3 research outputs found
Heterofucans from Dictyota menstrualis have anticoagulant activity
- Author
- Publication venue
- Associação Brasileira de Divulgação Científica
- Publication date
- 01/02/2004
- Field of study
Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins. Plant fucans have several biological activities, including anticoagulant and antithrombotic, related to the structural and chemical composition of polysaccharides. We have extracted sulfated polysaccharides from the brown seaweed Dictyota menstrualis by proteolytic digestion, followed by separation into 5 fractions by sequential acetone precipitation. Gel electrophoresis using 0.05 M 1,3-diaminopropane-acetate buffer, pH 9.0, stained with 0.1% toluidine blue, showed the presence of sulfated polysaccharides in all fractions. The chemical analyses demonstrated that all fractions are composed mainly of fucose, xylose, galactose, uronic acid, and sulfate. The anticoagulant activity of these heterofucans was determined by activated partial thromboplastin time (APTT) using citrate normal human plasma. Only the fucans F1.0v and F1.5v showed anticoagulant activity. To prolong the coagulation time to double the baseline value in the APTT, the required concentration of fucan F1.0v (20 µg/ml) was only 4.88-fold higher than that of the low molecular weight heparin Clexane® (4.1 µg/ml), whereas 80 µg/ml fucan 1.5 was needed to obtain the same effect. For both fucans this effect was abolished by desulfation. These polymers are composed of fucose, xylose, uronic acid, galactose, and sulfate at molar ratios of 1.0:0.8:0.7:0.8:0.4 and 1.0:0.3:0.4:1.5:1.3, respectively. This is the fist report indicating the presence of a heterofucan with higher anticoagulant activity from brown seaweed
Subcutaneous hydration and medications infusions (effectiveness, safety, acceptability): A systematic review of systematic reviews
- Author
- A Al Nofal
- A Frisoli
- AL Bredlau
- BJ Shea
- Brenda Gray
- C Fonzo-Christe
- C Hallam
- C Jayr
- D Marikar
- D McGowan
- D Moher
- D Moriarty
- Daphne Broadhurst
- Deepa Sriram
- E Alexandrou
- E Aromataris
- E Bruera
- E Bruera
- E Bruera
- E Kalso
- E. Colin
- G Slesak
- H Abolhassani
- H Barnes
- I Furtado
- J Lingman-Framme
- J Pershad
- JB Santolucito
- JK Luk
- José das Neves
- JP Reichmann
- K Ker
- K Macmillan
- KL Stoner
- KR Carlson
- L Cerchietti
- L Forbat
- LA Gorski
- LM Gaudet
- M Dasgupta
- M Schmidt‐Hansen
- Marie Cooke
- MB Danielsen
- MC Torre
- MJ Cabañero-Martínez
- ML Hawes
- MMD Vidal
- N Pouvreau
- NL Moureau
- NRN Moureau
- NS Gomes
- NS Paramothayan
- O Duems Noriega
- O Duems-Noriega
- P Good
- PA Rochon
- PM Fortin
- PR Spandorfer
- R Caccialanza
- R Perry
- R Remington
- RFF Bell
- RL Fainsinger
- RW Orrell
- S O’Keeffe
- S Rouhani
- SA Fisher
- SEMD Mace
- SL Anderson
- SS Dychter
- T Turner
- V Chopra
- V Dardaine
- YC Challiner
- Z Arinzon
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Performance of reconstruction and identification of tau leptons decaying to hadrons and nu(tau) in pp collisions at root s=13 TeV
- Author
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- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WW
- Abdullin S
- Abdulsalam A
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- Adzic P
- Afanasiev S
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- Lustermann W
- Luukka P
- Luyando JG
- Lychkovskaya N
- Lykken J
- Lyons L
- Ma P
- MacDonald E
- Mackay C
- Madlener T
- Madrid C
- Maeshima K
- Maestre JA
- Maggi G
- Maggi M
- Magitteri A
- Magnan A
- Magnani A
- Mahrous A
- Maier B
- Maity M
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- Majumder D
- Majumder G
- Makovec A
- Maksimovic P
- Mal P
- Malakhov A
- Malberti M
- Malbouisson H
- Malcles J
- Malgeri L
- Malhotra S
- Malik S
- Mallios S
- Malvezzi S
- Mamouni HE
- Manca E
- Mandal K
- Mandorli G
- Mandrik P
- Manganote ET
- Mankel R
- Mannelli M
- Manoni E
- Mans J
- Manteca PF
- Manthos N
- Mantovani G
- Manzano PDC
- Manzoni R
- Mao Y
- Mao Z
- Maravin Y
- Marcellini S
- Marchesini I
- Marco ED
- Marco J
- Marconi D
- Margoni M
- Maria RD
- Mariani V
- Marini A
- Marinov A
- Marionneau M
- Mariotti C
- Marono MV
- Marraffino J
- Martelli A
- Martin MA
- Martinez G
- Martins CDO
- Martínez AB
- Marzocchi B
- Masciovecchio M
- Maselli S
- Masetti G
- Mason D
- Massironi A
- Mastrolorenzo L
- Matchev K
- Matorras F
- Mattia AD
- Matveev V
- Mavromanolakis G
- Mazumdar K
- Mcbrayer W
- McBride P
- Mccoll N
- Mcdermott K
- Mcginn C
- Mcmaster B
- Mechelen PV
- Mehta A
- Mei H
- Meijers F
- Meinhard M
- Melzer-Pellmann I
- Menasce D
- Mendis D
- Meneguzzo A
- Menendez JF
- Menichelli M
- Meo SL
- Meola S
- Mercadante P
- Meridiani P
- Merkel P
- Merlin J
- Merlo J
- Merschmeyer M
- Mersi S
- Mertens A
- Meschi E
- Meschini M
- Mesic B
- Messineo A
- Mestvirishvili A
- Meyer A
- Meyer M
- Miagkov I
- Micheli F
- Migliore E
- Mignerey A
- Mikulec I
- Mildner H
- Milenovic P
- Millet P
- Mills C
- Milosevic J
- Miniello G
- Mirabito L
- Mirman N
- Mironov C
- Misheva M
- Misiura M
- Missiroli M
- Mitchell T
- Mitra S
- Mitselmakher G
- Mittag G
- Mnich J
- Modak A
- Moeller A
- Mohamed A
- Mohammadi A
- Mohanty G
- Moisenz P
- Molnar J
- Monaco V
- Mondal K
- Montagna P
- Montanari A
- Monteil E
- Monteno M
- Monti F
- Montoya CC
- Moon C
- Moon D
- Moortgat F
- Moortgat S
- Morabit KE
- Moraes A
- Moran D
- Moreels L
- Moreno SC
- Moroni L
- Morton A
- Mossolov V
- Mousa J
- Mozer M
- Mrenna S
- Mudholkar T
- Mukherjee S
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- Mulders PV
- Mulhearn M
- Mulholland T
- Multhaup J
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- Murzin V
- Musella P
- Musich M
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- Myronenko V
- Mäenpää T
- Müller T
- Nachtman J
- Nagy M
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- Nam K
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- Narayanan S
- Naseri M
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- Navarria F
- Nawrocki K
- Nayak A
- Negra MD
- Negrete MO
- Negro G
- Nehrkorn A
- Nemallapudi M
- Nessi-Tedaldi F
- Netrakanti P
- Neutelings I
- Newbold D
- Newman H
- Ngadiuba J
- Nguyen M
- Nguyen T
- Nicolaou C
- Niedziela M
- Niemeyer C
- Nikitenko A
- Niu X
- Nogima H
- Noonan D
- Nourbakhsh S
- Novaes S
- Nowack A
- Nowatschin D
- Nuzzo S
- O'Dell V
- Obertino M
- Obraztsov S
- Ochando C
- Oglakci M
- Ogul H
- Oh G
- Oh S
- Oh Y
- Okhotnikov V
- Olaiya E
- Oliveira ACAD
- Oliveros S
- Olivito D
- Olsson MV
- Olszewski M
- Onel Y
- Onengut G
- Onsem GV
- Oreshkin V
- Orfanelli S
- Organtini G
- Orsini L
- Ortona G
- Ovcharova A
- Ozdemir K
- Ozkorucuklu S
- Ozok F
- Ozturk S
- Pacher L
- Padhi S
- Padula S
- Paganini P
- Paganis E
- Paganoni M
- Palichik V
- Palla F
- Palladino V
- Palma MD
- Panagiotou A
- Pandey S
- Pandolfi F
- Paneva M
- Pant L
- Pantaleo F
- Paoletti S
- Paolucci P
- Papadopoulos I
- Papakrivopoulos I
- Papavergou I
- Pape L
- Paradas E
- Paramatti R
- Paramesvaran S
- Pardos CD
- Parijs IV
- Park I
- Park S
- Parygin P
- Pashenkov A
- Paspalaki G
- Passaseo M
- Pastika N
- Pastrone N
- Pasztor G
- Pata J
- Patel R
- Patterson J
- Paulini M
- Paus C
- Pauss F
- Pavlov B
- Pazzini J
- Pedraza I
- Pedrini D
- Pedro K
- Pekkanen J
- Pelayo JP
- Pellett D
- Pelliccioni M
- Pena C
- Penning B
- Penzo A
- Pereira AV
- Perelygin V
- Perez E
- Perieanu A
- Peris AD
- Perries S
- Perrin G
- Perrotta A
- Perrozzi L
- Perry T
- Peruzzi M
- Pesaresi M
- Petkov P
- Petrilli A
- Petrov V
- Petrucciani G
- Petrushanko S
- Petyt D
- Pfeiffer A
- Pflitsch S
- Philippov D
- Piccolo D
- Pieri M
- Pierini M
- Pieters M
- Pigard P
- Pigazzini S
- Pilot J
- Pineda AM
- Pinna D
- Piotrzkowski K
- Pistone C
- Pitters F
- Pitzl D
- Plagge M
- Pol M
- Polikarpov S
- Pompili A
- Pook T
- Pooth O
- Popov A
- Popov V
- Popova E
- Porta GZD
- Postiau N
- Potenza R
- Poyraz D
- Pozdnyakov A
- Pozdnyakov I
- Pozzobon N
- Preiato F
- Preuten M
- Prieels C
- Primavera F
- Priyanka P
- Prokofyev O
- Prosper H
- Psallidas A
- Ptochos F
- Pugliese G
- Puljak I
- Purohit A
- Pyskir A
- Python Q
- Qian S
- Qu H
- Quach D
- Quast G
- Quero BC
- Quijada JM
- Quittnat M
- Rabadan-Trejo R
- Rabady D
- Rabbertz K
- Racz A
- Rad N
- Radburn-Smith B
- Radogna R
- Radziej M
- Ragazzi S
- Rahatlou S
- Rahmani M
- Raics P
- Raidal M
- Rakness G
- Ramirez-Garcia M
- Ramirez-Sanchez G
- Ramos JF
- Rander J
- Rane A
- Ranieri A
- Ranjan K
- Rankin D
- Raspereza A
- Ratti S
- Rauch M
- Rauco G
- Ravera F
- Razis P
- Re DD
- Re V
- Rebassoo F
- Redondo I
- Regnard S
- Reid I
- Reimers A
- Reis T
- Reithler H
- Rembser J
- Remortel NV
- Ressegotti M
- Reyes-Almanza R
- Ricca GD
- Riccardi C
- Ricci-Tam F
- Richards A
- Richardson C
- Richman J
- Rieger M
- Rieger O
- Rinkevicius A
- Ristori L
- Rivero CM
- Rizzi A
- Robmann P
- Robutti E
- Rodozov M
- Rodrigo T
- Roeck AD
- Rogan C
- Roh Y
- Rohe T
- Rohlf J
- Rohringer H
- Roland C
- Roland G
- Rolandi G
- Rold AD
- Romeo F
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- Romero L
- Ronchese P
- Rosas LS
- Rose A
- Rosenzweig D
- Roskas C
- Roskes J
- Rosowsky A
- Rossi A
- Rossin R
- Rout P
- Rovelli C
- Rovelli T
- Rovere M
- Roy A
- Roy D
- Roy T
- Ruckstuhl N
- Ruini D
- Ruiz-Jimeno A
- Rumerio P
- Rusack R
- Rusakov S
- Rusinov V
- Ruspa M
- Russo L
- Ryd A
- Rykaczewski H
- Ryutin R
- Sacchi R
- Saddique A
- Safarzadeh B
- Safronov G
- Saggio A
- Sagir S
- Saha A
- Saha G
- Sahin M
- Sahoo D
- Sahoo N
- Saini L
- Sakulin H
- Sakuma T
- Salama E
- Salerno D
- Salerno R
- Saltzberg D
- Salvini P
- Sanchez MCDLB
- Sanchez-Hernandez A
- Sandeep K
- Sanders S
- Sani M
- Santanastasio F
- Santocchia A
- Santoro A
- Saoulidou N
- Sarica U
- Sarkar S
- Sarkar T
- Sauvan J
- Savitskyi M
- Savoy-Navarro A
- Savrin V
- Saxena P
- Scharf C
- Schiber C
- Schieck J
- Schleper P
- Schmidt A
- Schmitz E
- Schnaible C
- Schneider B
- Schomakers C
- Schröder M
- Schulz J
- Schumann S
- Schwandt J
- Schwanenberger C
- Schweiger K
- Schwick C
- Schäfer C
- Schöfbeck R
- Schönenberger M
- Schütze P
- Sciacca C
- Scodellaro L
- Scott E
- Sculac T
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- Seidel M
- Seitz C
- Seixas J
- Sekmen S
- Selvaggi G
- Selvaggi M
- Sen S
- Seo S
- Sert H
- Sevilla MF
- Sexton-Kennedy E
- Sguazzoni G
- Shah A
- Shah M
- Shaheen S
- Shalhout S
- Sharan M
- Sharma A
- Sharma R
- Sharma S
- Sharma V
- Shchelina K
- Shchutska L
- Shepherd-Themistocleous C
- Shevchenko R
- Shi K
- Shi M
- Shin Y
- Shirazi SG
- Shmatov S
- Shoaib M
- Shopova M
- Shtipliyski A
- Shukla P
- Shulha S
- Shvetsov I
- Si W
- Sieber G
- Sierra LC
- Siikonen H
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- Silva GC
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- Silva WPD
- Silveira GD
- Silvestris L
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- Simonetto F
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- Sirois Y
- Siroli G
- Sirunyan A
- Skatchkov N
- Skhirtladze N
- Skinnari L
- Skovpen K
- Skovpen Y
- Skuja A
- Slabospitskii S
- Smirnov I
- Smirnov V
- Smith C
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- Sobol A
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- Sola V
- Solano A
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- Sonneveld J
- Sordini V
- Sosnov D
- Souza SFD
- Spagnolo P
- Spalding W
- Spanring M
- Sperka D
- Sphicas P
- Spiegel L
- Spiezia A
- Spiga D
- Spiridonov A
- Spiropulu M
- Spitzbart D
- Srimanobhas N
- Stadie H
- Stahl A
- Staiano A
- Stakia A
- Starling E
- Starodumov A
- Steen A
- Steggemann J
- Steinbrück G
- Stenson K
- Stepennov A
- Stephans G
- Stober F
- Stolin V
- Stolp D
- Stoye M
- Stoynev S
- Strait J
- Strebler T
- Strobbe N
- Strologas J
- Strom D
- Strong G
- Stuart D
- Stöver M
- Suarez I
- Sulak L
- Sulimov V
- Sultanov G
- Summers S
- Sumorok K
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- Surányi O
- Susa T
- Sutar B
- Suwonjandee N
- Swain S
- Swartz M
- Syarif R
- Szillasi Z
- Szleper M
- Sznajder A
- Tadavani EE
- Tadel M
- Takahashi Y
- Takaki JT
- Tali B
- Tan S
- Tao J
- Tao Z
- Tapper A
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- Taurok A
- Tavernier S
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- Teles PR
- Tenchini R
- Teodorescu L
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- Teroerde M
- Teyssier D
- Thakur S
- Thea A
- Theofilatos K
- Thiel M
- Tholen H
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- Thomas L
- Tiko A
- Tiras E
- Titov M
- Titterton A
- Tiwari P
- Tkaczyk S
- Tlisov D
- Tok U
- Toldaiev O
- Tomalin I
- Tomei TFP
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- Tonjes M
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- Topaksu AK
- Topsis-Giotis I
- Torassa E
- Toriashvili T
- Toropin A
- Tos K
- Tosi M
- Tosi N
- Tosi S
- Touquet G
- Traczyk P
- Tran N
- Treille D
- Trevisani N
- Triantis F
- Tricomi A
- Triossi A
- Tripathi M
- Trocino D
- Trocsanyi Z
- Troshin S
- Tsamalaidze Z
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- Tsirou A
- Tsitsonis D
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- Tumasyan A
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- Tyurin N
- Tziaferi E
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- Ujvari B
- Ulmer K
- Ulrich R
- Uplegger L
- Usai E
- Uvarov L
- Uzunian A
- Vaandering E
- Vadruccio D
- Vagnerini A
- Vai I
- Vaitkus J
- Valencia FV
- Valle AED
- Valuev V
- Vanhoefer A
- Vanlaer P
- Vannerom D
- Varela J
- Varelas N
- Vartak A
- Vavilov S
- Vazzoler F
- Veckalns V
- Veelken C
- Velde CV
- Velicanu D
- Vellidis K
- Venditti R
- Venturi A
- Verbeke W
- Verdini P
- Veres G
- Vermassen B
- Vernieri C
- Verwilligen P
- Verzetti M
- Verzocchi M
- Veszpremi V
- Vesztergombi G
- Vidal R
- Vila I
- Viliani L
- Virdee T
- Virdi A
- Viret S
- Virto AL
- Vischia P
- Vit M
- Vitulo P
- Vlasov E
- Vlimant J
- Voevodina E
- Volkov A
- Vormwald B
- Vorobiev I
- Vorobyev A
- Voutilainen M
- Voytishin N
- Vámi T
- Wadud M
- Wagner S
- Walczak M
- Walia G
- Wallny R
- Walsh R
- Waltenberger W
- Wang D
- Wang H
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- Wang L
- Wang M
- Wang Q
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- Wang T
- Wang X
- Wang Y
- Wang Z
- Waqas M
- Wardle N
- Wasserbaech S
- Wayand S
- Weber H
- Weber M
- Wei H
- Weiler T
- Weinberg M
- Wen Y
- Wertz S
- West C
- Wetzel J
- Whitbeck A
- Wichmann K
- Wickramage N
- Wiederkehr S
- Wilkinson R
- Williams T
- Williamson S
- Wimpenny S
- Winterbottom D
- Wissing C
- Wit AD
- Wittich P
- Wittmann J
- Wittmer B
- Wolf ED
- Wolf R
- Womersley W
- Wong K
- Wood J
- Wright D
- Wright J
- Wu Z
- Wulz C
- Wyslouch B
- Wöhrmann C
- Würthwein F
- Xiao M
- Xie S
- Xu Z
- Yagil A
- Yalvac M
- Yang U
- Yang Y
- Yates B
- Yazgan E
- Yetkin E
- Yohay R
- Yoo H
- Yoo J
- You C
- Yu D
- Yu G
- Yu I
- Yu S
- Yuan L
- Yumiceva F
- Yusli M
- Yzquierdo AP
- Zabi A
- Zaganidis N
- Zahid S
- Zalewski P
- Zanetti A
- Zanetti M
- Zarubin A
- Zarucki M
- Zeid SA
- Zeinali M
- Zenaiev O
- Zenz S
- Zeuner W
- Zeyrek M
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhang S
- Zhang Z
- Zhao J
- Zhaozhong S
- Zhokin A
- Zhu D
- Zhu R
- Zhukov V
- Zientek M
- Zito G
- Zobec J
- Zoi I
- Zolkapli Z
- Zorbakir I
- Zorbilmez C
- Zotto P
- Zou D
- Zucchetta A
- Zuolo D
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2018
- Field of study