Probabilistic Motion Modeling from Medical Image Sequences: Application to Cardiac Cine-MRI

Probabilistic Motion Model, Motion Tracking, Temporal Super-Resolution, Diffeomorphic Registration, Temporal Variational AutoencoderInternational audienceWe propose to learn a probabilistic motion model from a sequence of images. Besides spatio-temporal registration, our method offers to predict motion from a limited number of frames, useful for temporal super-resolution. The model is based on a probabilistic latent space and a novel temporal dropout training scheme. This enables simulation and interpolation of realistic motion patterns given only one or any subset of frames of a sequence. The encoded motion also allows to be transported from one subject to another without the need of inter-subject registration. An unsupervised generative deformation model is applied within a temporal convolutional network which leads to a diffeomorphic motion model, encoded as a low-dimensional motion matrix. Applied to cardiac cine-MRI sequences, we show improved registration accuracy and spatio-temporally smoother deformations compared to three state-of-the-art registration algorithms. Besides, we demonstrate the model's applicability to motion transport by simulating a pathology in a healthy case. Furthermore, we show an improved motion reconstruction from incomplete sequences compared to linear and cubic interpolation

Multimodal image alignment through a multiscale chain of neural networks with application to remote sensing

International audienceWe tackle here the problem of multimodal image non-rigid registration, which is of prime importance in remote sensing and medical imaging. The difficulties encountered by classical registration approaches include feature design and slow optimization by gradient descent. By analyzing these methods, we note the significance of the notion of scale. We design easy-to-train, fully-convolutional neural networks able to learn scale-specific features. Once chained appropriately, they perform global registration in linear time, getting rid of gradient descent schemes by predicting directly the deformation. We show their performance in terms of quality and speed through various tasks of remote sensing multimodal image alignment. In particular, we are able to register correctly cadastral maps of buildings as well as road polylines onto RGB images, and outperform current keypoint matching methods