Using multiphase fluid flow modeling and time-lapse electromagnetics to improve 4D monitoring of CO 2 in an EOR reservoir

Understanding the changes in the saturation within a reservoir undergoing enhanced oil recovery (EOR) is crucial to optimizing production. We debut a novel, multiphase fluid flow modelling code, TOGA, to assist in modeling gas, oil, and water phases within the reservoir, and combine its output with time-lapse Depth to Surface Resistivity data in a case study involving an EOR reservoir. The results show the potential for combining the two methods to improve our understanding of reservoir saturation over an extended period of time

Reporting and dealing with missing quality of life data in RCTs : has the picture changed in the last decade?

Peer reviewedPublisher PD

The poetry of Guy Butler

[From the introduction]: Guy Butler, born in Cradock on 21 January 1918, was a serious poet. Nearly a third of his poems are about death or loss, and many of the rest about parting failure, or difficult self-denial. His poetry is generally thoughtful and responsible to a deep religious vision. Of the ninety poems published between 1939 and 1979 the finest are those written between 1943 and 1963, from “Syrian Spring” to “Sweetwater.” The best poems cluster like moons round “On First Seeing Florence,” which is a major poem seldom given its rightful attention

Lung cancer in Hong Kong Chinese: mortality and histological types, 1960-1972.

Age-adjusted mortality from lung cancer rose rapidly in both males and females in Hong Kong from 1960-1972. The relative frequency of epidermoid carcinoma increased in male bronchial biopsies but not in lung biopsies, resections, or autopsies; there was a decline in small-cell anaplastic carcinoma. In both males and females the ratio of Kreyberg Group I (epidermoid and small-cell anaplastic) to Group II (adenocarcinoma and carcinoid) tumours did not increase, despite an 80% rise in mortality from lung cancer. Adenocarcinoma was the most common type in females, despite the high mortality from lung cancer. It is speculated that cigarette smoking might produce a different pattern of histological types among Hong Kong Chinese, or that additional aetiological factors may be operating there

Determining information for inclusion in a decision-support intervention for clinical trial participation : A modified Delphi approach

Peer reviewedPostprin

Latitude dependence of co-rotating shock acceleration

Energetic particle observations in the outer heliosphere (approx 12 A. U.) by the LECP instruments on the Voyager 1 and Voyager 2 spacecraft are discussed that show a definite latitude dependence of the number and intensity of particle enhancements produced by corotating interplanetary regions during an interval when no solar energetic particle events were observed. The particle enhancements are fewer in number and less intense at higher (approx 20 deg.) heliolatitudes. However, the similar spectral shapes of the accelerated particles at the two spacecraft indicate that the acceleration process is the same at the two latitudes, but less intense at the higher latitude

Cytotoxic antibody in acute myeloblastic leukaemia during immunotherapy: lack of tumour specificity.

Cytotoxic antibodies to antigens specific for leukaemic myeloblasts have been sought in the serum of patients with acute myeloblastic leukaemia treated by immunotherapy with irradiated allogeneic myeloblasts and BCG. Assays of complement- and K-cell-mediated activity were used. Cytotoxicity to allogeneic myeloblasts was detected in both assays. When sera from 15 patients, taken at various times during immunotherapy, were systematically tested against a panel of 5 myeloblasts, the following patterns emerged: 1. No antibody was cytotoxic against all myeloblasts of the panel in either the K-cell or complement-dependent assay. However, all myeloblasts of the panel were lysed by a number of sera. 2. Cytotoxic antibody was detected as often against a panel of lymphocytes from healthy donors as against the panel of allogeneic myeloblasts. 3. Fresh and cryopreserved myeloblasts were equally susceptible to lysis in both assays. 4. Experiments failed to demonstrate any deterioration of cytotoxic antibody on storage. 5. The number of K-cell-revealed cytotoxic antisera increased with length of immunotherapy. This pattern was not apparent for antibodies revealed by complement. 6. No instance of cytotoxicity in either assay was seen when serum was tested against 12 autologous myeloblasts. It is considered that cytotoxic antibody detected with allogeneic myeloblasts is probably directed against HLA antigens common to immunizing and test target myeloblasts and target lymphocytes

Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer

UCAN Cancer Charity (www.ucanhelp.org.uk) and MacMillan Cancer Charity (www.macmillan.org.uk) helped design and conduct the study.Peer reviewedPostprin