Upaya Peningkatan Kualitas Pelayanan Publik di Era Otonomi Daerah

The quality of public services and many more now is still out of order especially in public autonomy. In fact, it needs more conduct by the author (government) through finding more solutions such as revitalization, restructure, deregulation and increasing the ability of officer professionalism and people participate to do, includes honor, and giving sanction, toward public services unit. This effort can be realized when every unit work together, as the impact of the improving quality public services

Teori ACTORS dalam Pemberdayaan Masyarakat

By using the concept of empowerment that are offered within the framework of the theory of "ACTORS", then the changes that will result is a change has been planned, because the input to be used in the change was anticipated early on so that the output will be produced capable of optimally efficient. The study of the management of community development using the framework of "ACTORS" will be able to raise awareness, authority, confidence and competence, trust, oppurtinities, responsibilities, support, initiative, and creativity to change the situation towards the power in which communities have self-respect, self confident, and self relience, so they have the knowledge and understanding for self-empowerment on an ongoing basis

Etika Pelayanan Publik

Understanding of ethics in public management is an important and strategic basic competence that has to be owned and practiced by public bureucrat consistantly in the implementation of government, development, and public service for society. Therefore a study of understanding and implementation of the concept of ethics in public service need to be socialized, especially that of related to equality, equity, loyalty, and responsibility. This article will discuss about how important the understanding and implementation of ethics in public service

Systems thinkers think About systems education under the April 2010 (volcanic ash) clouds of Austria

The fragmented nature of systems education with multiple traditions expressed in very different ways at different institutions with ultimate confusing effects on the community of learners (students, managers, policy makers, etc), led to a group of Systems Thinkers to discuss and create generic curricula for education and learning about systems for the generalist and specialist tracks. An active network of systems educators and stakeholders who can benefit from enhanced systems education in having to deal with complex issues, was also explored. In this presentation some guidelines for designing introductory and advanced courses will be discussed. The Introduction to Systemic Thinking and Practice course is intended as an introductory course for students from all disciplines. The Advanced Systemic Thinking and Practice course is intended as a more advanced course for students who are faced with complex issues that require a trans-disciplinary and integrated approach. The designs contain a set of key systems concepts and frameworks relevant to the appropriate level, along with some indicative tools and methods which will enable students to explore the concepts. The value of a Global Network of Systems Educators will also be discussed and how this network could help to fulfil the needs of managers, policy makers and society in general. An example will be given of how the integration of this network with the UQ-UNESCO/MAB Global Learning Laboratories NET could lead to more people (decision-and policy makers in Governments, managers, businesses, etc.) having the ability to practice systems thinking – all of these contributing to Systems Thinking becoming a more mainstream part of a sustainable society

Immunological aspects of the tumor microenvironment and epithelial-mesenchymal transition in gastric carcinogenesis

Infection with Helicobacter pylori, a Gram-negative, microaerophilic pathogen often results in gastric cancer in a subset of affected individuals. This explains why H. pylori is the only bacterium classified as a class I carcinogen by the World Health Organization. Several studies have pinpointed mechanisms by which H. pylori alters signaling pathways in the host cell to cause diseases. In this article, the authors have reviewed 234 studies conducted over a span of 18 years (2002–2020). The studies investigated the various mechanisms associated with gastric cancer induction. For the past 1.5 years, researchers have discovered new mechanisms contributing to gastric cancer linked to H. pylori etiology. Alongside alteration of the host signaling pathways using oncogenic CagA pathways, H. pylori induce DNA damage in the host and alter the methylation of DNA as a means of perturbing downstream signaling. Also, with H. pylori, several pathways in the host cell are activated, resulting in epithelial-to-mesenchymal transition (EMT), together with the induction of cell proliferation and survival. Studies have shown that H. pylori enhances gastric carcinogenesis via a multifactorial approach. What is intriguing is that most of the targeted mechanisms and pathways appear common with various forms of cancer