10,171 research outputs found
Estudo bibliométrico da produção cientÃfica em pinhão-manso, no Web of Science, no perÃodo de 1945 a 2011.
bitstream/item/54652/1/CITE-08.pd
Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes.
The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-nucleated F-actin 'shell' in starfish oocytes, in contrast to microtubule-driven tearing in mammalian fibroblasts. Here, we address the mechanism of F-actin-driven NE rupture by correlated live-cell, super-resolution and electron microscopy. We show that actin is nucleated within the lamina sprouting filopodia-like spikes towards the nuclear membranes. These F-actin spikes protrude pore-free nuclear membranes, whereas the adjoining membrane stretches accumulate NPCs associated with the still-intact lamina. Packed NPCs sort into a distinct membrane network, while breaks appear in ER-like, pore-free regions. Thereby, we reveal a new function for actin-mediated membrane shaping in nuclear rupture that is likely to have implications in other contexts such as nuclear rupture observed in cancer cells
Fractional Hamiltonian analysis of higher order derivatives systems
The fractional Hamiltonian analysis of 1+1 dimensional field theory is
investigated and the fractional Ostrogradski's formulation is obtained. The
fractional path integral of both simple harmonic oscillator with an
acceleration-squares part and a damped oscillator are analyzed. The classical
results are obtained when fractional derivatives are replaced with the integer
order derivatives.Comment: 13 page
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Calcinosis cutis: A rare feature of adult dermatomyositis
Abstract
Dermatomyositis is an idiopathic inflammatory myopathy with
characteristic cutaneous manifestations. We describe a case of a 55-
year-old woman with dermatomyositis who presented with dystrophic
calcinosis resistant to medical treatment
Lagrangian formulation of classical fields within Riemann-Liouville fractional derivatives
The classical fields with fractional derivatives are investigated by using
the fractional Lagrangian formulation.The fractional Euler-Lagrange equations
were obtained and two examples were studied.Comment: 9 page
Concepciones de profesores en formación respecto a la enseñanza del álgebra lineal
En los últimos años ha cobrado interés investigar diversos aspectos relacionados con la enseñanza del álgebra lineal en diferentes niveles educativos. Se han analizado desde la incorporación de nuevas tecnologÃas hasta el tipo de estrategias para una buena enseñanza de estos contenidos. Esta última lÃnea ha llevado a Harel (2000) a enunciar tres principios fundamentales para su enseñanza: el de concreción, el de necesidad y el de generalidad
The graphene sheet versus the 2DEG: a relativistic Fano spin-filter via STM and AFM tips
We explore theoretically the density of states (LDOS) probed by an STM tip of
2D systems hosting an adatom and a subsurface impurity,both capacitively
coupled to AFM tips and traversed by antiparallel magnetic fields. Two kinds of
setups are analyzed, a monolayer of graphene and a two-dimensional electron gas
(2DEG). The AFM tips set the impurity levels at the Fermi energy, where two
contrasting behaviors emerge: the Fano factor for the graphene diverges, while
in the 2DEG it approaches zero. As result, the spin-degeneracy of the LDOS is
lifted exclusively in the graphene system, in particular for the asymmetric
regime of Fano interference. The aftermath of this limit is a counterintuitive
phenomenon, which consists of a dominant Fano factor due to the subsurface
impurity even with a stronger STM-adatom coupling. Thus we find a full
polarized conductance, achievable just by displacing vertically the position of
the STM tip. To the best knowledge, our work is the first to propose the Fano
effect as the mechanism to filter spins in graphene. This feature arises from
the massless Dirac electrons within the band structure and allows us to employ
the graphene host as a relativistic Fano spin-filter
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