36 research outputs found
Experiências psíquicas de mulheres frequentadoras da rede pública de saúde em Teresina (PI, Brasil)
One Health: The global challenge of epidemic and endemic leishmaniasis
'One Health' proposes the unification of medical and veterinary sciences with the establishment of collaborative ventures in clinical care, surveillance and control of cross-species disease, education, and research into disease pathogenesis, diagnosis, therapy and vaccination. The concept encompasses the human population, domestic animals and wildlife, and the impact that environmental changes ('environmental health') such as global warming will have on these populations. Visceral leishmaniasis is a perfect example of a small companion animal disease for which prevention and control might abolish or decrease the suffering of canine and human patients, and which aligns well with the One Health approach. In this review we discuss how surveillance for leishmaniases is undertaken globally through the control of anthroponootic visceral leishmaniasis (AVL) and zoonotic visceral leishmaniasis (ZVL). The ZVL epidemic has been managed to date by the culling of infected dogs, treatment of human cases and control of the sandfly vector by insecticidal treatment of human homes and the canine reservoir. Recently, preventive vaccination of dogs in Brazil has led to reduction in the incidence of the canine and human disease. Vaccination permits greater dog owner compliance with control measures than a culling programme. Another advance in disease control in Africa is provided by a surveillance programme that combines remote satellite sensing, ecological modelling, vector surveillance and geo-spatial mapping of the distribution of vectors and of the animal-to-animal or animal-to-human pathogen transmission. This coordinated programme generates advisory notices and alerts on emerging infectious disease outbreaks that may impede or avoid the spreading of visceral leishmaniasis to new areas of the planet as a consequence of global warming
Activity of oil-formulated Beauveria bassiana against Triatoma sordida in peridomestic areas in central Brazil
Evaluating the effectiveness of the customized Unna boot when treating patients with venous ulcers*
Improved cider fermentation performance and quality with newly generated Saccharomyces cerevisiae × Saccharomyces eubayanus hybrids
Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva
Recommended from our members
Benchmarking edge computing devices for grape bunches and trunks detection using accelerated object detection single shot multibox deep learning models
Purpose: Visual perception enables robots to perceive the environment. Visual data is processed using computer vision algorithms that are usually time-expensive and require powerful devices to process the visual data in real-time, which is unfeasible for open-field robots with limited energy. This work benchmarks the performance of different heterogeneous platforms for object detection in real-time. This research benchmarks three architectures: embedded GPU-Graphical Processing Units (such as NVIDIA Jetson Nano 2 GB and 4 GB, and NVIDIA Jetson TX2), TPU-Tensor Processing Unit (such as Coral Dev Board TPU), and DPU-Deep Learning Processor Unit (such as in AMD-Xilinx ZCU104 Development Board, and AMD-Xilinx Kria KV260 Starter Kit).
Methods: The authors used the RetinaNet ResNet-50 fine-tuned using the natural VineSet dataset. After the trained model was converted and compiled for target-specific hardware formats to improve the execution efficiency.
Conclusions and Results: The platforms were assessed in terms of performance of the evaluation metrics and efficiency (time of inference). Graphical Processing Units (GPUs) were the slowest devices, running at 3 FPS to 5 FPS, and Field Programmable Gate Arrays (FPGAs) were the fastest devices, running at 14 FPS to 25 FPS. The efficiency of the Tensor Processing Unit (TPU) is irrelevant and similar to NVIDIA Jetson TX2. TPU and GPU are the most power-efficient, consuming about 5 W. The performance differences, in the evaluation metrics, across devices are irrelevant and have an F1 of about 70 % and mean Average Precision (mAP) of about 60 %
Activity of oil-formulated Beauveria bassiana against Triatoma sordida in peridomestic areas in central Brazil
Field tests were carried out during the rainy season of 2001/2002 in São Luís de Montes Belos, Goiás, Brazil, to evaluate the potential of the entomopathogenic fungus, Beauveria bassiana, against peridomestic Triatoma sordida. An oil-water formulation of the isolate CG 14 (Embrapa) was applied in triatomine infested hen houses of four farms at a final concentration of 10(6) conidia/cm². Numbers of T. sordida decreased over the next 25 days, after application of the fungus, and B. bassiana developed on dead insects in one hen house. A high number of B. bassiana colonies was detected in substrates collected in treated hen houses 24 h after application of CG 14. In the following three months the presenceof B. bassiana declined to values found before treatment
Goat milk with and without increased concentrations of lysozyme improves repair of intestinal cell damage induced by enteroaggregative <it>Escherichia coli</it>
Abstract Background Enteroaggregative Escherichia coli (EAEC) causes diarrhea, malnutrition and poor growth in children. Human breast milk decreases disease-causing bacteria by supplying nutrients and antimicrobial factors such as lysozyme. Goat milk with and without human lysozyme (HLZ) may improve the repair of intestinal barrier function damage induced by EAEC. This work investigates the effect of the milks on intestinal barrier function repair, bacterial adherence in Caco-2 and HEp-2 cells, intestinal cell proliferation, migration, viability and apoptosis in IEC-6 cells in the absence or presence of EAEC. Methods Rat intestinal epithelial cells (IEC-6, ATCC, Rockville, MD) were used for proliferation, migration and viability assays and human colon adenocarcinoma (Caco-2, ATCC, Rockville, MD) and human larynx carcinoma (HEp-2, ATCC, Rockville, MD) cells were used for bacterial adhesion assays. Goats expressing HLZ in their milk were generated and express HLZ in milk at concentration of 270 μg/ml . Cells were incubated with pasteurized milk from either transgenic goats expressing HLZ or non-transgenic control goats in the presence and absence of EAEC strain 042 (O44:H18). Results Cellular proliferation was significantly greater in the presence of both HLZ transgenic and control goat milk compared to cells with no milk. Cellular migration was significantly decreased in the presence of EAEC alone but was restored in the presence of milk. Milk from HLZ transgenic goats had significantly more migration compared to control milk. Both milks significantly reduced EAEC adhesion to Caco-2 cells and transgenic milk resulted in less colonization than control milk using a HEp-2 assay. Both milks had significantly increased cellular viability as well as less apoptosis in both the absence and presence of EAEC. Conclusions These data demonstrated that goat milk is able to repair intestinal barrier function damage induced by EAEC and that goat milk with a higher concentration of lysozyme offers additional protection.</p