37 research outputs found

    A prevalence of elevated ARR in rural Selangor

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    Abstract The objective of this study was to determine the prevalence of elevated Aldosterone Renin Ratio (ARR) in Rural Selangor. Methods This was a cross sectional study involving subjects in Kuala Selangor and Tanjung Karang. The World Health Survey Kish tables were used to select eligible subjects (≥18 years old) from each household. Their social demography, past medical history, anthropometric measurement and blood pressure were recorded. Blood were withdrawn for Aldosterone (ALD), Plasma Renin Activity (PRA), Creatinine (creat) and potassium (K). Raised ARR is defined as aldosterone/renin ratio of more than 20. Results A total of 392 subjects (age 55 +/- 14.1) were enrolled. Fourty three (11%) subjects showed an ARR > 20. Out of those with raised ARR, 16 (38%) were hypertensive, 2 of which were not taking any anti-hypertensive drugs and 27 subjects (62.8%) were normotensive. Only 2 (4.7%) of them were hypokalemic, one of them being hypertensive. Conclusion The prevalence of raised ARR in Rural Selangor was 11%, and only 4.7% of them were hypokalemic

    Prevalence of thyroid disorders and thyroid autoantibodies among coastal communities of Malaysia (part of nationwide study of thyroid disorders in Malaysia)

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    Objectives To determine the prevalence of thyroid disorders and thyroid autoantibodies in the coastal communities of Malaysia. This study is part of a nationwide study looking into the prevalence of thyroid disorders. Methods A cross sectional study was performed in two coastal districts of rural Selangor. A village from each district was chosen where a participant from each household from the village was selected using KISH tables. Sociodemographic data, medical history, anthropometric measurement and thyroid examination were performed. The presence of goiter was recorded according to the World Health Organization (WHO) goiter grading system. Blood withdrawn was tested for thyroid function and thyroid autoantibodies. Thyroid antibodies analyses were done using Immulite 2000 system. Lowest detectable limit for anti-thyroperoxidase (antiTPO) and antithyroglobulin (antiTG) are 10 IU/mL and 20 IU/mL respectively. Low, moderate and high titre is defined 40 - 100 IU/mL, 101-1000 IU/mL and >1000 IU/mL respectively. Results A total of 418 subjects were recruited with a mean age of 54.1 ± 14.2 years. Majority were Malays (86.8%), followed by Indians (11.7%) and Chinese (1.4%). Among respondents, 2.9% had Grade 1 and 8.9% had Grade 2 goitre. A mere 3.4% had clinically palpable thyroid nodules. A total of 411 blood samples were available for thyroid level assessment, with 1.9% of respondents were found to have hypothyroidism while 85.6% had TSH in the range of 0.32-2.5 mIU/L. The prevalence of overt and subclinical hypothyroidism was 0.2% and 1.7% AFES 2015 10 – 13 December 2015 respectively. On the otherhand, 3.4% of respondents were hyperthyroid (TSH < 0.32 mIU/L) with prevalence of overt and subclinical hyperthyroidism being 0.5% and 2.9% respectively. Among 417 samples which were available for antiTPO analysis, 8.9% has detectable antiTPO titre (>40.0 IU/mL), with 4.3% had moderate and 2.4% had high antiTPO titres. One respondent (10%) from among those with high antiTPO titres was found to have T3 thyrotoxicosis. Fourty percent of euthyroid respondents with high titre and 38.9% with moderate titre had high normal TSH, in the range of 2.51 – 5.00 mIU/L (p<0.001). Among 417 samples which are available for antiTG analysis, 3.4% and 5.3% had low detectable and moderate antiTG titres respectively. Only 0.5% (2 respondents) had high antiTG titre (>1000 IU/mL) and found to be hypothyroid. Among those with moderately positive titre, 9.1% were hyperthyroid and majority (63.6%), although euthyroid, had TSH levels between 0.32 – 2.50 mIU/L (p<0.001). Conclusion The low prevalence of thyroid antibodies and thyroid disorders in coastal communities could be attributed to the iodine sufficient status in those areas. Euthyroid respondents with moderate and high antiTPO titres tend to have higher TSH levels, while those with moderate and high antiTG titres had lower TSH levels

    Prevalence, awareness and control of hypertension in rural areas in Selangor and Perak

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    Abstract The aim of this study was to describe the prevalence, awareness and control of hypertension in the rural population of Perak and Selangor. Methods This was a population based cross-sectional study involving subjects in Kuala Selangor, Tanjung Karang and Bidor. The World Health Survey Kish tables were used to select eligible subject (≥18 years old) from each selected household. A Case Report Form (CRF) was used to record their social demography, past medical history, anthropometry measurement and blood pressure (BP). Hypertension was defined as a blood pressure > 140/90 mmHg. Hypertension controlled was defined as a blood pressure of < 140/90 mmHg. Results A total of 761 people participated in this study. Of which 287 (37.8%) were males and 473 (62.2%) were females. Out of this, 271 (35.6%) were hypertensive. The study showed 36 (4.7%) subjects were not aware that they have hypertension. Only 76% of hypertensive subjects were on HPT medication. One hundred and five (51%) subjects were on monotherapy, 66 (32%) were on dual therapy, 27 (13.1%) on triple therapy, 8 (3.9%) were on more than 3 medications. 73 (26.9%) of the hypertensive subjects were not on any HPT medications having a SBP of 133.9 +/- 17 and DBP of 86.2 +/- 49.3

    Variations in fatty acids composition of pikeperch (Sander lucioperca) liver with respect to gonad maturation

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    We examined seasonal variations in liver condition factor, total lipid and fatty acid composition of maturing pikeperch (Sander lucioperca) from Lake Egirdir, Turkey. The spawning of pikeperch in Egirdir Lake started in March, continued very fast during May and gradually ended in July as determined by measuring the gonadosomatic index. The total lipid content of male and female liver reached its highest level in September and November (the end of dense feeding period during which temperature decreased sharply), but declined to the lowest level in May Oust after spawning). The highest level of liver condition factor was observed in January and March during which gonads mature rapidly. Palmitic acid was the predominant saturated fatty acid (SFA) in female and male liver. The ratio of monounsaturated fatty acids (MUFA) was higher than that of polyunsaturated fatty acids (PUFA) in both sexes. Docosahexaenoic acid (22:6n-3), eicosopentaenoic acid (20:5n-3) and arachidonic acid (20:4n-6) were the predominant PUFA. Seasonal variations in PUFA were more evident than that in other fatty acids. PUFA, especially the n-3 fatty acids ratio, increased to the maximum level during the sharp decreases in temperature (in November). However, the amount of PUFA decreased to the lowest level in reproductive period. The results suggest that the ratio of pikeperch liver fatty acids is influenced by gonad maturation and temperature variations and that pikeperch requires a large amount of PUFA and the n-3 fatty acids for the development of gonads

    Energy Procedia

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    Advanced hydrogenation processes targeting the generation of neutrally charged hydrogen (H°) are applied to passivate structural defects in seeded-cast quasi mono-crystalline silicon wafers and boron-oxygen defects in Czochralski silicon. The application of a one minute laser hydrogenation process onto a finished screen printed solar cell fabricated on the dislocation-rich seeded-cast material resulted in efficiency enhancements of 0.6% absolute through improvements in the implied open circuit voltage and internal quantum efficiency in the vicinity of the dislocated regions. A new insight is presented on the formation of boron-oxygen defects with a strong dependence on illumination intensity. An advanced laser hydrogenation process is presented to rapidly form and hydrogenate boron-oxygen defects simultaneously, in an 8 s process applied directly after belt furnace firing, with the hydrogenation of more than 95% of boron-oxygen defects at a peak temperature of approximately 360°C on lifetime test structures. The same 8 s process is also demonstrated on standard screen-printed solar cells applied directly after belt furnace firing to simultaneously form- and hydrogenate the boron-oxygen defects, with no subsequent loss in electrical performance, hence avoiding a 0.7% absolute loss in efficiency due to light-induced degradation

    Meal patterns of Malaysian adults: Findings from the Malaysian adults nutrition survey (MANS)

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    Introduction: Meal patterns have received little attention in nutrition studies. The aim of this study is to present the findings on general meal patterns of Malaysian adults. Methods: The Malaysian Adults Nutrition Survey (MANS), carried out in 2002 and 2003, involved 6,928 adults selected by stratified random sampling from all households by zone in Peninsular Malaysia, Sabah and Sarawak. Results: In general, the results showed that most respondents (74.16%) ate three meals per day; 89.20% of the respondents consumed breakfast, while 88.57% consumed lunch and 91.97% consumed dinner with no significant difference in terms of sex. In Peninsular Malaysia, the Northern Zone had the highest number of people consuming breakfast compared to other zones. Meanwhile, the population in Sarawak had the largest proportion of people consuming lunch and dinner, but the smallest proportion of people consuming breakfast. A significantly higher number of the rural population consumed breakfast and lunch than urbanites; however there was no significant difference in dinner consumption. Generally, breakfast consumption increased with age whereby significant difference existed between the 18 to 19 years age group and the age group of 30 years and older. Lunch intake among the age groups showed no significant difference. In contrast, dinner consumption was significantly lower among the 18 to 19 years age group compared to all other age groups. Comparison among the ethnic groups showed that the Indian population had the lowest percentage of having breakfast and lunch while the Orang Asli had the lowest percentage of consuming dinner. However, the Orang Asli recorded the highest percentage for taking breakfast and lunch while the Chinese had the highest percentage of taking dinner. Conclusion: Considering that Malaysian adults consumed their conventional breakfast, lunch and dinner, these findings indicatethat Malaysians are maintaining their traditional meal patterns

    Prevalence of elevated aldosterone renin ratio in three main states of Peninsular Malaysia

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    Objective: The objective of this study was to determine the prevalence of increased Aldosterone Renin Ratio (ARR) in parts of Selangor, Perak and Pahang. Methods: This was a cross sectional study involving subjects in Selangor, Perak and Pahang. The World Health Survey Kish tables were used to select eligible subjects (≥18 years old) from each household. Their social demography, past medical history, anthropometric measurement and blood pressure were recorded. Blood were withdrawn for Aldosterone (ALD), Plasma Renin Activity (PRA), Creatinine (creat) and potassium (K). Raised ARR is defined as aldosterone/renin ratio of more than 20. Results: A total of 1073 subjects (age 50 +/- 16.4). One hundred and nineteen (11.1%) subjects showed an ARR =/> 20. Forty nine (41.2%) out of the elevated ARR =/> 20 were hypertensive, 11 of which were not taking any anti-hypertensive drugs and 54 subjects (45.4%) were normotensive. Only 7 (5.9%) of them were hypokalemic, one of them being hypertensive. The main clinical characteristics of subjects with raised ARR are shown in Table 1. Conclusion: The prevalence of raised ARR in Rural Selangor was 11.1%, and only 5.9% of them were hypokalemic
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