6,434 research outputs found

    Selection of Wiring Environment and Failure Rate Comparison Analysis in Aircraft Wiring Risk Assessment

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    AbstractThere has been a greater understanding of the importance of EWIS in aircraft safety in recent years. The expert opinion, a formal pair comparison experiment is applied to acquire wiring failure rate data. The selection of wiring environment and failure rate comparison is critical in doing the pair comparison experiment. Combined with a certain aircraft model, this paper studies the principles to choose wiring environment and the methods of failure rate comparison for aircraft risk assessment

    Near-field beamforming performance analysis for acoustic emission source localization

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    This paper attempts to study the localization performance of a near-field acoustic emission (AE) beamforming by varying parameters such as array types, localization velocity, the maximum diameter of the array and the sensor spacing. To investigate how those parameters affect localization performance, an improved finite element method is established to obtain AE signals which take real propagation characteristics and have high signal to noise ratio. And AE signals of the finite element simulation under different parameters are obtained based on the presented method. Then AE beamforming is used to localize AE sources, and the influences of these parameters on the AE beamforming localization performing are analyzed. The results indicate that the parameters have impact on the localization accuracy clearly. This work can provide a reference for the selection of parameters when the beamforming is used to localize AE sources

    Poly[[[diaqua­sodium]-μ3-5-carb­oxy-2-ethyl-1H-imidazole-4-carboxyl­ato-κ4 N 3,O 4:O 5:O 5] monohydrate]

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    In the title complex, {[Na(C7H7N2O4)(H2O)2]·H2O}n, the NaI atom exhibits a distorted octa­hedral geometry and is six-coordinated in an NO5 environment. The equatorial plane is defined by three O atoms and one N atom from two distinct 5-carb­oxy-2-ethyl-1H-imidazole-4-carboxyl­ate (H2EIDC) ligands and one coordinated water mol­ecule, and the apical sites are occupied by one carboxyl O atom from one H2EIDC ligand and one O atom from the other coordinated water mol­ecule. The NaI atoms are linked by H2EIDC ligands, generating an infinite double chain along the a axis. These chains are further connected via O—H⋯O and N—H⋯O hydrogen bonds into a three-dimensional supra­molecular network

    Current perspectives on genotype classification and individualized drug targeting in triple-negative breast cancer

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    Triple negative breast cancer (TNBC), a special subset of breast cancer, refers to negative expressions of estrogen receptors (ER), progesterone receptors (PR) and human epidermal growth receptor 2 (HER2). It is associated with extreme local recurrence and distant metastasis with highly invasive character. With advances in genomics, the bases of molecular classification of TNBC now include the heterogeneity of its expression at the molecular level and clinical pathology, apart from classical immunohistochemistry. Every subtype of TNBC has different individualized target drugs, which include epidermal growth factor receptor (EGFR) inhibitor, poly-AD-ribose polymerase (PARP) inhibitor, anthracycline or paclitaxel, immunotherapy and vascular endothelial growth factor receptor (VEGFR) inhibitor. Combinations of target drugs are also used. Thus, there are no widely recognized standards of genotype classification and individualized drug targeting in TNBC. In this review, relevant studies and latest developments on TNBC are presented.Keywords: Triple-negative breast cancer, Genotype classification, Individualized drug targeting, Breast cance

    Phase evolution of Ce-based heavy-fermion superconductors under pressure: a combined DFT+DMFT and effective-model description

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    In typical Ce-based heavy-fermion superconductors, superconducting (SC) phases emerge or can be tuned in proximity to the antiferromagnetic (AF) quantum critical point (QCP), but so far the explicit phase-evolution process and the coexistence of superconductivity and AF order near the QCP remain lack of understanding. Here, by combing DFT+DMFT with effective-model calculations, we provide a theoretical description for Ce-based SC compounds under pressure. Firstly, DFT+DMFT calculations for the normal states reveal that the Kondo hybridizations are significantly enhanced, while the initially localized ff electrons eventually become fully itinerant via a localized-itinerant crossover. In this context, we construct an effective model with tunable parameters under pressure, and show that the interplay of magnetic correlation and Kondo hybridization can drive successive transitions, from AF phase to AF+SC coexisting phase, then to paramagnetic SC phase via an AF transition which corresponds to the QCP, and finally to Kondo paramagnetic phase through a SC transition driven by localized-itinerant crossover. Our study gives a proper explanation for the pressure-induced magnetic QCP and SC transition, and for the phase-evolution process under pressure in typical Ce-based superconductors, and may also help to understand the SC states emerging around the ferromagnetic quantum transition points in uranium-based superconductors.Comment: 13 pages, 11 figure

    Poly[diaqua­(μ3-1H-benzimidazole-5,6-dicarboxyl­ato-κ4 N 3:O 5,O 6:O 6′)magnesium(II)]

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    In the title complex, [Mg(C9H4N2O4)(H2O)2]n, the MgII atom is six-coordinated by one N and three O atoms from three different 1H-benzimidazole-5,6-dicarboxyl­ate ligands and two O atoms from two water mol­ecules, forming a slightly distorted octa­hedral geometry. The ligand links the MgII centres into a three-dimensional network. Extensive N—H⋯O and O—H⋯O hydrogen bonds exist between the ligands and water mol­ecules, stabilizing the crystal structure
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