482 research outputs found

    An Introduction to the RESearch Queueing Package for Modeling Computer Systems and Communication Networks

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    A queueing network is an important tool for modeling systems where performance is principally affected by contention for resources. Such systems include computer systems, communication networks and manufacturing lines. In order to effectively use queuing networks as performance models, appropriate software is necessary for definition ofthe networks to be solved, for solution ofthe networks and for examination of the performance measures obtained. The RESearch Queueing Package (RESQ) and the RESearch Queueing Package Modeling Environment (RESQME) form a system for constructing, solving and analyzing extended queueing network models. We refer to the class of RESQ networks as extended because of characteristics which allow effective representation of system detail. RESQ incorporates a high level language to concisely describe the structure of the model and to specify constraints on the solution. A main feature of the language is the capability to describe models in a hierarchical fashion, allowing an analyst to define submodels to be used analogously to use of macros in programming languages. RESQ also provides a variety of methods for estimating the accuracy of simulation results and for determining simulation run lengths. RESQME is a graphical interface for RESQ. In this introduction, we limit our examples to computer systems and communication networks. Acknowledgement: The authors wish to thank their co-developers of RESQME: Jim Kurose and Kurt Gordon. We also want to thank Ben Antanaitis, Howard Jachter, Jack Servier, Daniel Souday and Peter Welch for their many suggestions which helped improve the RESQME package and Anil Aggarwal, Al Blum, Gary Burkland, Rocky Chang, Janet Chen, Diana Coles, Prakash Deka, Paul Lnewner, and Geoff Parker for their work in implementing RESQME. We would also like to thank our users for their ideas and feedback that we tried to incorporate in RESQ and RESQME. We remain indebted to Charlie Sauer for his design, guidance, inspiration, and development ofthe RESQ languag

    The Altitude Effect on Air Speed Indicators II

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    In an investigation described in NACA Technical Report 110, it was shown that under certain conditions, particularly for the relatively low-speed flight of airships, the data obtained were not sufficiently accurate. This report describes an investigation in which the data obtained were sufficiently accurate and complete to enable the viscosity correction to be deduced quantitatively for a number of the air-speed pressure nozzles in common use. The report opens with a discussion of the theory of the performance of air-speed nozzles and of the calibration of the indicators, from which the theory of the altitude correction is developed. Then follows the determination of the performance characteristics of the nozzles and calibration constants used for the indicators. In the latter half of the report, the viscosity correction is computed for the Zahm Pitot-venturi nozzles

    Neurasthenia, with Notes and Comments on Twenty Cases Observed in General Practice

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    The role of aspirin in the prevention of ovarian, endometrial and cervical cancers

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    Drug repurposing is the application of an existing licenced drug for a new indication and potentially provides a faster and cheaper approach to developing new anti-cancer agents. Gynaecological cancers contribute significantly to the global cancer burden, highlighting the need for low cost, widely accessible therapies. A large body of evidence supports the role of aspirin as an anti-cancer agent, and a number of randomized trials are currently underway aiming to assess the potential benefit of aspirin in the treatment of cancer. This review summarizes the evidence underpinning aspirin use for the prevention of the development and recurrence of gynaecological cancers (ovarian, endometrial and cervical) and potential mechanisms of action

    Do rewardless orchids show a positive relationship between phenotypic diversity and reproductive success?

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    Among rewardless orchids, pollinator sampling behavior has been suggested to drive a positive relationship between population phenotypic variability and absolute reproductive success, and hence population fitness. We tested this hypothesis by constructing experimental arrays using the rewardless orchid Dactylorhiza sambucina, which is dimorphic for corolla color. We found no evidence that polymorphic arrays had higher mean reproductive success than monomorphic arrays for pollinia removal, pollen deposition, or fruit set. For pollinia removal, monomorphic yellow arrays had significantly greater reproductive success, and monomorphic red the least. A tendency for yellow arrays to have higher pollen deposition was also found. We argue that differential population fitness was most likely to reflect differential numbers of pollinators attracted to arrays, through preferential long-distance attraction to arrays with yellow inflorescences. Correlative studies of absolute reproductive success in 52 populations of D. sambucina supported our experimental results. To our knowledge this is the first study to suggest that attraction of a greater number of pollinators to rewardless orchids may be of greater functional importance to population fitness, and thus ecology and conservation, than are the behavioral sequences of individual pollinators

    Rule-Based Run Control and Evaluation for Simulation

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    RC 19494 (84719) Modeling projects are often faced with a large parameter space that has to be explored in order to produce a set of performance measures representing the behavior of the systems under study. In this paper, we describe a software component that provides the analyst with the functionality to specify a design of experiments and execute a search algorithm over the resulting parameter space. The component invokes the associated simulation runs and compares the results to a goal to determine the solution. This component has been implemented as the run control mechanism in the RESearch Queueing Modeling Environment (RESQME). We demonstrate the use of this experimental run control and evaluation component for simple enumeration of the parameter space, interactive evaluation, as well as generalized rule-based control

    Seal Occurrence and Habitat Use during Summer in Petermann Fjord, Northwestern Greenland

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    Ice-associated seals are considered especially susceptible and are potentially the first to modify distribution and habitat use in response to physical changes associated with the changing climate. Petermann Glacier, part of a unique ice-tongue fjord environment in a rarely studied region of northwestern Greenland, lost substantial sections of its ice tongue during major 2010 and 2012 calving events. As a result, changes in seal habitat may have occurred. Seal occurrence and distribution data were collected in Petermann Fjord and adjacent Nares Strait region over 27 days (2 to 28 August) during the multidisciplinary scientific Petermann 2015 Expedition on the icebreaker Oden. During 239.4 hours of dedicated observation effort, a total of 312 individuals were recorded, representing four species: bearded seal (Erignathus barbatus), hooded seal (Crystophora cristata), harp seal (Pagophilus groenlandicus), and ringed seal (Pusa hispida). Ringed seals were recorded significantly more than the other species (χ2 = 347.4, df = 3, p < 0.001, n = 307). We found significant differences between species in haul-out (resting on ice) behavior (χ2 = 133.1, df = 3, p < 0.001, n = 307). Bearded seals were more frequently hauled out (73.1% n = 49), whereas ringed seals were almost exclusively in water (93.9%, n = 200). Differences in average depth and ice coverage where species occurred were also significant: harp seals and bearded seals were found in deeper water and areas of greater ice coverage (harp seals: 663 ± 366 m and 65 ± 14% ice cover; bearded seals: 598 ± 259 m and 50 ± 21% ice cover), while hooded seals and ringed seals were found in shallower water with lower ice coverage (hooded seals: 490 ± 163 m and 38 ± 19% ice cover; ringed seals: 496 ± 235 m, and 21 ± 20% ice cover). Our study provides an initial look at how High Arctic seals use the rapidly changing Petermann Fjord and how physical variables influence their distribution in one of the few remaining ice-tongue fjord environments.Les phoques associĂ©s aux glaces sont considĂ©rĂ©s comme trĂšs susceptibles et sont potentiellement les premiers Ă  modifier la rĂ©partition de leur population et la façon dont ils utilisent leur habitat en rĂ©ponse aux changements physiques dĂ©coulant des changements climatiques. Le glacier Petermann fait partie d’une langue glaciaire de fjord unique dans une rĂ©gion rarement Ă©tudiĂ©e du nord-ouest du Groenland. De gros blocs de glace se sont dĂ©tachĂ©s du glacier Petermann pendant le vĂȘlage de 2010 Ă  2012. Par consĂ©quent, l’habitat des phoques aurait pu ĂȘtre modifiĂ©. Pendant 27 jours (du 2 au 28 aoĂ»t), des donnĂ©es sur la prĂ©sence et la rĂ©partition des phoques ont Ă©tĂ© recueillies au fjord Petermann et dans la rĂ©gion adjacente du dĂ©troit de Nares dans le cadre de l’expĂ©dition scientifique multidisciplinaire Petermann 2015 sur le brise-glace Oden. Au cours de 239,4 heures d’observation soutenue, la prĂ©sence d’un total de 312 phoques reprĂ©sentant quatre espĂšces a Ă©tĂ© notĂ©e : le phoque barbu (Erignathus barbatus), le phoque Ă  capuchon (Crystophora cristata), le phoque du Groenland (Pagophilus groenlandicus) et le phoque annelĂ© (Pusa hispida). La prĂ©sence de phoques annelĂ©s est considĂ©rablement plus importante que celle des autres espĂšces (χ2 = 347,4, ddl = 3, p < 0,001, n = 307). Nous avons constatĂ© une diffĂ©rence significative dans les comportements d’échouerie (repos sur la glace) des phoques selon les espĂšces (χ2 = 133,11, ddl = 3, p < 0,001, n = 307). Les phoques barbus Ă©taient plus souvent hors de l’eau (73,1 %, n = 49), tandis que les phoques annelĂ©s se trouvaient presque exclusivement dans l’eau (93,9 %, n = 200). Des diffĂ©rences significatives en ce qui a trait Ă  la prĂ©sence des espĂšces selon la profondeur et la couverture glaciaire ont Ă©tĂ© notĂ©es. Les phoques du Groenland et les phoques barbus frĂ©quentent les profondeurs d’eau moyennes (663 ± 366 m et 598 ± 259 m, respectivement) et les rĂ©gions oĂč la couverture de glace correspond Ă  la moyenne supĂ©rieure (65 ± 14 % et 50 ± 21 %, respectivement), tandis que les phoques Ă  capuchon et les phoques annelĂ©s frĂ©quentent les eaux moins profondes (490 ± 163 m et 496 ± 235 m, respectivement) et les rĂ©gions oĂč la couverture de glace correspond Ă  la moyenne infĂ©rieure (38 ± 19 % et 21 ± 20, respectivement). Notre Ă©tude prĂ©sente un premier aperçu de la façon dont les phoques de l’ExtrĂȘme-Arctique utilisent le fjord Petermann en Ă©volution rapide et de l’influence des variables physiques sur leur rĂ©partition dans l’une des rares langues glaciaires de fjord restantes

    RESQME and Stand-Alone Simulation on a Workstation

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    RC 16037 (#71232) The Research Queueing Package Modeling Environment (RESQME) provides a graphical environment for constructing and solving extended queueing network models ofmanufacturing systems, for plotting graphs of results and for viewdng animations of models. The modeling environment can be run entirely on a workstation or optionally can execute large simulations on a host system using cooperative processing. In this paper we give a brief introduction to RESQME and to the RESQ modeling elements. We demonstrate how to use the package by constructing a simple model of part of a manufacturing line and solve this model to produce charts of performance measures and an animation which shows how the jobs flow through the system. By having the simulation available for use on the workstation and cooperatively on the host, RESQME provides a unique tool for understanding the performance of manufacturing systems. A user can do most of the model debugging locally on the workstation and make short pĂŒot runs to get a feeling for the amount of resources necessary to make more realistic experiments on the ‱ host. Then long runs which investigate large parts ofthe parameter space can be done cooperatively on the host. Whether the model is solved on the workstation or on the hosMhe graphics environment provides the same user interface to all of the underlying files. The processor where the model is solved is transparent to the user. In aU cases, the user has easy access to plots ofresults and to the animation ofthe model diagra
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