I frammenti di mummy cover dell’Egyptian corner dell’Università degli Studi di Pavia

The paper presents for the first time to the public some wooden fragments of an ancient Egyptian ‘mummy cover’, kept in the ‘Egyptian Corner’ of the University of Pavia Archaeology Museum (Italy). The fragments, belonging to an original ancient Egyptian artefact which dates back to the end of the New Kingdom, are here published after a restoration performed by Chiara Argentino in 2018. The restoration was aimed at better understanding the artefacts themselves and their role within the Egyptological collection of the University of Pavia. Fungal contamination of the fragments was assessed before the restoration with the support of the laboratory of mycology of Pavia University (DSTA)

Прототип автоматической системы экстренного торможения транспортного средства

Разработка, сборка и испытание прототипа автономной системы экстренного торможения транспортного средства на основе 8-битного микроконтроллера AVR типа ATmega16 и ультразвукового дальномера HC-SR04, срабатывающей при приближении к объекту на расстояние около 10 см. Программу микроконтроллера будет написана на языке Си с использованием программатора STK-500.Development, assembly and testing of the prototype of the autonomous emergency braking system of a vehicle based on the 8-bit AVR microcontroller type ATmega16 and ultrasonic rangefinder HC-SR04, triggered when approaching the object at a distance of about 10 cm. The program of the microcontroller will be written in C language using the programmer STK -500

Prospective validation of the CLIP score: a new prognostic system for patient with cirrhosis and hepatocellular carcinoma

Prognosis of patients with cirrhosis and hepatocellular carcinoma (HCC) depends on both residual liver function and tumor extension. The CLIP score includes Child-Pugh stage, tumor morphology and extension, serum alfa-fetoprotein (AFP) levels, and portal vein thrombosis. We externally validated the CLIP score and compared its discriminatory ability and predictive power with that of the Okuda staging system in 196 patients with cirrhosis and HCC prospectively enrolled in a randomized trial. No significant associations were found between the CLIP score and the age, sex, and pattern of viral infection. There was a strong correlation between the CLIP score and the Okuda stage, As of June 1999, 150 patients (76.5%) had died. Median survival time was 11 months, overall, and it was 36, 22, 9, 7, and 3 months for CLIP categories 0, 1, 2, 3, and 4 to 6, respectively. In multivariate analysis, the CLIP score had additional explanatory power above that of the Okuda stage. This was true for both patients treated with locoregional therapy or not. A quantitative estimation of 2-year survival predictive power showed that the CLIP score explained 37% of survival variability, compared with 21% explained by Okuda stage. In conclusion, the CLIP score, compared with the Okuda staging system, gives more accurate prognostic information, is statistically more efficient, and has a greater survival predictive power. It could be useful in treatment planning by improving baseline prognostic evaluation of patients with RCC, and could be used in prospective therapeutic trials as a stratification variable, reducing the variability of results owing to patient selection

Il patrimonio del Sistema Museale di Ateneo a disposizione di tutti: la Digital Library dell’Università di Pavia

Si descrive il progetto Digital Library dell'Università di Pavia in rapporto alla valorizzazione delle collezioni museali dell'Ateneo

Il morbo di Violetta. Il patrimonio storico legato alla medicina per affrontare temi di attualità

Per ricordare, nel centenario della morte, Carlo Forlanini (1847-1918), che ideò il primo metodo di cura realmente efficace della tubercolosi, è stata allestita a Pavia una mostra tesa a inquadrare la figura del grande clinico in una storia della malattia raccontata in chiave multidisciplinare. Conferenze legate alla mostra hanno permesso di approfondire temi storico-letterari e di attualità scientifica

Meningeal Melanomatosis: A Challenge for Timely Diagnosis

Neoplastic meningitis is a central nervous system complication that occurs in 3–5% of patients with cancer. Although most commonly seen in patients with disseminated disease, in a small percentage of patients, it may be the initial manifestation of cancer or even primitive in origin. In the absence of cancer history, the diagnosis of neoplastic meningitis may be challenging even for expert neurologists. Prognosis is poor, with a median overall survival of weeks from diagnosis. In the retrospective study herein, we described three cases of meningeal melanomatosis in patients without previous cancer history. The patients were diagnosed with significant delay (17 to 47 weeks from symptom onset) mainly due to the deferral in performing the appropriate testing. Even when the diagnosis was suspected, investigations by MRI, cerebrospinal fluid, or both proved at times unhelpful for confirmation. Prognosis was dismal, with a median survival of 4 weeks after diagnosis. Our observations are a cue to analyze the main pitfalls in the diagnosis of neoplastic meningitis in patients without cancer history and emphasize key elements that may facilitate early diagnosis