EVALUATION OF PRESCRIBING INDICATORS FOR PEADIATRIC OUTPATIENTS UNDER SIX YEARS OLD IN DISTRICT HOSPITALS OF CAN THO CITY IN THE PERIOD OF 2015-2016

Objective: Examining and comparing the primary and supplementary prescribing indicators in pediatric outpatients under six years old. Methods: We performed a comparative cross-sectional study, over nine months, from September 2015. 800 prescriptions for peadiatric patients under 6 y old were collected at 8 district hospitals in Can Tho city to evaluate the primary and supplementary prescribing indicators. The sample was collected prospectively by the systematic selection, with the interval between the patients is 5. The data was analysed and compared to the standard drug use indicators in developing countries recommended by WHO. Results: Average number of drugs per encounter: 4.1, percentage of drugs prescribed by generic name: 94.2%, percentage of encounters with an antibiotic prescribed: 85.8%, percentage of drugs prescribed from essential drugs list by Ministry of Health: 78.7%, percentage of encounters with a corticoid prescribed: 41.7%, percentage of encounters with a vitamin prescribed: 13.1%, average drug cost per encounter: 37.5 thousands VND, percentage of drug costs spent on antibiotics: 55.2%, percentage of drug costs spent on essential drugs: 75.7%, percentage of drug costs spent on corticoid: 1.9%, percentage of drug costs spent on vitamin: 1.4%. Conclusion: The results of this research have identified some issues in outpatient prescribing, which may lead to intervention studies for evaluating changes in these issues in the outpatient clinic

ANALYSIS OF PRESCRIPTION INDICATORS FOR OUTPATIENTS WITH HEALTH INSURANCE IN OUTPATIENTS DEPARTMENT AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN THE PERIOD 2017-2018

Objective: The main objective of this study was to evaluate the drug prescription parameters and to find out the elements had an influence on the prescribing practice of doctors’. Methods: A descriptive cross-sectional study was conducted to collect 300 outpatient drug prescriptions and 30 questionnaires of physicians during the period of 2017-2018. The data were analyzed according to WHO’s the guideline. Results: Average number of drug per prescription: 3.73, percentage of drugs prescribed by generic or international name (INN): 100%, percentage of prescriptions with an antibiotic prescribed: 24%, of β-lactam antibiotics group, including cephalosporin (31.17%) and aminopenicillin (27.27%), accounted for the highest percentage of using in antibiotic groups with a total of 58.44%, of corticosteroid: 12%, of vitamin: 27.3%, of drugs prescribed including in the Essential Medicines List issued by the Ministry of Health: 35.3%. Average drug cost per prescription: 88,867 VNĐ. Percentage of drug costs for antibiotics (%): 7.48%, of corticosteroids (%): 1.85% and of vitamins (%): 5.25%. Conclusion: The results of this research have identified some prescription indicators and elements affect the prescription indicators such as drug information, patient, drug, which may lead to intervention studies for evaluating changes in these issues in the outpatient clinic

Fundamental properties of Alkali-intercalated bilayer graphene nanoribbons

Along with the inherent remarkable properties of graphene, adatom-intercalated graphene-related systems are expected to exhibit tunable electronic properties. The metal-based atoms could provide multi-orbital hybridizations with the out-of-plane pi-bondings on the carbon honeycomb lattice, which dominates the fundamental properties of chemisorption systems. In this work, using the first-principles calculations, the feature-rich properties of alkali-metal intercalated graphene nanoribbons (GNRs) are investigated, including edge passivation, stacking configurations, intercalation sites, stability, charge density distribution, magnetic configuration, and electronic properties. There exists a transformation from finite gap semiconducting to metallic behaviors, indicating enhanced electrical conductivity. They arise from the cooperative or competitive relations among the significant chemical bonds, finite-size quantum confinement, edge structure, and stacking order. Moreover, the decoration of edge structures with hydrogen and oxygen atoms is considered to provide more information about the stability and magnetization due to the ribbon' effect. These findings will be helpful for experimental fabrications and measurements for further investigation of GNRs-based materials

Nurses' willingness to care for patients infected with HIV or Hepatitis B/C in Vietnam

Objectives: This study examined the factors associated with nurses' willingness to care for patients infected with human immunodeficiency virus (HIV) or hepatitis B or C virus (HBV/HCV) in Vietnam. Methods: A cross-section of 400 Vietnamese nurses from two hospitals were selected using stratified random sampling, to whom a self-administered questionnaire was administered which included demographic items, previous experience with patients infected with HIV or HBV/HCV, and their attitudes toward these patients. Data was analyzed using descriptive statistics and multiple logistic regression. Results: The lifetime prevalence of needlestick or sharps injury whilst caring for a patient infected with HIV or HBV/HCV was 9 and 15.8%, respectively. The majority of participants expressed a willingness to care for patients infected with HIV (55.8%) or HBV/HCV (73.3%). Willingness to care for HIV-infected patients was positively associated with being 40-49 years of age and confidence in protecting themselves against infection. Regarding HBV/HCV infection, willingness to care was positively associated with individual confidence in protecting themselves against infection. Conclusions: This study revealed that Vietnamese nurses were somewhat willing to care for patients infected with HIV or HBV/HCV, and this was associated with individual confidence in protecting themselves against infection and with negative attitudes towards HIV and HBV/HCV. Establishing a positive safety culture and providing appropriate professional education to help reduce the stigma towards infected patients offers an effective way forwards to improve quality of care in Vietnam, as elsewhere

Effects of plant essential oils and their constituents on Helicobacter pylori : A Review

Essential oils (EOs) obtained from different medicinal and aromatic plant families by steam distillation have been used in the pharmaceutical, food, and fragrance industries. The plant EOs and their broad diversity of chemical components have attracted researchers worldwide due to their human health benefits and antibacterial properties, especially their treatment of Helicobacter pylori infection. Since H. pylori has been known to be responsible for various gastric and duodenal diseases such as atrophic gastritis, peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma, several combination antibiotic therapies have been increasingly used to enhance the eradication rate of the bacterial infection. However, in the last decades, the efficacy of the therapies has decreased significantly due to widespread emergence of multidrug resistant strains of H. pylori. In addition, side-effects from commonly used antibiotics and recurrence of the bacterial infection have drawn public health concern globally.Therefore, this review focuses on in vitro effects of plant EOs and their bioactive constituents on the growth, cell morphology and integrity, biofilm formation, motility, adhesion, and urease activity of H. pylori. Their inhibitory effects on expression of genes necessary for growth and virulence factor productions of the bacterial pathogen are also discussed. Further in vivo and clinical evaluations are required so that plant EOs and their bioactive constituents can be possibly applicable in pharmacy or as adjuvants to the current therapies of H. pylori infection

CONTAMINATION BY PERSISTENT ORGANIC POLLUTANTS AND ENDOCRINE DISRUPTING CHEMICALS IN VIETNAM : PATTERNS, BEHAVIOR, TRENDS AND TOXIC POTENTIAL

Joint Research on Environmental Science and Technology for the Eart