106 research outputs found
Real-time marker-less multi-person 3D pose estimation in RGB-Depth camera networks
This paper proposes a novel system to estimate and track the 3D poses of
multiple persons in calibrated RGB-Depth camera networks. The multi-view 3D
pose of each person is computed by a central node which receives the
single-view outcomes from each camera of the network. Each single-view outcome
is computed by using a CNN for 2D pose estimation and extending the resulting
skeletons to 3D by means of the sensor depth. The proposed system is
marker-less, multi-person, independent of background and does not make any
assumption on people appearance and initial pose. The system provides real-time
outcomes, thus being perfectly suited for applications requiring user
interaction. Experimental results show the effectiveness of this work with
respect to a baseline multi-view approach in different scenarios. To foster
research and applications based on this work, we released the source code in
OpenPTrack, an open source project for RGB-D people tracking.Comment: Submitted to the 2018 IEEE International Conference on Robotics and
Automatio
Clinical trials for elderly patients with multiple diseases (CHROMED) pilot study
The problem
COPD (Chronic Obstructive Pulmonary Disease) is a significant socioeconomic burden which, particularly when associated with comorbidities such as Chronic Heart Failure (CHF), markedly affects patient outcomes. Care models based on telemedicine systems that enable early diagnosis and treatment of exacerbations are advocated to reduce the impact of chronic diseases on patient outcomes and health service costs. CHROMED (www.chromed.eu) is an international EU-funded project aimed at developing a multi-centre clinical trial to evaluate the impact of a new integrated home care approach to reduce care costs and improve quality of life in COPD.
The approach
We collaborated in a pilot study prior to the main trial which will include 300 patients from seven European countries (Italy, Spain, UK, Estonia, Slovenia, Sweden and Norway) with nine partners. The home monitoring system includes a novel forced oscillation technique (FOT) device for self-measurement of lung mechanics (RESMONPRO DIARY, Restech srl, Italy), a touch screen for collecting patients' symptoms and, where COPD is associated with CHF, by a device for measuring heart rate (HR), blood pressure (BP), pulse oximetry (SpO2) and body temperature (WRIST CLINIC, Medic4all, Israel).
Findings
The pilot included 16 patients (n=11 COPD, 5 COPD+CHF). The average monitoring period was 48.3±23.4 days resulting in a total of 504 patient days. The percentage of data correctly received within the period was: lung impedance and breathing pattern 90.0%; HR 91.7%, BP 91.7%; SpO2 74.0% and body temperature 71.4%. During the pilot, one patient was treated pharmacologically for an exacerbation of COPD. Offline processing demonstrated that the system identified warning of an exacerbation five days prior to admission. We also analysed qualitative data from patients and professionals about the acceptability of the telemedicine system and the interaction between patients, professionals and the monitoring system.
Consequences
The data suggest good acceptability and short-term compliance among patients with COPD. Lung function, HR and BP provided the most reliable data. The full RCT is currently under way and will be completed in August 2015
Σχεδιασμός κοχλιοφόρου αντλίας κονιαμάτων με μεταβλητή διατομή
Crop growth simulation models require robust ecophysiological functionality to support credible simulation of diverse genotype × management × environment (G × M × E) combinations. Most efforts on modeling the nitrogen (N) dynamics of crops use a minimum, critical, and maximum N concentration per unit biomass based empirically on experimental observations. Here we present a physiologically more robust approach, originally implemented in sorghum, which uses the N content per unit leaf area as a key driver of N demand. The objective was to implement the conceptual framework of the APSIM sorghum nitrogen dynamics model in APSIM maize and to validate the robustness of the model across a range of G × M × E combinations. The N modelling framework is described and its parameterisation for maize is developed based on three previously reported detailed field experiments, conducted at Gatton (27°34'S, 152°20'), Queensland, Australia, supplemented by literature data. There was considerable correspondence with parameterisation results found for sorghum, suggesting potential for generality of this framework for modelling crop N dynamics in cereals. Comprehensive model testing indicated accurate predictions at organ and crop scale across a diverse range of experiments and demonstrated that observed responses to a range of management factors were reproduced credibly. This supports the use of the model to extrapolate and predict performance and adaptation under new G × M × E combinations. Capturing this advance with reduced complexity compared to the N concentration approach provides a firm basis to progress the role of modelling in exploring the genetic underpinning of complex traits and in plant breeding and crop improvement generally
Estabilidade genética em genótipos de trigo estimada pela viabilidade polínica.
Objetivou-se estimar a estabilidade genética de 170 genótipos de trigo por meio da viabilidade polínica. Os genótipos foram provenientes do Banco Ativo de Germoplasma e dos ensaios de Valor e Cultivo e Uso da Embrapa Trigo, no período 2011 a 2013. Foram coletadas espigas em pré-antese, fixadas em Carnoy 3:1 e armazenadas em álcool 70%. As lâminas citológicas foram preparadas pela técnica de ?Squash? e corante carmin acético 1%. As análises foram em microscopia ótica, com três repetições e 1500 células/genótipo. Os resultados indicaram que 98% dos genótipos apresentaram viabilidade polínica acima de 95%, identificados como estáveis. Quanto às anormalidades, foram observados grãos de pólens vazios na maioria dos genótipos, mas com incidência muito baixas, não significativas
Telemonitoring in Chronic Obstructive Pulmonary Disease (CHROMED). A Randomized Clinical Trial
Rationale: Early detection of COPD exacerbations using tele-monitoring of physiological variables might reduce the frequency of hospitalisation. Objectives: To evaluate the efficacy of home monitoring of lung mechanics by the forced oscillation technique (FOT) and cardiac parameters in older COPD patients with co-morbidities.
Methods: This multicentre, randomized clinical trial recruited 312 GOLD grade II-IV COPD patients (median age 71 years [IQR:66-76], 49.6% grade II, 50.4% grade III-IV), with a history of exacerbation in the previous year and at least one non-pulmonary co-morbidity. Patients were randomised to usual care (n=158) or tele-monitoring (n=154) and followed for 9 months. All tele-monitoring patients self-assessed lung mechanics daily and in a subgroup with congestive heart failure (n=37) cardiac parameters were also monitored. An algorithm identified deterioration, triggering a telephone contact to determine appropriate interventions.
Measurements and Main results: Primary outcomes were time to first hospitalisation (TTFH) and change in EQ-5D utility index score. Secondary outcomes included: rate of antibiotic/corticosteroid prescriptions, hospitalisation, CAT, PHQ-9 and MLHF questionnaire scores, quality-adjusted life years and healthcare costs. Tele-monitoring did not affect TTFH, EQ-5D utility index score, antibiotic prescriptions, hospitalization rate and questionnaire scores. In an exploratory analysis, tele-medicine was associated with fewer repeat hospitalizations (-54%, p=0.017).
Conclusions: In older COPD patients with co-morbidities remote monitoring of lung function by FOT and cardiac parameters did not change TTFH and EQ-5D.
Clinical trial registration available at www.clinicaltrials.gov, ID NCT01960907
On cycle transversals and their connected variants in the absence of a small linear forest.
A graph is H-free if it contains no induced subgraph isomorphic to H. We prove new complexity results for the two classical cycle transversal problems Feedback Vertex Set and Odd Cycle Transversal by showing that they can be solved in polynomial time for (sP1+P3) -free graphs for every integer s≥1 . We show the same result for the variants Connected Feedback Vertex Set and Connected Odd Cycle Transversal. For the latter two problems we also prove that they are polynomial-time solvable for cographs; this was known already for Feedback Vertex Set and Odd Cycle Transversal
Estabilidade genética em genótipos de trigo estimada pela viabilidade polínica.
Objetivou-se estimar a estabilidade genética de 170 genótipos de trigo por meio da viabilidade polínica. Os genótipos foram provenientes do Banco Ativo de Germoplasma e dos ensaios de Valor e Cultivo e Uso da Embrapa Trigo, no período 2011 a 2013. Foram coletadas espigas em pré-antese, fixadas em Carnoy 3:1 e armazenadas em álcool 70%. As lâminas citológicas foram preparadas pela técnica de ?Squash? e corante carmin acético 1%. As análises foram em microscopia ótica, com três repetições e 1500 células/genótipo. Os resultados indicaram que 98% dos genótipos apresentaram viabilidade polínica acima de 95%, identificados como estáveis. Quanto às anormalidades, foram observados grãos de pólens vazios na maioria dos genótipos, mas com incidência muito baixas, não significativas
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