Impact of sexual trajectories of men who have sex with men on the reduction in HIV transmission by pre-exposure prophylaxis

Acknowledgments This project was funded by the Netherlands Organisation for Health Research and Development ZonMw grant 522002004.Peer reviewedPublisher PD

Preterm birth and adult wealth: mathematics skills count

Each year, 15 million babies are born preterm worldwide. Preterm birth is associated with adverse neurodevelopmental outcomes across the lifespan. Recent registry-based studies suggest that preterm birth is associated with lower wealth in adulthood, but the mediating mechanisms are unknown. This study investigated whether the relationship between preterm birth and low adult wealth is mediated by poor academic abilities and educational qualifications. Participants were members of two British population-based birth cohorts born in 1958 and 1970. Results showed that preterm birth was associated with decreased wealth at 42 years of age. This association was mediated by poorer intelligence, reading and, in particular, mathematics attainment in middle childhood, and lower educational qualifications in young adulthood. Findings were similar in both cohorts, suggesting that these mechanisms may be time invariant. Special educational support in childhood may prevent preterm children from becoming less wealthy as adults

The Rhythm of Risk : Sexual Behaviour, PrEP Use and HIV Risk Perception Between 1999 and 2018 Among Men Who Have Sex with Men in Amsterdam, The Netherlands

Funding Information: This project was funded by the Netherlands Organisation for Health Research and Development ZonMw Grant 522004009. The Amsterdam Cohort Studies on HIV infection, a collaboration between the Public Health Service of Amsterdam, the Amsterdam University Medical Centers location AMC, Sanquin Blood Supply Foundation, MC Jan van Goyen and DC Clinics Lairesse, are part of the Netherlands HIV Monitoring Foundation and financially supported by the Netherlands National Institute for Public Health and the Environment. The ACS gratefully acknowledge all the study participants for their co-operation and participation and research nurses for collecting the data (Samantha de Graaf and Leeann Storey). The authors also thank Dominique Loomans, Ertan Ersan, Maartje Dijkstra, Liza Coyer, and Ward van Bilsen for data management.Peer reviewedPublisher PD

Time for change : Transitions between HIV risk levels and determinants of behavior change in men who have sex with men

Funding Information: This project was funded by the Netherlands Organisation for Health Research and Development ZonMw grant 522004009. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

Generación automática de reglas de categorización de texto en un método híbrido basado en aprendizaje

En este artículo se evalúan diferentes técnicas para la generación automática de reglas que se emplean en un método híbrido de categorización automática de texto. Este método combina un algoritmo de aprendizaje computacional con diferentes sistemas basados en reglas en cascada empleados para el filtrado y reordenación de los resultados proporcionados por dicho modelo base. Aquí se describe una implementación realizada mediante el algoritmo kNN y un lenguaje básico de reglas basado en listas de términos que aparecen en el texto a clasificar. Para la evaluación se utiliza el corpus de noticias Reuters-21578. Los resultados demuestran que los métodos de generación de reglas propuestos producen resultados muy próximos a los obtenidos con la aplicación de reglas generadas manualmente y que el sistema híbrido propuesto obtiene una precisión y cobertura comparables a la de los mejores métodos del estado del arte

Применение методов управления себестоимостью продукции

Целью данной работы является исследование новых методов управления себестоимостью продукции на предприятии

The Stability of Problem Behavior Across the Preschool Years: An Empirical Approach in the General Population

This study examined the stability of internalizing and externalizing problems from age 1.5 to 6 years, while taking into account developmental changes in the presentation of problems. The study comprised a population-based cohort of 7,206 children (50.4 % boys). At ages 1.5, 3, and 6 years, mothers reported on problem behavior using the Child Behavior Checklist/1.5-5 (CBCL/1.5-5). At each age we performed latent profile analysis on the CBCL/1.5-5 scales. Latent transition analysis (LTA) was applied to study the stability of problem behavior. Profiles of problem behavior varied across ages. At each age, 82–87 % of the children did not have problems whereas approximately 2 % showed a profile of co-occurring internalizing and externalizing problems. This profile was more severe (with higher scores) at 6 years than at earlier ages. A predominantly internalizing profile only emerged at 6 years, while a profile with externalizing problems and emotional reactivity was present at each age. LTA showed that, based on profiles at 1.5 and 3 years, it was difficult to predict the type of profile at 6 years. Children with a profile of co-occurring internalizing and externalizing problems early in life were most likely to show problem behavior at 6 years. This study shows that the presentation of problem behavior changes across the preschool period and that heterotypic continuity of problems is very common among preschoolers. Children with co-occurring internalizing and externalizing problems were most likely to show persisting problems. The use of evidence-based treatment for these young children may prevent psychiatric problems across the life course

Cognitive functioning in children with internalising, externalising and dysregulation problems: a population-based study

Psychiatric symptoms in childhood are closely related to neurocognitive deficits. However, it is unclear whether