195 research outputs found
Thermal conductivity in the vicinity of the quantum critical endpoint in Sr3Ru2O7
Thermal conductivity of Sr3Ru2O7 was measured down to 40 mK and at magnetic
fields through the quantum critical endpoint at H_c = 7.85 T. A peak in the
electrical resistivity as a function of field was mimicked by the thermal
resistivity. In the limit as T -> 0 K we find that the Wiedemann-Franz law is
satisfied to within 5% at all fields, implying that there is no breakdown of
the electron despite the destruction of the Fermi liquid state at quantum
criticality. A significant change in disorder (from (H=0T) = 2.1
cm to 0.5 cm) does not influence our conclusions. At
finite temperatures, the temperature dependence of the Lorenz number is
consistent with ferromagnetic fluctuations causing the non-Fermi liquid
behavior as one would expect at a metamagnetic quantum critical endpoint.Comment: 4 figures, published in PR
Heat Transport in a Strongly Overdoped Cuprate: Fermi Liquid and Pure d-wave BCS Superconductor
The transport of heat and charge in the overdoped cuprate superconductor
Tl_2Ba_2CuO_(6+delta) was measured down to low temperature. In the normal
state, obtained by applying a magnetic field greater than the upper critical
field, the Wiedemann-Franz law is verified to hold perfectly. In the
superconducting state, a large residual linear term is observed in the thermal
conductivity, in quantitative agreement with BCS theory for a d-wave
superconductor. This is compelling evidence that the electrons in overdoped
cuprates form a Fermi liquid, with no indication of spin-charge separation.Comment: 4 pages, 2 figures, published version, title changed, Phys. Rev.
Lett. 89, 147003 (2002
Association between chiropractic care and use of prescription opioids among older medicare beneficiaries with spinal pain: a retrospective observational study
Background: The burden of spinal pain can be aggravated by the hazards of opioid analgesics, which are still widely prescribed for spinal pain despite evidence-based clinical guidelines that identify non-pharmacological therapies as the preferred first-line approach. Previous studies have found that chiropractic care is associated with decreased use of opioids, but have not focused on older Medicare beneficiaries, a vulnerable population with high rates of co-morbidity and polypharmacy. The purpose of this investigation was to evaluate the association between chiropractic utilization and use of prescription opioids among older adults with spinal pain. Methods: We conducted a retrospective observational study in which we examined a nationally representative multi-year sample of Medicare claims data, 2012–2016. The study sample included 55,949 Medicare beneficiaries diagnosed with spinal pain, of whom 9,356 were recipients of chiropractic care and 46,593 were non-recipients. We measured the adjusted risk of filling a prescription for an opioid analgesic for up to 365 days following diagnosis of spinal pain. Using Cox proportional hazards modeling and inverse weighted propensity scoring to account for selection bias, we compared recipients of both primary care and chiropractic to recipients of primary care alone regarding the risk of filling a prescription. Results: The adjusted risk of filling an opioid prescription within 365 days of initial visit was 56% lower among recipients of chiropractic care as compared to non-recipients (hazard ratio 0.44; 95% confidence interval 0.40–0.49). Conclusions: Among older Medicare beneficiaries with spinal pain, use of chiropractic care is associated with significantly lower risk of filling an opioid prescription
Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis
The finding of TDP-43 as a major component of ubiquitinated protein inclusions in amyotrophic lateral sclerosis (ALS) has led to the identification of 30 mutations in the transactive response-DNA binding protein (TARDBP) gene, encoding TDP-43. All but one are in exon 6, which encodes the glycine-rich domain. The aim of this study was to determine the frequency of TARDBP mutations in a large cohort of motor neurone disease patients from Northern England (42 non-superoxide dismutase 1 (SOD1) familial ALS (FALS), nine ALS-frontotemporal dementia, 474 sporadic ALS (SALS), 45 progressive muscular atrophy cases). We identified four mutations, two of which were novel, in two familial (FALS) and two sporadic (SALS) cases, giving a frequency of TARDBP mutations in non-SOD1 FALS of 5% and SALS of 0.4%. Analysis of clinical data identified that patients had typical ALS, with limb or bulbar onset, and showed considerable variation in age of onset and rapidity of disease course. However, all cases had an absence of clinically overt cognitive dysfunction
Breakdown of Fermi-liquid theory in a cuprate superconductor
The behaviour of electrons in solids is remarkably well described by Landau's
Fermi-liquid theory, which says that even though electrons in a metal interact
they can still be treated as well-defined fermions, called ``quasiparticles''.
At low temperature, the ability of quasiparticles to transport heat is strictly
given by their ability to transport charge, via a universal relation known as
the Wiedemann-Franz law, which no material in nature has been known to violate.
High-temperature superconductors have long been thought to fall outside the
realm of Fermi-liquid theory, as suggested by several anomalous properties, but
this has yet to be shown conclusively. Here we report on the first experimental
test of the Wiedemann-Franz law in a cuprate superconductor,
(Pr,Ce)CuO. Our study reveals a clear departure from the universal law
and provides compelling evidence for the breakdown of Fermi-liquid theory in
high-temperature superconductors.Comment: 7 pages, 3 figure
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