The supersymmetric Ward identities on the lattice

Supersymmetric (SUSY) Ward identities are considered for the N=1 SU(2) SUSY Yang Mills theory discretized on the lattice with Wilson fermions (gluinos). They are used in order to compute non-perturbatively a subtracted gluino mass and the mixing coefficient of the SUSY current. The computations were performed at gauge coupling $\beta$=2.3 and hopping parameter $\kappa$=0.1925, 0.194, 0.1955 using the two-step multi-bosonic dynamical-fermion algorithm. Our results are consistent with a scenario where the Ward identities are satisfied up to O(a) effects. The vanishing of the gluino mass occurs at a value of the hopping parameter which is not fully consistent with the estimate based on the chiral phase transition. This suggests that, although SUSY restoration appears to occur close to the continuum limit of the lattice theory, the results are still affected by significant systematic effects.Comment: 34 pages, 7 figures. Typo corrected, last sentence reformulated, reference added. To appear in Eur. Phys. J.

Sequence analysis and genomic organization of Aphid lethal paralysis virus: a new member of the family Dicistroviridae

The complete nucleotide sequence of the genomic RNA of an aphid-infecting virus, Aphid lethal paralysis virus (ALPV), has been determined. The genome is 9812 nt in length and contains two long open reading frames (ORFs), which are separated by an intergenic region of 163 nt. The first ORF (5' ORF) is preceded by an untranslated leader sequence of 506 nt, while an untranslated region of 571 nt follows the second ORF (3' ORF). The deduced amino acid sequences of the 5' ORF and 3' ORF products respectively showed similarity to the non-structural and structural proteins of members of the newly recognized genus Cripavirus (family Dicistroviridae). On the basis of the observed sequence similarities and identical genome organization, it is proposed that ALPV belongs to this genus. Phylogenetic analysis showed that ALPV is most closely related to Rhopalosiphum padi virus, and groups in a cluster with Drosophila C virus and Cricket paralysis virus, while the other members of this genus are more distantly related. Infectivity experiments showed that ALPV can not only infect aphid species but is also able to infect the whitefly Trialeurodes vaporariorum, extending its host range to another family of the order Hemipter

Monte Carlo simulation of SU(2) Yang-Mills theory with light gluinos

In a numerical Monte Carlo simulation of SU(2) Yang-Mills theory with light dynamical gluinos the low energy features of the dynamics as confinement and bound state mass spectrum are investigated. The motivation is supersymmetry at vanishing gluino mass. The performance of the applied two-step multi-bosonic dynamical fermion algorithm is discussed.Comment: latex, 48 pages, 16 figures with epsfi

Temporal trends in safety of carotid endarterectomy in asymptomatic patients

Objective: To systematically review temporal changes in perioperative safety of carotid endarterectomy (CEA) in asymptomatic individuals in trial and registry studies. Methods: The MEDLINE and EMBASE databases were searched using the terms “carotid” and “endarterectomy” and “asymptomatic” from 1947 to August 23, 2014. Articles dealing with 50%–99% stenosis in asymptomatic individuals were included and low-volume studies were excluded. The primary endpoint was 30-day stroke or death and the secondary endpoint was 30-day all-cause mortality. Statistical analysis was performed using random-effects meta-regression for registry data and for trial data graphical interpretation alone was used. Results: Six trials (n = 4,431 procedures) and 47 community registries (n = 204,622 procedures) reported data between 1983 and 2013. Registry data showed a significant decrease in postoperative stroke or death incidence over the period 1991–2010, equivalent to a 6% average proportional annual reduction (95% credible interval [CrI] 4%–7%; p < 0.001). Considering postoperative all-cause mortality, registry data showed a significant 5% average proportional annual reduction (95% CrI 3%–9%; p < 0.001). Trial data showed a similar visual trend. Conclusions: CEA is safer than ever before and high-volume registry results closely mirror the results of trials. New benchmarks for CEA are a stroke or death risk of 1.2% and a mortality risk of 0.4%. This information will prove useful for quality improvement programs, for health care funders, and for those re-examining the long-term benefits of asymptomatic revascularization in future trials

Immunohistochemical Demonstration of IgG in Reed-Sternberg and Other Cells in Hodgkin\u27s Disease

Increased synthesis of IgG in vitro has been demonstrated in spleens from patients with Hodgkin\u27s disease, either with or without invasion of the organ by tumor (1). Interest in this laboratory has centered recently on cytochemical localization of immunoglobulins by means of an immunoglobulin-peroxidase bridge procedure (2) and a satisfactory method has been developed for selectively visualizing immunocytes with this technique. 1 As a means of assessing the basis for increased IgG biosynthesis in spleens of Hodgkin patients, this immunostaining procedure has been applied to localization of IgG-producing cells in specimens with Hodgkin\u27s disease

Implementation of Model-Based Design of Experiments: Application of Computational Modeling to Support HRP Studies

This study illustrates the potential gains obtained by leveraging computational modeling to improve experimental efficiency in NASA research and counter measures studies through implementation of Model-Based Design of Experiments (MBDOE). MBDOE is a method to utilize analogous computational models to improve understanding of complex, multifactor, experimental responses and to determine experimental conditions and optimize information in the fewest number of experimental tests