Seroparasitological evaluation of Plasmodium vivax malaria and stability of the anti-plasmodial antibodies in Parsabad Ardabil province

زمینه و هدف: مالاریا یکی از مهمترین بیماری های انگلی در جهان و برخی از مناطق ایران محسوب می شود. علاوه بر مناطق آندمیک این بیماری در جنوب و جنوب شرقی، در سال های اخیر، شمال غربی کشور نیز با ظهور مالاریای ویواکس مواجه شده است. این مطالعه به منظور بررسی مقایسه ای سروپارازیتولوژی مالاریا با روش ایمونوفلوئورسانس غیر مستقیم (IFA) و پایداری آنتی بادی های ضد پلاسمودیومی شهرستان پارس آباد واقع در استان اردبیل در شمال غربی ایران صورت گرفته است. روش بررسی: این مطالعه توصیفی – تحلیلی بر روی 250 نمونه از افراد مبتلا به مالاریا که با روش میکروسکوپی تایید شده و تحت درمان با ترکیبات ضد مالاریا بوده اند و 250 نمونه از گروه شاهد منفی، بین سال های 84-1382 انجام پذیرفت. پایداری آنتی بادی‌های ضد پلاسمودیوم ویواکس در سرم های تهیه شده از گروه های آزمون و شاهد در پایان دوره مطالعه با استفاده از روش های ایمونوفلوئورسانس (IFA) و مستقیم مورد ارزیابی قرار گرفتند. داده های به دست آمده با استفاده از آزمون آماری آنالیز واریانس یک طرفه و t دانشجویی تجزیه و تحلیل گردید. یافته ها: در بررسی انجام شده به روش میکروسکپی، از مبتلایان به مالاریا همگی به پلاسمودیوم ویواکس آلوده و گروه شاهد همگی منفی بودند و هیچگونه آلودگی مضاعف با این روش مشاهده نشد. نتیجه بررسی سروپارازیتولوژیک با روش ایمونوفلوئورسانس نشانگر آن بود که 47 مورد (19) از گروه آزمون و 4 مورد (6/1) از گروه شاهد آنتی بادی ضد پلاسمودیوم ویواکس را دارا بودند (001/0

The Prevalence of Risk Factors of Non-Communicable Diseases in Fars Province

Background: Although a significant success has been achieved in prevention and control of non-communicable chronic diseases, the incidence and prevalence of these diseases have significantly increased. The aim of the present study was to assess the prevalence of risk factors of non-communicable chronic diseases in Fars Province, in 2008. Methods: Using the database of the Iranian Post Company, selected samples were recruited systematically by using multi-stage cluster sampling method (50 clusters of people, each cluster consisted of 20 persons totally 920 individuals) from the whole province. Selected individuals were approached in designated days and related questionnaires were filled. Data entering were done using the EPI-info version 6 software and were analyzed using the STATA version 10. Results: Obesity was seen in 20.3% and 9.4% of the female and male participants. The mean systolic and diastolic blood pressure was estimated to be 120.8 and 75.3 mmHg. Daily intake of fruit and vegetables was 1.3 and 1.2 servings. And 14.1% of the participants were cigarette smokers. Conclusion: We conclude that risk factors of non-communicable chronic disease are not equally distributed in men and women. Overweight, obesity, abdominal obesity, and inactivity are more prevalent in women, while smoking and high blood pressure are more prevalent in men

Patterns of co-association of C-reactive protein and nitric oxide in malaria in endemic areas of Iran

In addition to numerous immune factors, C-reactive protein (CRP) and nitric oxide (NO) are believed to be molecules of malaria immunopathology. The objective of this study was to detect CRP and NO inductions by agglutination latex test and Griess microassay respectively in both control and malaria groups from endemic areas of Iran, including Southeastern (SE) (Sistan & Balouchestan, Hormozgan, Kerman) and Northwestern (NW) provinces (Ardabil). The results indicated that CRP and NO are produced in all malaria endemic areas of Iran. In addition, more CRP and NO positive cases were observed amongst malaria patients in comparison with those in control group. A variable co-association of CRP/NO production were detected between control and malaria groups, which depended upon the malaria endemic areas and the type of plasmodia infection. The percentage of CRP/NO positive cases was observed to be lower in NW compare to SE region, which may be due to the different type of plasmodium in the NW ( Plasmodium vivax ) with SE area (P. vivax, Plasmodium falciparum , mixed infection). The fluctuations in CRP/NO induction may be consistent with genetic background of patients. Although, CRP/NO may play important role in malaria, their actual function and interaction in clinical forms of disease remains unclear

Childhood cancer epidemiology based on cancer registry’s data of Fars province of Iran

Introduction: Childhood cancers are very rare diseases and accounting for about one percent of all cancers, also it is one of the main causes of death among children. The aim of this paper was to ascertain of childhood cancers epidemiology in Fars province. Materials and Methods: In this epidemiological study that Fars province cancer registry was used, frequency distribution of childhood cancers in less than 19 year old in 2001up to 2008 was evaluated and incidence rates were calculated per 1000,000 people a year. Data were analyzed by running SPSS software, version 16 (SPSS Inc., Chicago, IL) and M.S. Excel version 2007. Results: Out of 1610 registered new cancer cases that were resident of Fars province, blood cell cancers were most common type of cancers. 57 % of cases were male and 15-18 year old age group in comparison to other groups has been the most frequent (30.7%). The mean age of cases at diagnose time was 10.3 years old. Over in eight years period, lowest and highest age standardized incidence rate was 64 (year 2001) and 235 (year 2006) cases per every one million person, respectively. Conclusion: Based on this paper’s results, and despite of our prospect, childhood cancer incidence rate in less than 19 year age in Fars province was similar to developed countries