Tilted accretion discs in cataclysmic variables: tidal instabilities and superhumps

We investigate the growth of tidal instabilities in accretion discs in a binary star potential, using three dimensional numerical simulations. As expected from analytic work, the disc is prone to an eccentric instability provided that it is large enough to extend to the 3:1 resonance. The eccentric disc leads to positive superhumps in the light curve. It has been proposed that negative superhumps might arise from a tilted disc, but we find no evidence that the companion gravitational tilt instability can grow fast enough in a fluid disc to create a measurable inclination. The origin of negative superhumps in the light curves of cataclysmic variables remains a puzzle.Comment: 7 pages, 7 figures, accepted for publication in MNRA

On a dynamic reaction-diffusion mechanism: The spatial patterning of teeth primordia in the alligator

It is now well established both theoretically and, more recently, experimentally, that steady-state spatial chemical concentration patterns can be formed by a number of specific reaction–diffusion systems. Reaction–diffusion models have been widely applied to biological pattern formation problems. Here we propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator, Alligator mississippiensis, which, from a reaction–diffusion theory, introduces, among other things, a new element, namely the effect of domain growth on dynamic spatial pattern formation. Detailed embryological studies by Westergaard and Ferguson (B. Westergaard and M. W. J. Ferguson, J. Zool. Lond., 1986, 210, 575; 1987, 212, 191; Am. J. Anatomy, 1990, 187, 393) show that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a reaction–diffusion mechanism, which crucially includes domain growth. The model can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw of A. mississippiensis. The results for the precise spatio temporal sequence compare well with detailed developmental experiments

Selenium reagents in organic synthesis

Imperial Users onl

Modelling delta-notch perturbations during zebrafish somitogenesis

The discovery over the last 15 years of molecular clocks and gradients in the pre-somitic mesoderm of numerous vertebrate species has added significant weight to Cooke and Zeeman's ‘clock and wavefront’ model of somitogenesis, in which a travelling wavefront determines the spatial position of somite formation and the somitogenesis clock controls periodicity (Cooke and Zeeman, 1976). However, recent high-throughput measurements of spatiotemporal patterns of gene expression in different zebrafish mutant backgrounds allow further quantitative evaluation of the clock and wavefront hypothesis. In this study we describe how our recently proposed model, in which oscillator coupling drives the propagation of an emergent wavefront, can be used to provide mechanistic and testable explanations for the following observed phenomena in zebrafish embryos: (a) the variation in somite measurements across a number of zebrafish mutants; (b) the delayed formation of somites and the formation of ‘salt and pepper’ patterns of gene expression upon disruption of oscillator coupling; and (c) spatial correlations in the ‘salt and pepper’ patterns in Delta-Notch mutants. In light of our results, we propose a number of plausible experiments that could be used to further test the model

Analog communication over selective fading channels Interim technical report

Demodulators for analog communication over slowly time varying, frequency selective fading channel

On the quasi-steady state assumption applied to Michaelis-Menten and suicide substrate reactions with diffusion

We consider a recent extension to the validity of the quasi-steady-state assumption (QSSA) which includes the case where the ratio of the initial enzyme to substrate concentration is not necessarily small. We extend the analysis to include diffusion of substrate, in which case the initial enzyme to substrate ratio is spatially dependent and no longer constant. We show that the region in which the QSSA holds depends on the nature of the enzyme-substrate reaction: if the enzyme is inactivated by the substrate then the QSSA holds in a growing disc; if the enzyme is unchanged after reaction then the QSSA holds in a ring travelling through space

A computer vision approach to classification of birds in flight from video sequences

Bird populations are an important bio-indicator; so collecting reliable data is useful for ecologists helping conserve and manage fragile ecosystems. However, existing manual monitoring methods are labour-intensive, time-consuming, and error-prone. The aim of our work is to develop a reliable system, capable of automatically classifying individual bird species in flight from videos. This is challenging, but appropriate for use in the field, since there is often a requirement to identify in flight, rather than when stationary. We present our work in progress, which uses combined appearance and motion features to classify and present experimental results across seven species using Normal Bayes classifier with majority voting and achieving a classification rate of 86%

Travelling waves in a tissue interaction model for skin pattern formation

Tissue interaction plays a major role in many morphogenetic processes, particularly those associated with skin organ primordia. We examine travelling wave solutions in a tissue interaction model for skin pattern formation which is firmly based on the known biology. From a phase space analysis we conjecture the existence of travelling waves with specific wave speeds. Subsequently, analytical approximations to the wave profiles are derived using perturbation methods. We then show numerically that such travelling wave solutions do exist and that they are in good agreement with our analytical results. Finally, the biological implications of our analysis are discussed

Suicide substrate reaction-diffusion equations: varying the source

The suicide substrate reaction is a model for certain enzyme-inhibiting drugs. This reaction system is examined assuming that the substrate diffuses freely while the enzyme remains fixed. Two sets of initial and boundary conditions are examined: one modelling an instantaneous point source, akin to an injection of substrate, the other, a continuous point source, akin to a continuing influx, or intravenous drip, of substrate. The quasi-steady-state assumption is applied to obtain analytical solutions for a limited parameter space. Finally, further applications of numerical and analytical experimentation on pharmaceutical mechanisms are described

The effects of tidally induced disc structure on white dwarf accretion in intermediate polars

We investigate the effects of tidally induced asymmetric disc structure on accretion onto the white dwarf in intermediate polars. Using numerical simulation, we show that it is possible for tidally induced spiral waves to propagate sufficiently far into the disc of an intermediate polar that accretion onto the central white dwarf could be modulated as a result. We suggest that accretion from the resulting asymmetric inner disc may contribute to the observed X-ray and optical periodicities in the light curves of these systems. In contrast to the stream-fed accretion model for these periodicities, the tidal picture predicts that modulation can exist even for systems with weaker magnetic fields where the magnetospheric radius is smaller than the radius of periastron of the mass transfer stream. We also predict that additional periodic components should exist in the emission from low mass ratio intermediate polars displaying superhumps.Comment: 9 pages, 5 figures, accepted for publication in MNRA