209 research outputs found
Forest Conversion and Degradation in Papua New Guinea 1972-2002
Quantifying forest change in the tropics is important because of the role these forests play in the conservation of biodiversity and the global carbon cycle. One of the world's largest remaining areas of tropical forest is located in Papua New Guinea. Here we show that change in its extent and condition has occurred to a greater extent than previously recorded. We assessed deforestation and forest degradation in Papua New Guinea by comparing a land-cover map from 1972 with a land-cover map created from nationwide high-resolution satellite imagery recorded since 2002. In 2002 there were 28,251,967 ha of tropical rain forest. Between 1972 and 2002, a net 15 percent of Papua New Guinea's tropical forests were cleared and 8.8 percent were degraded through logging. The drivers of forest change have been concentrated within the accessible forest estate where a net 36 percent were degraded or deforested through both forestry and nonforestry processes. Since 1972, 13 percent of upper montane forests have also been lost. We estimate that over the period 1990–2002, overall rates of change generally increased and varied between 0.8 and 1.8 percent/yr, while rates in commercially accessible forest have been far higher—having varied between 1.1 and 3.4 percent/yr. These rates are far higher than those reported by the FAO over the same period. We conclude that rapid and substantial forest change has occurred in Papua New Guinea, with the major drivers being logging in the lowland forests and subsistence agriculture throughout the country with comparatively minor contributions from forest fires, plantation establishment, and mining
Development and Validation of a Multi-domain Multimorbidity Resilience Index for an Older Population: Results from the Baseline Canadian Longitudinal Study on Aging
Background Multimorbidity is recognized as a major public health issue that increases with age and affects approximately two-thirds of older people in Canada, the US, Australia and many European countries. This study develops and tests a three domain (functional, social and psychological) multimorbidity resilience composite index based on a previously developed lifecourse model of multimorbidity resilience, incorporating measures of adversity and positive adaptation. The criterion validity of the measure is demonstrated by means of an analysis of key outcome variables drawn from the literature.
Methods We used the baseline data from the Comprehensive Cohort of the Canadian Longitudinal Study on Aging. Associations of functional, social, psychological as well as total resilience with two health utilization and three illness context outcome variables were examined using logistic regression analyses, adjusted for age, gender, marital status, income, education, region, and number of chronic conditions.
Results The sample included all 6771 Canadian adults aged 65 or older (mean age 73.0, 57% women) who reported two or more of 27 possible chronic conditions. Total resilience was associated with: perceived health (OR = 1.68, CI 1.59–1.77); sleep quality (OR = 1.34, CI 1.30–1.38); perceived pain (OR = 0.80, CI 0.77–0.83); hospital overnight stays (OR = 0.87, CI 0.83–0.91); and emergency department visits (OR = 0.90, CI 0.87–0.94)., after adjusting for socio-demographic factors, and number of chronic conditions. These associations were similar for the unadjusted models, as well as for the functional, social and psychological resilience sub-indices.
Conclusions Combining components of adversity and positive adaptation within functional, social and psychological domains produces a measure of multimorbidity resilience that is associated with more positive health outcomes. Several implications of a composite multimorbidity resilience measure for clinical practice are identified. This measure can be replicated using measures found in other secondary health data sets. Future validation using longitudinal data is warranted
Concentrations of Polychlorinated Biphenyls (PCB’s), Chlorinated Pesticides, and Heavy Metals and Other Elements in Tissues of Belugas, Delphinapterus leucas, from Cook Inlet
Tissues from Cook Inlet beluga whales, Delphinapterus leucas, that were collected as part of the Alaska Marine Mammal Tissue Archival Project were analyzed for polychlorinated biphenyls (PCB’s), chlorinated pesticides, and heavy metals and other elements. Concentrations of total PCB’s (ΣPCB’s), total DDT (ΣDDT), chlordane compounds, hexachlorobenzene (HCB), dieldrin, mirex, toxaphene, and hexachlorocyclohexane (HCH) measured in Cook Inlet beluga blubber were compared with those reported for belugas from two Arctic Alaska locations (Point Hope and Point Lay), Greenland, Arctic Canada, and the highly contaminated stock from the St. Lawrence estuary in eastern Canada. The Arctic and Cook Inlet belugas had much lower concentrations (ΣPCB’s and ΣDDT were an order of magnitude lower) than those found in animals from the St. Lawrence estuary. The Cook Inlet belugas had the lowest concentrations of all (ΣPCB’s aver-aged 1.49 ± 0.70 and 0.79 ± 0.56 mg/kg wet mass, and ΣDDT averaged 1.35 ± 0.73 and 0.59 ± 0.45 mg/kg in males and females, respectively). Concentrations in the blubber of the Cook Inlet males were significantly lower than those found in the males of the Arctic Alaska belugas (ΣPCB’s and ΣDDT were about half). The lower levels in the Cook Inlet animals might be due to differences in contaminant sources, food web differences, or different age distributions among the animals sampled. Cook Inlet males had higher mean and median concentrations than did females, a result attributable to the transfer of these compounds from mother to calf during pregnancy and during lactation. Liver concentrations of cadmium and mercury were lower in the Cook Inlet belugas (most cadmium values were <1 mg/kg and mercury values were 0.704–11.42 mg/kg wet mass), but copper levels were significantly higher in the Cook Inlet animals (3.97–123.8 mg/kg wet mass) than in Arctic Alaska animals and similar to those reported for belugas from Hudson Bay. Although total mercury levels were the lowest in the Cook Inlet population, methylmercury concentrations were similar among all three groups of the Alaska animals examined (0.34–2.11 mg/kg wet mass). As has been reported for the Point Hope and Point Lay belugas, hepatic concentrations of silver were r
Policy options for the world’s primary forests in multilateral environmental agreements
We identify policies that would provide a solid foundation in key international negotiations to ensure that primary forests persist into the 21st Century. A novel compilation of primary forest cover and other data revealed that protection of primary forests is a matter of global concern being equally distributed between developed and developing countries. Almost all (98%) of primary forest is found within 25 countries with around half in five developed ones (USA, Canada, Russia, Australia, and NZ). Only approximate to 22% of primary forest is found in IUCN Protected Areas Categories I-VI, which is approximately 5% of preagriculture natural forest cover. Rates of deforestation and forest degradation are rapid and extensive, and the long-term integrity of primary forest cannot be assumed. We recommend four new actions that could be included in climate change, biodiversity, and sustainable development negotiations: (1) recognize primary forests as a matter of global concern within international negotiations; (2) incorporate primary forests into environmental accounting; (3) prioritize the principle of avoided loss; and (4) universally accept the important role of indigenous and community conserved areas. In the absence of specific policies for primary forest protection, their unique biodiversity values and ecosystem services will continue to erode
Transcriptional regulation by nicotine in dopaminergic neurons
Dopaminergic neurons in the substantia nigra pars compacta (SNc) degenerate in Parkinson's disease. These neurons robustly express several nicotinic acetylcholine receptor (nAChR) subtypes. Smoking appears to be neuroprotective for Parkinson's disease but the mechanism is unknown. To determine whether chronic nicotine-induced changes in gene expression contribute to the neuroprotective effects of smoking, we develop methods to measure the effect of prolonged nicotine exposure on the SNc neuronal transcriptome in an unbiased manner. Twenty neurons were collected using laser-capture microscopy and transcriptional changes were assessed using RNA deep sequencing. These results are the first whole-transcriptome analyses of chronic nicotinic treatment in SNc neurons. Overall, 129 genes were significantly regulated: 67 upregulated, 62 downregulated. Nicotine-induced relief of endoplasmic reticulum (ER) stress has been postulated as a potential mechanism for the neuroprotective effects of smoking. Chronic nicotine did not significantly affect the expression of ER stress-related genes, nor of dopamine-related or nAChR genes, but it did modulate expression of 129 genes that could be relevant to the neuroprotective effects of smoking, including genes involved in (1) the ubiquitin-proteasome pathway, (2) cell cycle regulation, (3) chromatin modification, and (4) DNA binding and RNA regulation. We also report preliminary transcriptome data for single-cell dopaminergic and GABAergic neurons isolated from midbrain cultures. These novel techniques will facilitate advances in understanding the mechanisms taking place at the cellular level and may have applications elsewhere in the fields of neuroscience and molecular biology. The results give an emerging picture of the role of nicotine on the SNc and on dopaminergic neurons
Exile Vol. XVI No. 2
PREFACE 3
ESSAY
Observations At The Gap by Paul A. Dimitruk 4
Those Who Choose Words By Keith McWalter 5-6
On Victoria\u27s England by Paul A. Dimitruk 7-8
Facts Are The Enemy of Truth by Nancy Gutierrez
FICTION
Harmon by Barbara Mackey 22-25
Pilgrimage by Keith McWalter 35-44
ARTWORK
by Wandi Solez: 6, 15, 23, 27
by Ken Wernz 10
by Stephen Swift 11
by Laura M. Hyslop 12
by Skip Staudt 19
by W. A. Hoffman 25
by Mary Ann Kowaski 34
by Jo Ann Orgo 40
PHOTOGRAPHY
by Roger Block 16
by Tim Heath- all other
POETRY
My Poems by Susan Hallock 13
Counter-Fugue At Six-Thirty by Sherry Stodola 14-16
Apple Tree Poem by Darby Williams 17
When Snow Falls Into A Pond by Bruce Kidd 17
Woman-Man by Darby Williams 18
Transcendence by Wandi Solez 20
Paris Reflection by Wandi Solez 20
A Sleepless Night In Valencia, Spain by Wandi Solez 21
# 319 by Wandi Solez 21
Strange Lady by John Gillespie 26
Strange Lady II by John Gillespie 26
Where The Hell Is Rembrandt? by John Loveland 26
Years Ago by John Whitt 29
I\u27ve Finished Growing Now by Keith McWalter 29
Charisma by John Whitt 30
I Thought Of Cutting by John Loveland 31
Make Me Eat Peanut Butter by Fred Walton 31
The Cat by John Loveland 32
On The Rim by John Whitt 33
Undercurrent by Keith McWalter 33
Cover: Gail Lutsch
Layouts: Keith McWalte
Is the Macronutrient Intake of Formula-Fed Infants Greater Than Breast-Fed Infants in Early Infancy?
Faster weight gain early in infancy may contribute to a greater risk of later obesity in formula-fed compared to breast-fed infants. One potential explanation for the difference in weight gain is higher macronutrient intake in formula-fed infants during the first weeks of life. A systematic review was conducted using Medline to assess the macronutrient and energy content plus volume of intake in breast-fed and formula-fed infants in early infancy. All studies from healthy, term, singleton infants reporting values for the composition of breast milk during the first month of life were included. The energy content of colostrum (mean, SEM: 53.6±2.5 kcal/100 mL), transitional milk (57.7±4.2 kcal/100 mL), and mature milk (65.2±1.1 kcal/100 mL) was lower than conventional infant formula (67 kcal/100 mL) on all days analyzed. The protein concentration of colostrum (2.5±0.2 g/100 mL) and transitional milk (1.7±0.1 g/100 mL) was higher than formula (1.4 g/100 mL), while the protein content of mature milk (1.3±0.1 g/100 mL) was slightly lower. Formula-fed infants consume a higher volume and more energy dense milk in early life leading to faster growth which could potentially program a greater risk of long-term obesity
The Spatial Evolution of Stellar Structures in the LMC/SMC
We present an analysis of the spatial distribution of various stellar
populations within the Large and Small Magellanic Clouds. We use optically
selected stellar samples with mean ages between ~9 and ~1000 Myr, and existing
stellar cluster catalogues to investigate how stellar structures form and
evolve within the LMC/SMC. We use two statistical techniques to study the
evolution of structure within these galaxies, the -parameter and the
two-point correlation function (TPCF). In both galaxies we find the stars are
born with a high degree of substructure (i.e. are highly fractal) and that the
stellar distribution approaches that of the 'background' population on
timescales similar to the crossing times of the galaxy (~80/150 Myr for the
SMC/LMC respectively). By comparing our observations to simple models of
structural evolution we find that 'popping star clusters' do not significantly
influence structural evolution in these galaxies. Instead we argue that general
galactic dynamics are the main drivers, and that substructure will be erased in
approximately the crossing time, regardless of spatial scale, from small
clusters to whole galaxies. This can explain why many young Galactic clusters
have high degrees of substructure, while others are smooth and centrally
concentrated. We conclude with a general discussion on cluster 'infant
mortality', in an attempt to clarify the time/spatial scales involved.Comment: 6 pages, conference contribution to IAU Symposium 256, van Loon J.T.
& Oliviera J.M., ed
Is the macronutrient intake of formula-fed infants greater than breast-fed infants in early infancy
Faster weight gain early in infancy may contribute to a greater risk of later obesity in formula-fed compared to breast-fed infants. One potential explanation for the difference in weight gain is higher macronutrient intake in formula-fed infants during the first weeks of life. A systematic review was conducted using Medline to assess the macronutrient and energy content plus volume of intake in breast-fed and formula-fed infants in early infancy. All studies from healthy, term, singleton infants reporting values for the composition of breast milk during the first month of life were included. The energy content of colostrum (mean, SEM: 53.6 ± 2.5 kcal/100 mL), transitional milk (57.7 ± 4.2 kcal/100 mL), and mature milk (65.2 ± 1.1 kcal/100 mL) was lower than conventional infant formula (67 kcal/100 mL) on all days analyzed. The protein concentration of colostrum (2.5 ± 0.2 g/100 mL) and transitional milk (1.7 ± 0.1 g/100 mL) was higher than formula (1.4 g/100 mL), while the protein content of mature milk (1.3 ± 0.1 g/100 mL) was slightly lower. Formula-fed infants consume a higher volume and more energy dense milk in early life leading to faster growth which could potentially program a greater risk of long-term obesity
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