Extended book review: Transnational trade unionism: dream and reality

Book review of : Reiner Tosstorff, The Red International of Labour Unions (RILU), 1920–1937, Leiden: Brill, 2016; 918 pp.: ISBN 9789004236646, (hbk); Chicago, IL: Haymarket Books, 2018; 918 pp.: ISBN 9781608468164, (pbk

Left out of Europe?

SIGLEGBUnited Kingdo

Global business Global rights

SIGLEAvailable from British Library Document Supply Centre-DSC:3863.107(575) / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Making flexibility work

Part of the 'Economic Futures' programmeAvailable from British Library Document Supply Centre-DSC:3863.107(595) / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

MAGD Trial-Memantine for Agitation in Alzheimer’s Dementia

OBJECTIVE: Does memantine improve agitation in dementia DESIGN: Double blind randomized placebo controlled trial SETTING: Nursing Homes PARTICIPANTS: 153 patients with Alzheimer’s dementia INTERVENTION: Memantine vs placebo MEASUREMENTS: Cohen Mansfield Agitation Inventory (CMAI), Neuro-Psychiatric Inventory (NPI), Severe Impairment Battery (SIB), Quality of Life-AD (QOL-AD) RESULTS:CMAI-there was no statistically significant difference for mean change- memantine vs placebo p=0.17. NPI-9 point difference between memantine vs placebo p=0.01 Hallucinations, aberrant motor behaviour and sleep-p=0.03 Agitation, disinhibition and irritability-p=0.001 SIB-Memantine compared to placebo had a strong augmentation of the percent change from baseline to week 12 p=0.02 QOL-AD-Memantine group are significantly more satisfied about the contact with friends compared to the patients treated with placebo p=0.04. CONCLUSION: In this study of agitated AD patients benefit was not shown for agitation on the CMAI with memantine but the NPI reached signficance and the agitation, disinhibiton and irritability cluster improvement was significant. Cognition and quality of life improved. We believe that this study supports the use of Memantine in agitated patients with Alzheimer’s dementi