426 research outputs found
Optimal Design of an Inductive MHD Electric Generator
In this paper, the problem of optimizing the design of an inductive Magneto-Hydro-Dynamic (MHD) electric generator is formalized as a multi-objective optimization problem where the conflicting objectives consist of maximizing the output power while minimizing the hydraulic losses and the mass of the apparatus. In the proposal, the working fluid is ionized with periodical pulsed discharges and the resulting neutral plasma is unbalanced by means of an intense DC electrical field. The gas is thus split into two charged streams, which induce an electromotive force into a magnetically coupled coil. The resulting generator layout does not require the use of superconducting coils and allows you to manage the issues related to the conductivity of the gas and the corrosion of the electrodes, which are typical limits of the MHD generators. A tailored multi-objective optimization algorithm, based on the Tabu Search meta-heuristics, has been implemented, which returns a set of Pareto optimal solutions from which it is possible to choose the optimal solution according to further applicative or performance constraints
Optimization of a power line communication system to manage electric vehicle charging stations in a smart grid
In this paper, a procedure is proposed to design a power line communication (PLC) system to perform the digital transmission in a distributed energy storage system consisting of fleets of electric cars. PLC uses existing power cables or wires as data communication multicarrier channels. For each vehicle, the information to be transmitted can be, for example: the models of the batteries, the level of the charge state, and the schedule of charging/discharging. Orthogonal frequency division multiplexing modulation (OFDM) is used for the bit loading, whose parameters are optimized to find the best compromise between the communication conflicting objectives of minimizing the signal power, maximizing the bit rate, and minimizing the bit error rate. The off-line design is modeled as a multi-objective optimization problem, whose solution supplies a set of Pareto optimal solutions. At the same time, as many charging stations share part of the transmission line, the optimization problem includes also the assignment of the sub-carriers to the single charging stations. Each connection between the control node and a charging station has its own frequency response and is affected by a noise spectrum. In this paper, a procedure is presented, called Chimera, which allows one to solve the multi-objective optimization problem with respect to a unique frequency response, representing the whole set of lines connecting each charging station with the central node. Among the provided Pareto solutions, the designer will make the final decision based on the control system requirements and/or the hardware constraints
Crime scene and body alterations caused by arthropods: implications in death investigation
The activity of arthropods on corpses has been largely investigated, since they can produce information to reconstruct the peri-mortem events. However, the feeding/movement activity of insects around the crime scene, among the clothes and on the body, can also cause some alterations that can lead to wrong reconstruction and misinterpretations. This article summarises all the post-mortem arthropods artefacts related to the scene (i.e. fly artefacts and floor stripes) and the body (i.e. skin and other soft tissue alterations, bone alterations and hair alterations) that can mislead the forensic pathologist, discussing macroscopic and microscopic findings derived from forensic casework and from experimental laboratory studies, in order to provide a useful instrument to avoid misinterpretations and evaluation errors. Finally, some procedural notes for the documentation and the interpretation of findings are proposed
COVID-19: The wrong target for healthcare liability claims
Regrettably, after a first moment of appreciation and praise of the citizens for healthcare personnel facing COVID 19 pandemia, numerous episodes of actions taken against them on the issue of their legal liability followed. Impelling is to start an argumentation on this problem that aims to establish a shared conduct in dealing with them. The authors propose a basis for discussion on which to begin a constructive debate
Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests
INTRODUCTION: Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement. We assessed coronary microcirculation status by combining two functional tests in SSc patients and estimating its impact on disease outcome.
METHODS: Forty-one SSc patients, asymptomatic for coronary artery disease, were tested for coronary flow velocity reserve (CFR) by transthoracic-echo-Doppler with adenosine infusion (A-TTE) and for left ventricular wall motion abnormalities (WMA) by dobutamine stress echocardiography (DSE). Myocardial multi-detector computed tomography (MDCT) enabled the presence of epicardial stenosis, which could interfere with the accuracy of the tests, to be excluded. Patient survival rate was assessed over a 6.7- ± 3.5-year follow-up.
RESULTS: Nineteen out of 41 (46%) SSc patients had a reduced CFR (≤2.5) and in 16/41 (39%) a WMA was observed during DSE. Furthermore, 13/41 (32%) patients showed pathological CFR and WMA. An inverse correlation between wall motion score index (WMSI) during DSE and CFR value (r = -0.57, P <0.0001) was observed; in addition, CFR was significantly reduced (2.21 ± 0.38) in patients with WMA as compared to those without (2.94 ± 0.60) (P <0.0001). In 12 patients with abnormal DSE, MDCT was used to exclude macrovasculopathy. During a 6.7- ± 3.5-year follow-up seven patients with abnormal coronary functional tests died of disease-related causes, compared to only one patient with normal tests.
CONCLUSIONS: A-TTE and DSE tests are useful tools to detect non-invasively pre-clinical microcirculation abnormalities in SSc patients; moreover, abnormal CFR and WMA might be related to a worse disease outcome suggesting a prognostic value of these tests, similar to other myocardial diseases
Volumetric analysis of carotid plaque components and cerebral microbleeds: a correlative study
PURPOSE: The purpose of this work was to explore the association between carotid plaque volume (total and the subcomponents) and cerebral microbleeds (CMBs). MATERIALS AND METHODS: Seventy-two consecutive (male 53; median age 64) patients were retrospectively analyzed. Carotid arteries were studied by using a 16-detector-row computed tomography scanner whereas brain was explored with a 1.5 Tesla system. CMBs were studied using a T2*-weighted gradient-recalled echo sequence. CMBs were classified as from absent (grade 1) to severe (grade 4). Component types of the carotid plaque were defined according to the following Hounsfield unit (HU) ranges: lipid less than 60 HU; fibrous tissue from 60 to 130 HU; calcification greater than 130 HU, and plaque volumes of each component were calculated. Each carotid artery was analyzed by 2 observers. RESULTS: The prevalence of CMBs was 35.3%. A statistically significant difference was observed between symptomatic (40%) and asymptomatic (11%) patients (P value = .001; OR = 6.07). Linear regression analysis demonstrated an association between the number of CMBs and the symptoms (P = .0018). Receiver operating characteristics curve analysis found an association between the carotid plaque subcomponents and CMBs (Az = .608, .621, and .615 for calcified, lipid, and mixed components, respectively), and Mann-Whitney test confirmed this association in particular for the lipid components (P value = .0267). CONCLUSIONS: Results of this study confirm the association between CMBs and symptoms and that there is an increased number of CMBs in symptomatic patients. Moreover, we found that an increased volume of the fatty component is associated with the presence and number of CMBs
A real time bolometer tomographic reconstruction algorithm in nuclear fusion reactors
In tokamak nuclear fusion reactors, one of the main issues is to know the total emission of radiation, which is mandatory to understand the plasma physics and is very useful to monitor and control the plasma evolution. This radiation can be measured by means of a bolometer system that consists in a certain number of elements sensitive to the integral of the radiation along straight lines crossing the plasma. By placing the sensors in such a way to have families of crossing lines, sophisticated tomographic inversion algorithms allow to reconstruct the radiation tomography in the 2D poloidal cross-section of the plasma. In tokamaks, the number of projection cameras is often quite limited resulting in an inversion mathematic problem very ill conditioned so that, usually, it is solved by means of a grid-based, iterative constrained optimization procedure, whose convergence time is not suitable for the real time requirements. In this paper, to illustrate the method, an assumption not valid in general is made on the correlation among the grid elements, based on the statistical distribution of the radiation emissivity over a set of tomographic reconstructions, performed off-line. Then, a regularization procedure is carried out, which merge highly correlated grid elements providing a squared coefficients matrix with an enough low condition number. This matrix, which is inverted offline once for all, can be multiplied by the actual bolometer measures returning the tomographic reconstruction, with calculations suitable for real time application. The proposed algorithm is applied, in this paper, to a synthetic case study
CT attenuation analysis of carotid intraplaque hemorrhage
Background and Purpose: Intraplaque hemorrhage is considered a leading parameter of carotid plaque vulnerability. Our purpose was to assess the CT characteristics of intraplaque hemorrhage with histopathologic correlation to identify features that allow for confirming or ruling out the intraplaque hemorrhage. MATERIALS AND METHODS: This retrospective study included 91 patients (67 men; median age, 657 years; age range, 41-83 years) who underwent CT angiography and carotid endarterectomy from March 2010 to May 2013. Histopathologic analysis was performed for the tissue characterization and identification of intraplaque hemorrhage. Two observers assessed the plaque's attenuation values by using an ROI (≤1 and ≥2 mm2). Receiver operating characteristic curve, Mann-Whitney, and Wilcoxon analyses were performed. RESULTS: A total of 169 slices were assessed (59 intraplaque hemorrhage, 63 lipid-rich necrotic core, and 47 fibrous); the average values of the intraplaque hemorrhage, lipid-rich necrotic core, and fibrous tissue were 17.475 Hounsfield units (HU) and 18.407 HU, 39.476 HU and 48.048 HU, and 91.66 HU and 93.128 HU, respectively, before and after the administration of contrast medium. The Mann-Whitney test showed a statistically significant difference of HU values both in basal and after the administration of contrast material phase. Receiver operating characteristic analysis showed a statistical association between intraplaque hemorrhage and low HU values, and a threshold of 25 HU demonstrated the presence of intraplaque hemorrhage with a sensitivity and specificity of 93.22% and 92.73%, respectively. The Wilcoxon test showed that the attenuation of the plaque before and after administration of contrast material is different (intraplaque hemorrhage, lipid-rich necrotic core, and fibrous tissue had P values of .006, .0001, and .018, respectively). CONCLUSIONS: The results of this preliminary study suggest that CT can be used to identify the presence of intraplaque hemorrhage according to the attenuation. A threshold of 25 HU in the volume acquired after the administration of contrast medium is associated with an optimal sensitivity and specificity. Special care should be given to the correct identification of the ROI
Computational Fluid Dynamics Simulations of an Innovative System of Wind Power Generation
Abstract: In this work an innovative system for wind power generation in urban areas is proposed. The generation system substitutes the roof of the building and it consists of a static part, the stator, and a moving part, called impeller or rotor, which is a centripetal turbine with vertical axis of rotation. The rotary motion of the rotor is transferred through a shaft to a generator that produces electricity. Since the objective is to conveying the air flow in the stator in order to avoid the formation of vortices, the logarithmic spiral has been chosen as the shape for the stator blades. A 2D and a 3D model of the system are analyzed in order to evaluate the efficiency of the new system proposed considering both the influence of the profile of the building and the effect of impedance of the duct on the available power to the impeller
- …