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Polychronicity in top management teams: The impact on strategic decision processes and performance of new technology ventures
This study focuses on polychronicity as a cultural dimension of top management teams (TMTs). TMT polychronicity is the extent to which team members mutually prefer and tend to engage in multiple tasks simultaneously or intermittently instead of one at a time and believe that this is the best way of doing things. We explore the impact of TMT polychronicity on strategic decision speed and comprehensiveness and, subsequently, its effect on new venture financial performance. Contrary to popular time-management principles advocating task prioritization and focused sequential execution, we found that TMT polychronicity has a positive effect on firm performance in the context of dynamic unanalyzable environments. This effect is partially mediated by strategic decision speed and comprehensiveness. Our study contributes to research on strategic leadership by focusing on a novel value-based characteristic of the TMT (polychronicity) and by untangling the decision-making processes that relate TMT characteristics and firm performance. It also contributes to the attention-based view of the firm by positioning polychronicity as a new type of attention structure
Second phalanx shortening osteotomy. An innovative technique for long second toe syndrome
AbstractLong second-toe syndrome, although frequent and disabling, has been little described. Current surgical techniques often lead to loss of function. Based on anatomical and biomechanical observations, the present study reports a second phalanx shortening osteotomy technique. The procedure is relatively non-invasive, involving self-stabilizing segment resection osteotomy of the second phalanx. Results for the first 23 feet undergoing the procedure were analyzed retrospectively. Assessment comprised clinical examination, radiography and AOFAS and FAAM scores. Mean follow-up was 19±9.9months. Second phalanx shortening osteotomy proved reliable, respecting the biomechanics of the toe
Evidence for gapped spin-wave excitations in the frustrated Gd2Sn2O7 pyrochlore antiferromagnet from low-temperature specific heat measurements
We have measured the low-temperature specific heat of the geometrically
frustrated pyrochlore Heisenberg antiferromagnet Gd2Sn2O7 in zero magnetic
field. The specific heat is found to drop exponentially below approximately 350
mK. This provides evidence for a gapped spin-wave spectrum due to an anisotropy
resulting from single ion effects and long-range dipolar interactions. The data
are well fitted by linear spin-wave theory, ruling out unconventional low
energy magnetic excitations in this system, and allowing a determination of the
pertinent exchange interactions in this material
Ins1 (Cre) knock-in mice for beta cell-specific gene recombination.
AIMS/HYPOTHESIS: Pancreatic beta cells play a central role in the control of glucose homeostasis by secreting insulin to stimulate glucose uptake by peripheral tissues. Understanding the molecular mechanisms that control beta cell function and plasticity has critical implications for the pathophysiology and therapy of major forms of diabetes. Selective gene inactivation in pancreatic beta cells, using the Cre-lox system, is a powerful approach to assess the role of particular genes in beta cells and their impact on whole body glucose homeostasis. Several Cre recombinase (Cre) deleter mice have been established to allow inactivation of genes in beta cells, but many show non-specific recombination in other cell types, often in the brain.
METHODS: We describe the generation of Ins1 (Cre) and Ins1 (CreERT2) mice in which the Cre or Cre-oestrogen receptor fusion protein (CreERT2) recombinases have been introduced at the initiation codon of the Ins1 gene.
RESULTS: We show that Ins1 (Cre) mice induce efficient and selective recombination of floxed genes in beta cells from the time of birth, with no recombination in the central nervous system. These mice have normal body weight and glucose homeostasis. Furthermore, we show that tamoxifen treatment of adult Ins1 (CreERT2) mice crossed with Rosa26-tdTomato mice induces efficient recombination in beta cells.
CONCLUSIONS/INTERPRETATION: These two strains of deleter mice are useful new resources to investigate the molecular physiology of pancreatic beta cells
Critical disorder effects in Josephson-coupled quasi-one-dimensional superconductors
Effects of non-magnetic randomness on the critical temperature T_c and
diamagnetism are studied in a class of quasi-one dimensional superconductors.
The energy of Josephson-coupling between wires is considered to be random,
which is typical for dirty organic superconductors. We show that this
randomness destroys phase coherence between the wires and T_c vanishes
discontinuously when the randomness reaches a critical value. The parallel and
transverse components of the penetration depth are found to diverge at
different critical temperatures T_c^{(1)} and T_c, which correspond to
pair-breaking and phase-coherence breaking. The interplay between disorder and
quantum phase fluctuations results in quantum critical behavior at T=0,
manifesting itself as a superconducting-normal metal phase transition of
first-order at a critical disorder strength.Comment: 4 pages, 2 figure
Production of PHB from Chicory Roots - Comparison of Three Cupriavidus necator Strains
Chicory roots from hydroponic salad cultivation are an abundant food residue in Navarra (Spain) that are underutilized to date. Aiming at a holistic utilization of resources, we report here the first process using chicory root hydrolysate for the production of poly([R]-3-hydroxybutyrate) (PHB). The polymer can be used for packaging material made for the locally produced vegetables.
In the first step, we developed a pre-treatment process to obtain a hydrolysate, which contained 34 g L-1 sugars and 0.7 g L-1 total Kjeldahl nitrogen. This hydrolysate was used as fermentation substrate for three PHB-producing strains. Cupriavidus necator DSM 428 reached a dry biomass concentration of 11.3 g L-1 with a PHB content of 66 % in dry mass within 5 days. C. necator DSM 531 yielded 3.5 g L-1 dry biomass containing 46 % PHB within the same period. C. necator DSM 545 was superior over the other two in that 14.0 g L-1 of biomass containing 78 % PHB after only 3 days were obtained. These results show that even within the same species, the productivities on natural substrates are very different. The produced polymers were extracted using chloroform, and several thermo-physical parameters are in good accordance with published data. Overall, our holistic approach and the encouraging results prove that chicory roots are a viable fermentation substrate for PHB-production.This work was conducted as a part of the LEAD-ERA Project CARBIO, which was financed by the Basque Goverment and co-financed by the European Regional Development Fund (ERDF) of the European Union
Quantum spin fluctuations in the dipolar Heisenberg-like rare earth pyrochlores
The magnetic pyrochlore oxide materials of general chemical formula R2Ti2O7
and R2Sn2O7 (R = rare earth) display a host of interesting physical behaviours
depending on the flavour of rare earth ion. These properties depend on the
value of the total magnetic moment, the crystal field interactions at each rare
earth site and the complex interplay between magnetic exchange and long-range
dipole-dipole interactions. This work focuses on the low temperature physics of
the dipolar isotropic frustrated antiferromagnetic pyrochlore materials.
Candidate magnetic ground states are numerically determined at zero temperature
and the role of quantum spin fluctuations around these states are studied using
a Holstein-Primakoff spin wave expansion to order 1/S. The results indicate the
strong stability of the proposed classical ground states against quantum
fluctuations. The inclusion of long range dipole interactions causes a
restoration of symmetry and a suppression of the observed anisotropy gap
leading to an increase in quantum fluctuations in the ground state when
compared to a model with truncated dipole interactions. The system retains most
of its classical character and there is little deviation from the fully ordered
moment at zero temperature.Comment: Latex2e, 18 pages, 4 figures, IOP forma
Pair-breaking quantum phase transition in superconducting nanowires
A quantum phase transition (QPT) between distinct ground states of matter is
a wide-spread phenomenon in nature, yet there are only a few experimentally
accessible systems where the microscopic mechanism of the transition can be
tested and understood. These cases are unique and form the experimentally
established foundation for our understanding of quantum critical phenomena.
Here we report the discovery that a magnetic-field-driven QPT in
superconducting nanowires - a prototypical 1d-system - can be fully explained
by the critical theory of pair-breaking transitions characterized by a
correlation length exponent and dynamic critical exponent . We find that in the quantum critical regime, the electrical
conductivity is in agreement with a theoretically predicted scaling function
and, moreover, that the theory quantitatively describes the dependence of
conductivity on the critical temperature, field magnitude and orientation,
nanowire cross sectional area, and microscopic parameters of the nanowire
material. At the critical field, the conductivity follows a
dependence predicted by phenomenological scaling theories and more recently
obtained within a holographic framework. Our work uncovers the microscopic
processes governing the transition: The pair-breaking effect of the magnetic
field on interacting Cooper pairs overdamped by their coupling to electronic
degrees of freedom. It also reveals the universal character of continuous
quantum phase transitions.Comment: 22 pages, 5 figure
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