An observational study to correlate arterial lactate level and peripheral perfusion index in context of tissue perfusion in sepsis

Background: In view of goal directed therapies, the predictive value of the course of peripheral perfusion parameters over time has not been studied. Moreover serial assessment of peripheral perfusion index (PI) can be more predictive for mortality when compared to a single assessment of peripheral perfusion. Successfully normalized PI (≥1.4) during treatment might be an indication to stop the resuscitation, whereas pursuing normalized PI (≥1.4) might not result in better outcomes compared with mild-to moderate PI impairment after a normalized arterial lactate level. Complementing arterial lactate assessment with PI during resuscitation can better identify the endpoint of resuscitation and patients at higher risk of adverse outcomes. By simple clinical assessment of peripheral perfusion immediately during and after resuscitation, clinicians will be able to discriminate patients at high risk for developing severe complications even in the rural setups. Methods: This prospective study was conducted on 100 patients admitted at Dr. Kiran C. Patel Medical College and Research Institute, over a period of 12months (Janury 2022 to December 2022). Patients of sepsis were selected on the basis of criteria for tissue hypoperfusion and classification of sepsis. Results: On statistical analysis, PI was found to have significant correlation with arterial lactate levels (P<0.001) in PI <1.4 sub-measurement and not in PI >1.4. SOFA score & metabolic parameters were also found to have statistical significance. Conclusions: We inferred that peripheral perfusion index monitoring could provide useful information to determine the possibility of hyperlactatemia in critically ill patients thus providing a noninvasive source of tissue-bed perfusion monitoring even in the absence of facilities and infrastructure to measure the lactate levels thereby providing a gross insight in the perfusion haemodynamics of the patients of sepsis even in the primary healthcare setups too

An alternative approach for construction of strata using quantified sensitivity level

The study is investigated on an alternative method for the construction of strata using sensitivity level when the samples are selected with simple random sampling with replacement (SRSWR) and the data are collected by scrambled optional randomization technique on the sensitive characters. Thus, the optional randomized response model , where k is a random variable having value 1 if the response is scrambled and 0 otherwise, was considered for finding out Approximate Optimum Strata Boundaries by minimizing the variance of the estimator  . The cum.   was proposed for finding out Approximate Optimum Strata Boundary in Neyman allocation for the optional scrambled response. This is applicable for wider classes of sampling design and estimators in stratification. The proposed rule on optional scrambled randomized response is efficient and can be used effectively for the construction of optimum strata boundary via Rectangular, Right triangular and Exponential distribution. 

Phenol as a Non-aqueous Solvent

1017-101

Electronic structure of spin 1/2 Heisenberg antiferromagnetic systems: Ba_2Cu(PO_4)_2 and Sr_2Cu(PO_4)_2

We have employed first principles calculations to study the electronic structure and magnetic properties of the low-dimensional phosphates, Ba2Cu(PO4)2 and Sr2Cu(PO4)2. Using the self-consistent tight-binding lin- earized muffin-tin orbital method and the Nth order muffin-tin orbital method, we have calculated the various intrachain as well as the interchain hopping parameters between the magnetic ions Cu2+ for both the com- pounds. We find that the nearest-neighbor intrachain hopping t is the dominant interaction suggesting the compounds to be indeed one dimensional. Our analysis of the band dispersion, orbital projected band struc- tures, and the hopping parameters confirms that the Cu2+-Cu2+ super-super exchange interaction takes place along the crystallographic b direction mediated by O-P-O. We have also analyzed in detail the origin of short-range exchange interaction for these systems. Our ab initio estimate of the ratio of the exchange inter- action of Sr2Cu(PO4)2 to that of Ba2Cu(PO4)2 compares excellently with available experimental results.Comment: 6 pages, 4 figure

Antimicrobial susceptibility pattern of bacterial isolates in patients of chronic suppurative otitis media in a tertiary care hospital in India

Background: Chronic suppurative otitis media (CSOM) is a massive public health problem in developing countries like India, especially among low socio-economic class because of malnutrition, overcrowding, poor hygiene, inadequate health care and recurrent upper respiratory tract infections. CSOM cases unless managed effectively may land into various complications such as persistent otorrhoea, hearing impairment, mastoiditis, labyrinthitis, facial nerve paralysis to more serious intracranial abscesses.Methods: The study was carried out in a tertiary care hospital from January 2017 to December 2017 with an aim to determine the microbiological profile of ear discharge in patients suffering from CSOM and their antimicrobial susceptibility pattern using Kirby Bauer disc diffusion method.Results: Out of 630 samples processed, 407 (64.6%) samples were culture positive. Most common organism isolated was Pseudomonas spp. (43.2%) followed by S. aureus (39.1%). Most of isolates recovered were multidrug resistant.Conclusions: Management of CSOM consists mainly of eradicating infection and closure of tympanic membrane. Periodic monitoring of bacterial isolates and their antibiotic susceptibility pattern is necessary for administering appropriate antibiotics as empirical treatment and also helps in reducing the potentially disabling and fatal complications of CSOM

On a Raychaudhuri equation for hot gravitating fluids

We generalize the Raychaudhuri equation for the evolution of a self gravitating fluid to include an Abelian and non-Abelian hybrid magneto fluid at a finite temperature. The aim is to utilize this equation for investigating the dynamics of astrophysical high temperature Abelian and non-Abelian plasmas.Comment: 13 pages, Invited contribution to Pramana special issue dedicated to A.K. Raychaudhuri, "The Raychaudhuri equation and its role in Modern Cosmology". Pramana style files include

Incoherent Effect of Fe and Ni Substitutions in the Ferromagnetic-Insulator La0.6Bi0.4MnO3+d

A comparative study of the effect of Fe and Ni doping on the bismuth based perovskite La0.6Bi0.4MnO3.1, a projected spintronics magnetic semiconductor has been carried out. The doped systems show an expressive change in magnetic ordering temperature. However, the shifts in ferromagnetic transition (TC) of these doped phases are in opposite direction with respect to the parent phase TC of 115 K. The Ni-doped phase shows an increase in TC ~200 K, whereas the Fe-doped phase exhibits a downward shift to TC~95 K. Moreover, the Fe-doped is hard-type whereas the Ni-doped compound is soft-type ferromagnet. It is observed that the materials are semiconducting in the ferromagnetic phase with activation energies of 77 & 82 meV for Fe & Ni-doped phases respectively. In the presence of external magnetic field of 7 Tesla, they exhibit minor changes in the resistivity behaviours and the maximum isothermal magnetoresistance is around -20 % at 125 K for the Ni-phase. The results are explained on the basis of electronic phase separation and competing ferromagnetic and antiferromagnetic interactions between the various mixed valence cations.Comment: 18 pages including figure

Phenomenology of Noncommutative Field Theories

Experimental limits on the violation of four-dimensional Lorentz invariance imply that noncommutativity among ordinary spacetime dimensions must be small. In this talk, I review the most stringent bounds on noncommutative field theories and suggest a possible means of evading them: noncommutativity may be restricted to extra, compactified spatial dimensions. Such theories have a number of interesting features, including Abelian gauge fields whose Kaluza-Klein excitations have self couplings. We consider six-dimensional QED in a noncommutative bulk, and discuss the collider signatures of the model.Comment: 7 pages RevTeX, 4 eps figures, Invited plenary talk, IX Mexican Workshop on Particles and Fields, November 17-22, 2003, Universidad de Colima, Mexic

Spin Dynamics near the Superconductor-to-Insulator Transition in Impurity-Doped YBa2Cu4O8

We studied low-frequency spin dynamics near the impurity-induced superconductor-to-insulator transition for underdoped high-Tc superconductor YBa2(Cu1-xMx)4O8 (M=Ni, Zn) using the Cu nuclear quadrupole resonance (NQR) spin-echo technique. We observed remarkable suppression of the normal-state pseudo spin-gap and a loss of Cu NQR spectrum intensity at low temperatures around the critical impurity concentration.Comment: 6 pages, 4 figures. To be published in J. Phys. Soc. Jpn. Vol.70, No.7 (2001