49 research outputs found

    Wellbeing and Society: Towards Quantification of the Co-benefits of Wellbeing

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    This is the final version. Available on open access from Springer Verlag via the DOI in this recordThe objectives of this paper are twofold. First, it reviews the empirical evidence showing the existence of linkage between wellbeing and possible co-benefits, investigating in particular the positive effect that happiness and life satisfaction can have on health, social outcomes, employment, education and environmental behaviours. Second, it presents the valuation methods that have been proposed in the literature to place a monetary value on these outcomes. With wellbeing having become more and more relevant for individuals and policy makers, the full understanding of the co-benefits of wellbeing is central for the design and development of wellbeing interventions. As a consequence, the evaluation of the co-benefits of wellbeing is of crucial importance for the appropriate allocation of resources towards such strategies.Innovate U

    From a micro-polymeric pipe to a mini-polymeric pulsating heat pipe

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    Paper presented at the 6th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, South Africa, 30 June - 2 July, 2008.In this work, a preliminary study related to the design and manufacturing of a micro polymeric pipe for micro heat exchangers was performed. Among possible polymeric materials, a thermoplastic copolyester elastomer composed of polybuthylene-terephthalate, as crystalline phase, and long glycol chains, as the amorphous one (Hytrel® 6356, Dupont) was selected, both unloaded and loaded with 7 % w/w carbon powder. A microextrusion process was set up to obtain microtubes and the thermo-mechanical characteristics of the produced pipes were studied. Thermal properties of extruded Hytrel® remained almost the same, in terms of melting temperature (Tm ≅ 208 °C) and enthalpy change of fusion (ΔH ≅ 45 mJ/mg), although the material was C-loaded. The thermomechanical tests performed on unloaded and C-loaded Hytrel® microtubes at 25 and 70 °C (possible working temperature) detected a considerable increase in the mechanical properties of C-loaded Hytrel®, compared to the unloaded one. In particular, a relevant improvement of the elastic modulus at 70 °C for the C-loaded microtubes was observed, demonstrating a better thermal stability at high temperature. Moreover, the fabrication of a micro heat exchanger prototype and prteliminary tests with different cooling fluids confirmed the possibility of using Hytrel® for electronic applications, as a good thermal exchange was evidenced.vk201

    EXACT2: the semantics of biomedical protocols

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    © 2014 Soldatova et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.This article has been made available through the Brunel Open Access Publishing Fund.Background: The reliability and reproducibility of experimental procedures is a cornerstone of scientific practice. There is a pressing technological need for the better representation of biomedical protocols to enable other agents (human or machine) to better reproduce results. A framework that ensures that all information required for the replication of experimental protocols is essential to achieve reproducibility. Methods: We have developed the ontology EXACT2 (EXperimental ACTions) that is designed to capture the full semantics of biomedical protocols required for their reproducibility. To construct EXACT2 we manually inspected hundreds of published and commercial biomedical protocols from several areas of biomedicine. After establishing a clear pattern for extracting the required information we utilized text-mining tools to translate the protocols into a machine amenable format. We have verified the utility of EXACT2 through the successful processing of previously ‘unseen’ (not used for the construction of EXACT2) protocols. Results: The paper reports on a fundamentally new version EXACT2 that supports the semantically-defined representation of biomedical protocols. The ability of EXACT2 to capture the semantics of biomedical procedures was verified through a text mining use case. In this EXACT2 is used as a reference model for text mining tools to identify terms pertinent to experimental actions, and their properties, in biomedical protocols expressed in natural language. An EXACT2-based framework for the translation of biomedical protocols to a machine amenable format is proposed. Conclusions: The EXACT2 ontology is sufficient to record, in a machine processable form, the essential information about biomedical protocols. EXACT2 defines explicit semantics of experimental actions, and can be used by various computer applications. It can serve as a reference model for for the translation of biomedical protocols in natural language into a semantically-defined format.This work has been partially funded by the Brunel University BRIEF award and a grant from Occams Resources
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