9,928 research outputs found
Macrofossil extinction patterns at Bay of Biscay Cretaceous-Tertiary boundary sections
Researchers examined several K-T boundary cores at Deep Sea Drilling Project (DSDP) core repositories to document biostratigraphic ranges of inoceramid shell fragments and prisms. As in land-based sections, prisms in the deep sea cores disappear well before the K-T boundary. Ammonites show a very different extinction pattern than do the inoceramids. A minimum of seven ammonite species have been collected from the last meter of Cretaceous strata in the Bay of Biscay basin. In three of the sections there is no marked drop in either species numbers or abundance prior to the K-T boundary Cretaceous strata; at the Zumaya section, however, both species richness and abundance drop in the last 20 m of the Cretaceous, with only a single ammonite specimen recovered to date from the uppermost 12 m of Cretaceous strata in this section. Researchers conclude that inoceramid bivalves and ammonites showed two different times and patterns of extinction, at least in the Bay of Biscay region. The inoceramids disappeared gradually during the Early Maestrichtian, and survived only into the earliest Late Maestrichtian. Ammonites, on the other hand, maintained relatively high species richness throughout the Maestrichtian, and then disappeared suddenly, either coincident with, or immediately before the microfossil extinction event marking the very end of the Cretaceous
Two \u3ci\u3eEntomophthora\u3c/i\u3e Species Associated with Disease Epizootics of the Alfalfa Weevil, \u3ci\u3eHypera Postica\u3c/i\u3e (Coleoptera: Curculionidae), in Ontario
Recent studies have shown that disease epizootics in Ontario populations of the alfalfa weevil, Hypera postica (Gyllenhal), are caused by a complex of two fungi
Medium-term prognosis of an incident cohort of parkinsonian patients compared to controls
Funding This work was supported by Parkinson's UK (grant numbers G0502, G0914), BMA Doris Hillier Award, the BUPA Foundation, NHS Grampian Endowments, RS MacDonald Trust.Peer reviewedPublisher PD
A fully-coherent all-sky search for gravitational-waves from compact binary coalescences
We introduce a fully-coherent method for searching for gravitational wave
signals generated by the merger of black hole and/or neutron star binaries.
This extends the coherent analysis previously developed and used for targeted
gravitational wave searches to an all-sky, all-time search. We apply the search
to one month of data taken during the fifth science run of the LIGO detectors.
We demonstrate an increase in sensitivity of 25% over the coincidence search,
which is commensurate with expectations. Finally, we discuss prospects for
implementing and running a coherent search for gravitational wave signals from
binary coalescence in the advanced gravitational wave detector data.Comment: 17 pages, 12 figure
Co-morbidity burden in Parkinsonās disease : Comparison with controls and its influence on prognosis
Financial support This study was funded by Parkinsonās UK, the Scottish Chief Scientist Office, NHS Grampian endowments, the BMA Doris Hillier award, RS Macdonald Trust, the BUPA Foundation, and SPRING. The funders had no involvement in the study. Acknowledgements We acknowledge funding for the PINE study from Parkinsonās UK (G-0502, G-0914, G-1302), the Scottish Chief Scientist Office(CAF/12/05), the BMA Doris Hillier award, RS Macdonald Trust, the BUPA Foundation, NHS Grampian endowments and SPRING. We thank the patients and controls for their participation and the research staff who collected data and supported the study database.Peer reviewedPostprintPostprintPublisher PD
The impact of consent on observational research: a comparison of outcomes from consenters and non consenters to an observational study
Background
Public health benefits from research often rely on the use of data from personal medical records. When neither patient consent nor anonymisation is possible, the case for accessing such records for research purposes depends on an assessment of the probabilities of public benefit and individual harm.
Methods
In the late 1990s, we carried out an observational study which compared the care given to affluent and deprived women with breast cancer. Patient consent was not required at that time for review of medical records, but was obtained later in the process prior to participation in the questionnaire study. We have re-analysed our original results to compare the whole sample with those who later provided consent.
Results
Two important findings emerged from the re-analysis of our data which if presented initially would have resulted in insufficient and inaccurate reporting. Firstly, the reduced dataset contains no information about women presenting with locally advanced or metastatic cancer and we would have been unable to demonstrate one of our initial key findings: namely a larger number of such women in the deprived group. Secondly, our re-analysis of the consented women shows that significantly more women from deprived areas (51 v 31%, p = 0.018) received radiotherapy compared to women from more affluent areas. Previously published data from the entire sample demonstrated no difference in radiotherapy treatment between the affluent and deprived groups.
Conclusion
The risk benefit assessment made regarding the use of medical records without consent should include the benefits of obtaining research evidence based on 100% of the population and the possibility of inappropriate or insufficient findings if research is confined to consented populations
Scottish theme towns: have new identities enhanced development?
Three small towns in southwest Scotland have recently been branded as distinct theme towns, based on books, artists and food. This is an attempt to make them more attractive to visitors and thereby improve their economy. The objective of this research is to establish whether the new identities possessed by the towns have enhanced their development. It is argued, using data reviewing the past decade, that they have all developed, albeit at different rates, in terms of the economy and culture. Moreover, it is maintained that social capital has been enhanced and is a factor whose importance has been under-appreciated by planners and observers of this type of process. The relevance of the new identity to the pre-branding identity is also seen as a factor in successful development and ideas of authenticity and heritage are brought to bear on the relationship
Comparison of predictive scores of symptomatic intracerebral haemorrhage after stroke thrombolysis in a single centre
Peer reviewedPublisher PD
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