22 research outputs found
Influência do estrógeno e do interferon γ sobre a expressão da indoleamina-2,3-dioxigenase em cultura de células de placenta e embriões de ratas Wistar
Radiations and male fertility
During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental,
health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat and extreme
exposure to pesticides, radiations, radioactivity and other hazardous substances. We are surrounded by several types
of ionizing and non-ionizing radiations and both have recognized causative effects on spermatogenesis. Since it is
impossible to cover all types of radiation sources and their biological effects under a single title, this review is
focusing on radiation deriving from cell phones, laptops, Wi-Fi and microwave ovens, as these are the most
common sources of non-ionizing radiations, which may contribute to the cause of infertility by exploring the effect
of exposure to radiofrequency radiations on the male fertility pattern. From currently available studies it is clear that
radiofrequency electromagnetic fields (RF-EMF) have deleterious effects on sperm parameters (like sperm count,
morphology, motility), affects the role of kinases in cellular metabolism and the endocrine system, and produces
genotoxicity, genomic instability and oxidative stress. This is followed with protective measures for these radiations
and future recommendations. The study concludes that the RF-EMF may induce oxidative stress with an increased
level of reactive oxygen species, which may lead to infertility. This has been concluded based on available
evidences from in vitro and in vivo studies suggesting that RF-EMF exposure negatively affects sperm quality
Effect of alpha-tocopherol supplementation on renal oxidative stress and Na+/K+-adenosine triphosphatase in ethanol treated Wistar rats
608-610Ethanol intoxication resulted in high extent of lipid peroxidation, and reduction in antioxidant defenses (decreased GSH, GSH/GSSG ratio, and catalase, SOD and GPx activities) and (Na+/K+)-ATPase activity in kidney. Alpha-tocopherol treatment effectively protected kidney from ethanol induced oxidative challenge and improved renal (Na+/K+)-ATPase activity. Ethanol induced oxidative stress in the kidney and decreased (Na+/K+)-ATPase activity could be reversed by treatment with ascorbic acid
Effects of exposure to electromagnetic field radiation (EMFR) generated by activated mobile phones on fasting blood glucose
Objective: Extensive use of mobile phones has been accompanied by a common public debate about possible adverse effects on human health. No study has been published so far to establish any association between the fastest growing innovation of mobile phone and fasting blood glucose. The aim was to determine the effects of exposure to electromagnetic field radiation generated by mobile phones on fasting blood glucose in Wistar Albino rats. Materials and Methods: 40 Male Albino rats (Wistar Strain) were divided into 5 equally numerous groups. Group A served as the control one, group B received mobile phone radiation for less than 15 min/day, group C: 15-30 min/day, group D: 31-45 min/day, and group E: 46-60 min/day for a total period of 3 months. Fasting blood glucose was determined by using Spectrophotometer and serum insulin by Enzyme-linked Immunosorbent Assay (ELISA). The Homeostatic Model (HOMA-B) was applied for the assessment of β-cell function and (HOMA-IR) for resistance to insulin. Results: Wister Albino rats exposed to mobile phone radiation for longer than 15 min a day for a total period of 3 months had significantly higher fasting blood glucose (p < 0.015) and serum insulin (p < 0.01) compared to the control group. HOMA-IR for insulin resistance was significantly increased (p < 0.003) in the groups that were exposed for 15-30 and 46-60 min/day compared to the control rats. Conclusion: The results of the present study show an association between long-term exposure to activated mobile phones and increase in fasting blood glucose and serum insulin in Albino rats