Report on Three Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm

WOS: 000440491800017PubMed ID: 2966603

Psoriasis and 5HT-R2C Gene Polymorphism: Association between Clinical, Demographic and Therapeutic Parameters in the Turkish Population

We aimed to investigate the relationship between single nucleotide polymorphism (SNP) in the promoter region of the 5-HT-R2C gene and stress-related disease psoriasis in the Turkish population. The putative association between the 5-HTR2C variant (rs6318 Cys23Ser allele) and patients with psoriasis was investigated. 100 patients with psoriasis and 100 age-sex matched, unrelated healthy subjects representing the control group were included in the study. The PCR-RFLP method was used for genotyping the 5-HTR2C variation. There was no statistically difference in terms of genotype distributions and allele frequencies between the control subjects and patients with psoriasis (P=0.360 and P=0.439, respectively). The comparison between the presence and absence of the 5-HTR2C gene rs6318 G allele within the determined clinical subsets resulted in a significant difference with regard to treatment methodology only when conventional therapy and one or more medical therapy was compared (P=0.021). This study is the first clinical study to investigate the association between 5-HTR2C polymorphism and psoriasis. The role of the 5-HTR2C gene should be examined with more parameters in a larger case series

The Diagnostic Roles of Cytokines in Hepatobiliary Cancers

Objectives. The aim of this study was to investigate the role of several cytokines including IL-2, IL-6, IL-8, IL-10, and TNF-α in the diagnosis of HPB cancers. Materials and Methods. The prospective study was performed between October 2007 and September 2014. The study included 226 patients who were divided into 5 groups depending on their postoperative and histopathologic diagnosis: Control group included 30 healthy volunteers. Hepatocellular cancer (HCC) group included 24 patients diagnosed with HCC. Gallbladder cancer (GBC) group included 36 patients diagnosed with GBC. Cholangiocellular carcinoma group included 64 patients diagnosed with cholangiocellular carcinoma. Pancreatic cancer group included 72 patients diagnosed with pancreatic cancer. Serum levels of IL-2, IL-6, IL-8, IL-10, and TNF-α were measured using an enzyme-linked immunosorbent assay kit in accordance with the guidelines of the producer. Results. Serum TNF-α concentration was significantly higher in the cholangiocellular carcinoma and pancreatic cancer groups compared to other groups. IL-6 and IL-10 were significantly increased in both the HCC and GBC groups, IL-2, IL-6, IL-10, and TNF-α in the cholangiocellular carcinoma group, and IL-2, IL-6, IL-8, and TNF-α in the pancreatic cancer group. Conclusion. We suggest that cytokines can be used as useful markers in the diagnosis of HPB cancers

Black Sea Hydrate Formation Conditions of Methane Hydrogen Sulfide Mixtures

The objective of the study is to examine hydrate formation conditions of methane-hydrogen sulfide mixtures providing the Black Sea conditions. An experimental work is carried out by using a system that contains a high-pressure hydrate formation cell with different H2S concentrations and both brine and distilled water. Hydrate equilibrium conditions, the number of moles of free gas in the hydrate formation cell, and rate of hydrate formation are determined. Effects of H2S concentration on the hydrate formation conditions are also obtained during the study. It is observed that with an increase in H2S concentration, the methane hydrogen sulfide hydrate formation conditions reach higher equilibrium temperature values at a given pressure. According to the experimental results, it is concluded that the Black Sea has suitable conditions for hydrate formation of methane hydrogen sulfide mixtures

Hydrate Formation Conditions of Methane Hydrogen Sulfide Mixtures

The objective of the study is to determine hydrate formation conditions of methane-hydrogen sulfide mixtures. An experimental work is carried out with different H2S concentrations and both brine and distilled water. The Black Sea conditions, which are suitable for methane-hydrogen sulfide hydrate formation, are examined. Effects of H2S concentration and salinity on the hydrate formation conditions are also obtained during the study. It is concluded that an increase in the salinity shifts the methane-hydrogen sulfide hydrate equilibrium condition to lower equilibrium temperatures at a given pressure. With an increase in H2S concentration, the methane hydrogen sulfide hydrate formation conditions reach higher equilibrium temperature values at a given pressure

Hydrate Inhibition with PEO (Poly 2-ethyl-2-oxazoline)

This study is aimed at investigating the effects of a poly 2-ethyl-2-oxazoline-type polymer on the prevention of methane hydrate formation. During the study, seven experiments with low concentrations of poly 2-ethyl-2-oxazoline (0 to 1 wt%) were run in a batch-type reactor. The analysis of the experimental study indicates that poly 2-ethyl-2-oxazoline can be considered as a potential kinetic inhibitor for hydrate formation

REPORT ON THREE PATIENTS WITH BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM

8th International Eurasian Hematology Oncology Congress (EHOC) -- OCT 18-21, 2017 -- Istanbul, TURKEYWOS: 00041674260013