5 research outputs found
Wildlife Reservoirs of Canine Distemper Virus Resulted in a Major Outbreak in Danish Farmed Mink (<em>Neovison vison</em>)
A major outbreak of canine distemper virus (CDV) in Danish farmed mink (Neovison vison) started in the late summer period of 2012. At the same time, a high number of diseased and dead wildlife species such as foxes, raccoon dogs, and ferrets were observed. To track the origin of the outbreak virus full-length sequencing of the receptor binding surface protein hemagglutinin (H) was performed on 26 CDV's collected from mink and 10 CDV's collected from wildlife species. Subsequent phylogenetic analyses showed that the virus circulating in the mink farms and wildlife were highly identical with an identity at the nucleotide level of 99.45% to 100%. The sequences could be grouped by single nucleotide polymorphisms according to geographical distribution of mink farms and wildlife. The signaling lymphocytic activation molecule (SLAM) receptor binding region in most viruses from both mink and wildlife contained G at position 530 and Y at position 549; however, three mink viruses had an Y549H substitution. The outbreak viruses clustered phylogenetically in the European lineage and were highly identical to wildlife viruses from Germany and Hungary (99.29% β 99.62%). The study furthermore revealed that fleas (Ceratophyllus sciurorum) contained CDV and that vertical transmission of CDV occurred in a wild ferret. The study provides evidence that wildlife species, such as foxes, play an important role in the transmission of CDV to farmed mink and that the virus may be maintained in the wild animal reservoir between outbreaks
The 2000 canine distemper epidemic in Caspian seals (Phoca caspica): pathology and analysis of contributory factors
ΠΠ»Π΅ΠΊΡΡΠΎΠ½Π½ΡΠ΅ ΠΈ ΠΏΠΎΠ·ΠΈΡΡΠΎΠ½Π½ΡΠ΅ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π² ΡΠ»ΠΎΠΈΡΡΡΡ Π½Π°Π½ΠΎΡΡΡΡΠΊΡΡΡΠ°Ρ Β«ΠΌΠ΅ΡΠ°Π»Π» β Π΄ΠΈΡΠ»Π΅ΠΊΡΡΠΈΠΊΒ»
Π ΡΠ°ΠΌΠΊΠ°Ρ
ΠΌΠΎΠ΄ΠΈΡΡΠΊΠΎΠ²Π°Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΠΎΠ½Π° β Π¨Π΅ΠΌΠ° Ρ ΠΌΠΎΠ΄Π΅Π»Ρ ΡΡΠ°Π±ΡΠ»ΡΠ½ΠΎΠ³ΠΎ ΠΆΠ΅Π»Π΅ Π· ΡΡΠ°Ρ
ΡΠ²Π°Π½Π½ΡΠΌ ΡΠΈΠ» Π΄Π·Π΅ΡΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½Π½Ρ Ρ Π·ΠΎΠ½ΠΈ ΠΏΡΠΎΠ²ΡΠ΄Π½ΠΎΡΡΡ Π΄ΡΠ΅Π»Π΅ΠΊΡΡΠΈΠΊΠ° Π²ΠΈΠΊΠΎΠ½Π°Π½Ρ ΡΠ°ΠΌΠΎΡΠ·Π³ΠΎΠ΄ΠΆΠ΅Π½Ρ ΡΠΎΠ·ΡΠ°Ρ
ΡΠ½ΠΊΠΈ ΠΏΡΠΎΡΡΠ»ΡΠ² ΠΏΠΎΡΠ΅Π½ΡΡΠ°Π»ΡΠ², ΡΠΎΠ±ΡΡ Π²ΠΈΡ
ΠΎΠ΄Ρ Ρ Π±Π°ΡβΡΡΡΠ² Π¨ΠΎΡΡΠΊΡ Π΄Π»Ρ Π°ΡΠΈΠΌΠ΅ΡΡΠΈΡΠ½ΠΈΡ
ΠΌΠ΅ΡΠ°Π»-Π΄ΡΠ΅Π»Π΅ΠΊΡΡΠΈΡΠ½ΠΈΡ
ΠΏΠ»ΡΠ²ΠΊΠΎΠ²ΠΈΡ
ΡΠΈΡΡΠ΅ΠΌ, Π² ΡΠΊΠΈΡ
Π΄ΡΠ΅Π»Π΅ΠΊΡΡΠΈΠΊΠΈ ΠΏΠΎ ΠΎΠ±ΠΈΠ΄Π²Π° Π±ΠΎΠΊΠΈ Π²ΡΠ΄ Π½Π°Π½ΠΎΠΏΠ»ΡΠ²ΠΊΠΈ ΠΌΠ΅ΡΠ°Π»Ρ ΡΡΠ·Π½Ρ. ΠΡΠ΅Π»Π΅ΠΊΡΡΠΈΡΠ½Π΅ ΠΎΡΠΎΡΠ΅Π½Π½Ρ Π² ΡΡΠ»ΠΎΠΌΡ ΠΏΡΠΈΠ·Π²ΠΎΠ΄ΠΈΡΡ Π΄ΠΎ Π½Π΅Π³Π°ΡΠΈΠ²Π½ΠΎΡ Π·ΠΌΡΠ½ΠΈ ΡΠΎΠ±ΠΎΡΠΈ Π²ΠΈΡ
ΠΎΠ΄Ρ Π΅Π»Π΅ΠΊΡΡΠΎΠ½ΡΠ² Ρ ΠΏΠΎΠ²Π΅ΡΡ
Π½Π΅Π²ΠΎΡ Π΅Π½Π΅ΡΠ³ΡΡ. Π ΡΡΠ°Ρ
ΡΠ²Π°Π½Π½ΡΠΌ Π·ΠΎΠ½ΠΈ ΠΏΡΠΎΠ²ΡΠ΄Π½ΠΎΡΡΡ Π΄ΡΠ΅Π»Π΅ΠΊΡΡΠΈΠΊΠ° (ΡΠ²Π΅ΡΠ΄Ρ ΡΠ½Π΅ΡΡΠ½Ρ Π³Π°Π·ΠΈ, ) Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½ΠΎ ΡΠΎΠ·ΠΌΡΡΠ½Ρ Π΅ΡΠ΅ΠΊΡΠΈ, Π²ΠΏΠ»ΠΈΠ² Π΅ΡΠ΅ΠΊΡΠΈΠ²Π½ΠΈΡ
ΠΌΠ°Ρ Π½Π° Π΅Π½Π΅ΡΠ³Π΅ΡΠΈΡΠ½Ρ ΡΠ° Π°Π½ΡΠ³ΡΠ»ΡΡΡΠΉΠ½Ρ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΠΏΠΎΠ·ΠΈΡΡΠΎΠ½ΡΠ² Ρ ΡΠ°ΡΡΠ²Π°ΡΠΈΡ
ΡΡΡΡΠΊΡΡΡΠ°Ρ
ΡΠ· ΡΠ°ΠΌΠΎΡΠ·Π³ΠΎΠ΄ΠΆΠ΅Π½ΠΈΠΌΠΈ Π³ΡΠ±ΡΠΈΠ΄Π½ΠΈΠΌΠΈ ΠΏΠΎΡΠ΅Π½ΡΡΠΉΠ½ΠΈΠΌΠΈ ΠΏΡΠΎΡΡΠ»ΡΠΌΠΈ, ΠΏΠΎΠ±ΡΠ΄ΠΎΠ²Π°Π½ΠΈΠΌΠΈ Π² Π½Π°Π±Π»ΠΈΠΆΠ΅Π½Π½Ρ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΡ Π³ΡΡΡΠΈΠ½ΠΈ Ρ Π·ΡΠΈΡΠΈΠΌΠΈ Π· ΠΏΠΎΡΠ΅Π½ΡΡΠ°Π»Π°ΠΌΠΈ Π΄Π·Π΅ΡΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½Π½Ρ. ΠΠ±Π³ΠΎΠ²ΠΎΡΡΡΡΡΡΡ ΠΌΠΎΠΆΠ»ΠΈΠ²ΡΡΡΡ Π»ΠΎΠΊΠ°Π»ΡΠ·Π°ΡΡΡ Π°ΡΠΎΠΌΠ° ΠΏΠΎΠ·ΠΈΡΡΠΎΠ½ΡΡ Π² Π½Π°Π½ΠΎΡΠ°Π½Π΄Π²ΡΡΠ°Ρ
. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΠΏΠΎΡΡΠ²Π½ΡΠ½Π½Ρ Π· Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°ΠΌΠΈ.Π ΡΠ°ΠΌΠΊΠ°Ρ
ΠΌΠΎΠ΄ΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΠΎΠ½Π° β Π¨Π΅ΠΌΠ° ΠΈ ΠΌΠΎΠ΄Π΅Π»ΠΈ ΡΡΠ°Π±ΠΈΠ»ΡΠ½ΠΎΠ³ΠΎ ΠΆΠ΅Π»Π΅ Ρ ΡΡΠ΅ΡΠΎΠΌ ΡΠΈΠ» Π·Π΅ΡΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡ ΠΈ Π·ΠΎΠ½Ρ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΡΡΠΈ Π΄ΠΈΡΠ»Π΅ΠΊΡΡΠΈΠΊΠ° Π²ΡΠΏΠΎΠ»Π½Π΅Π½Ρ ΡΠ°ΠΌΠΎΡΠΎΠ³Π»Π°ΡΠΎΠ²Π°Π½Π½ΡΠ΅ ΡΠ°ΡΡΠ΅ΡΡ ΠΏΡΠΎΡΠΈΠ»Π΅ΠΉ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΠΎΠ², ΡΠ°Π±ΠΎΡ Π²ΡΡ
ΠΎΠ΄Π° ΠΈ Π±Π°ΡΡΠ΅ΡΠΎΠ² Π¨ΠΎΡΡΠΊΠΈ Π΄Π»Ρ Π°ΡΠΈΠΌΠΌΠ΅ΡΡΠΈΡΠ½ΡΡ
ΠΌΠ΅ΡΠ°Π»Π»-Π΄ΠΈΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΠ»Π΅Π½ΠΎΡΠ½ΡΡ
ΡΠΈΡΡΠ΅ΠΌ, Π² ΠΊΠΎΡΠΎΡΡΡ
Π΄ΠΈΡΠ»Π΅ΠΊΡΡΠΈΠΊΠΈ ΠΏΠΎ ΠΎΠ±Π΅ ΡΡΠΎΡΠΎΠ½Ρ Π½Π°Π½ΠΎΠΏΠ»Π΅Π½ΠΊΠΈ ΠΌΠ΅ΡΠ°Π»Π»Π° ΡΠ°Π·Π½ΡΠ΅. ΠΠΈΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΎΠΊΡΡΠΆΠ΅Π½ΠΈΡ Π² ΡΠ΅Π»ΠΎΠΌ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ Π½Π΅Π³Π°ΡΠΈΠ²Π½ΠΎΠΌΡ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΠ°Π±ΠΎΡΡ Π²ΡΡ
ΠΎΠ΄Π° ΡΠ»Π΅ΠΊΡΡΠΎΠ½ΠΎΠ² ΠΈ ΠΏΠΎΠ²Π΅ΡΡ
Π½ΠΎΡΡΠ½ΠΎΠΉ ΡΠ½Π΅ΡΠ³ΠΈΠΈ. Π‘ ΡΡΠ΅ΡΠΎΠΌ Π·ΠΎΠ½Ρ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΡΡΠΈ Π΄ΠΈΡΠ»Π΅ΠΊΡΡΠΈΠΊΠ° (ΡΠ²Π΅ΡΠ΄ΡΠ΅ ΠΈΠ½Π΅ΡΡΠ½ΡΠ΅ Π³Π°Π·Ρ, ) ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Ρ ΡΠ°Π·ΠΌΠ΅ΡΠ½ΡΠ΅ ΡΡΡΠ΅ΠΊΡΡ, Π²Π»ΠΈΡΠ½ΠΈΠ΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΠΌΠ°ΡΡ Π½Π° ΡΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ Π°Π½Π½ΠΈΠ³ΠΈΠ»ΡΡΠΈΠΎΠ½Π½ΡΠ΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΠΏΠΎΠ·ΠΈΡΡΠΎΠ½ΠΎΠ² Π² ΡΠ»ΠΎΠΈΡΡΡΡ
ΡΡΡΡΠΊΡΡΡΠ°Ρ
Ρ ΡΠ°ΠΌΠΎΡΠΎΠ³Π»Π°ΡΠΎΠ²Π°Π½Π½ΡΠΌΠΈ Π³ΠΈΠ±ΡΠΈΠ΄Π½ΡΠΌΠΈ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΏΡΠΎΡΠΈΠ»ΡΠΌΠΈ, ΠΏΠΎΡΡΡΠΎΠ΅Π½Π½ΡΠΌΠΈ Π² ΠΏΡΠΈΠ±Π»ΠΈΠΆΠ΅Π½ΠΈΠΈ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΠΈ ΠΈ ΡΡΠΈΡΡΠΌΠΈ Ρ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Π°ΠΌΠΈ Π·Π΅ΡΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡ. ΠΠ±ΡΡΠΆΠ΄Π°Π΅ΡΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π°ΡΠΎΠΌΠ° ΠΏΠΎΠ·ΠΈΡΡΠΎΠ½ΠΈΡ Π² Π½Π°Π½ΠΎΡΠ°Π½Π΄Π²ΠΈΡΠ°Ρ
. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ Ρ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°ΠΌΠΈ.Within the framework of modified method of Kohn-Sham and stable jelly model with taking into account image forces and conduction band profiles of the dielectric self-consistent calculations of potential profiles, and the work functions, the Schottky barriers for asymmetric metal dielectric film systems in which insulators on both sides of the metal nanofilms are different were done. Dielectric environment generally leads to negative changes in the electron work function and surface energy. In view of the conduction band of the dielectric (solid inert gases, ) dimensional effects, the impact of effective mass to energy and positron annihilation characteristics in layered structures with self-consistent hybrid potential profiles, which built in the local density approximation and crosslinked with image potentials were investigated. The possibility of localization of positronium atoms in nanosandvich is discussed. Comparison with the experiments were done