccination is needed. To achieve this aim, we designed and validated a new test called the Vaccine-IRAP, or V-IRAP, which is a modified version of the original Implicit Relational Assessment Procedure, or IRAP, task. The V-IRAP allows the unspoken reasons behind vaccine hesitancy to be investigated, and is able to distinguish between positive and negative beliefs on vaccination. The test was assessed in a sample of 151 participants. The V-IRAP showed good internal reliability and convergent validity, with meaningful correlational patterns with explicit measures. Moreover, it revealed incremental validity over such explicit measures. Lastly, the V-IRAP was able to shed light on the implicit attitudes involved in vaccine refusal, revealing negative attitudes relative to vaccine-related risks in non-vaccinated participants. Overall, these results support V-IRAP as a sensitive and reliable tool that could be used in future studies on implicit attitudes toward vaccination

Comment on "Evidence of Non-Mean-Field-Like Low-Temperature Behavior in the Edwards-Anderson Spin-Glass Model"

A recent interesting paper [Yucesoy et al. Phys. Rev. Lett. 109, 177204 (2012), arXiv:1206:0783] compares the low-temperature phase of the 3D Edwards-Anderson (EA) model to its mean-field counterpart, the Sherrington-Kirkpatrick (SK) model. The authors study the overlap distributions P_J(q) and conclude that the two models behave differently. Here we notice that a similar analysis using state-of-the-art, larger data sets for the EA model (generated with the Janus computer) leads to a very clear interpretation of the results of Yucesoy et al., showing that the EA model behaves as predicted by the replica symmetry breaking (RSB) theory.Comment: Version accepted for publication in PRL. 1 page, 1 figur

Weak first order transition in the three-dimensional site-diluted Ising antiferromagnet in a magnetic field

We perform intensive numerical simulations of the three-dimensional site-diluted Ising antiferromagnet in a magnetic field at high values of the external applied field. Even if data for small lattice sizes are compatible with second-order criticality, the critical behavior of the system shows a crossover from second-order to first-order behavior for large system sizes, where signals of latent heat appear. We propose "apparent" critical exponents for the dependence of some observables with the lattice size for a generic (disordered) first-order phase transition.Comment: Final version, accepted for publicatio

A Case of Osteonecrosis of the Jaw in a Patient with Crohn's Disease Treated with Infliximab

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse drug reaction, occurring in patients undergoing treatments with antiresorptive or antiangiogenic agents, such as bisphosphonates, denosumab, or bevacizumab, for different oncologic and non-oncologic diseases. The aim of this study was to report a case of MRONJ in a patient taking infliximab, an anti-TNF-alpha antibody used to treat Crohn's disease, rheumatoid arthritis, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. Case Report: A 49-year-old female patient affected by Crohn's disease, who had been undergoing 250 mg intravenous infliximab every six weeks for 12 years, with no history of antiresorptive or antiangiogenic agent administration, came to our attention for post-surgical MRONJ, associated with a wide cutaneous necrotic area of her anterior mandible. Following antibiotic cycles, the patient underwent surgical treatment with wide bone resection and debridement of necrotic tissues; after prolonged follow-up (16 months), the patient completely healed without signs of recurrence. Conclusions: Prevention of MRONJ by dental check-up before and during treatments with antiresorptive treatments (bisphosphonates or denosumab) is a well-established procedure. Although further studies are required to confirm the role of infliximab in MRONJ, based on the results of this study, we propose that patients who are going to be treated with infliximab should also undergo dental check-up before starting therapy, to possibly avoid MRONJ onset

Light-emitting textiles: Device architectures, working principles, and applications

E-textiles represent an emerging technology aiming toward the development of fabric with augmented functionalities, enabling the integration of displays, sensors, and other electronic components into textiles. Healthcare, protective clothing, fashion, and sports are a few examples application areas of e-textiles. Light-emitting textiles can have different applications: Sensing, fashion, visual communication, light therapy, etc. Light emission can be integrated with textiles in different ways: Fabricating light-emitting fibers and planar light-emitting textiles or employing side-emitting polymer optical fibers (POFs) coupled with light-emitting diodes (LEDs). Different kinds of technology have been investigated: Alternating current electroluminescent devices (ACELs), inorganic and organic LEDs, and light-emitting electrochemical cells (LECs). The different device working principles and architectures are discussed in this review, highlighting the most relevant aspects and the possible approaches for their integration with textiles. Regarding POFs, the methodology to obtain side emissions and the critical aspects for their integration into textiles are discussed in this review. The main applications of light-emitting fabrics are illustrated, demonstrating that LEDs, alone or coupled with POFs, represent the most robust technology. On the other hand, OLEDs (Organic LEDs) are very promising for the future of light-emitting fabrics, but some issues still need to be addressed

Physical assessment of toxicology at nanoscale: nano dose-metrics and toxicity factor

In this work, we propose a systematic and reproducible evaluation of nanoparticles (NPs) toxicology in living systems, based on a physical assessment and quantification of the toxic effects of NPs by the experimental determination of the key parameter affecting the toxicity outcome (i.e., the number of NPs) and of the NPs "toxicity factor". Such a strategy was applied to a well determined scenario, i.e., the ingestion of citrate-capped gold NPs (AuNPs) of different sizes by the model system Drosophila melanogaster. Using these AuNPs as a reference toxicity standard, we were able to define different regions in the multiparametric space of toxicity, enabling the classification of the toxic levels of other nanomaterials, such as quantum dots and pegylated AuNPs. This approach may pave the way to a systematic classification of nanomaterials, leading to important developments in risk assessment and regulatory approval, as well as in a wide range of nanomedicine applications

Flexible distributed Bragg reflectors as optical outcouplers for OLEDs based on a polymeric anode

Top-emitting OLEDs (TOLEDs) represent a promising technology for the development of next-generation flexible and rollable displays, thanks to their improved light outcoupling and their compatibility with opaque substrates. Metal thin films are the most used electrodes for the manufacturing of TOLEDs, but they show poor resistance to mechanical deformation, which compromises the long-term durability of flexible devices. This paper reports the exploitation of a dielectric mirror (DBR) based on seven pairs of TiO2 and SiO2 combined with a polymeric electrode as an alternative to the bottom metal electrode in flexible TOLEDs. The DBR showed a maximum reflectivity of 99.9% at about 550 nm, and a stop-band width of about 200 nm. The reflectivity remained unchanged after bending and treatment with water and solvents. Green TOLED devices were fabricated on top of DBRs, and demonstrated good stability in terms of electro-optical and colorimetric characteristics, according to varying viewing angles. These results demonstrate that the combination of the flexible DBR with the polymeric anode is an interesting strategy for improving the durability of flexible TOLEDs for display applications, implemented on different kinds of free-standing ultra-thin substrates