958 research outputs found

    Simple bounds for one-shot pure-state distillation in general resource theories

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    Β© 2020 American Physical Society. We present bounds for distilling many copies of a pure state from an arbitrary initial state in a general quantum resource theory. Our bounds apply to operations that are able to generate no more than a Ξ΄ amount of resource, where Ξ΄β‰₯0 is a given parameter. To maximize applicability of our upper bound, we assume little structure on the set of free states under consideration besides a weak form of superadditivity of the function Gmin(ρ), which measures the overlap between ρ and the set of free states. Our bounds are given in terms of this function and the robustness of resource. Known results in coherence and entanglement theory are reproduced in this more general framework

    Hierarchy of quantum operations in manipulating coherence and entanglement

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    Quantum resource theory under different classes of quantum operations advances multiperspective understandings of inherent quantum-mechanical properties, such as quantum coherence and quantum entanglement. We establish hierarchies of different operations for manipulating coherence and entanglement in distributed settings, where at least one of the two spatially separated parties are restricted from generating coherence. In these settings, we introduce new classes of operations and also characterize those maximal, i.e., the resource-non-generating operations, progressing beyond existing studies on incoherent versions of local operations and classical communication and those of separable operations. The maximal operations admit a semidefiniteprogramming formulation useful for numerical algorithms, whereas the existing operations not. To establish the hierarchies, we prove a sequence of inclusion relations among the operations by clarifying tasks where separation of the operations appears. We also demonstrate an asymptotically non-surviving separation of the operations in the hierarchy in terms of performance of the task of assisted coherence distillation, where a separation in a one-shot scenario vanishes in the asymptotic limit. Our results serve as fundamental analytical and numerical tools to investigate interplay between coherence and entanglement under different operations in the resource theory

    Hierarchy of quantum operations in manipulating coherence and entanglement

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    Quantum resource theory under different classes of quantum operations advances multiperspective understandings of inherent quantum-mechanical properties, such as quantum coherence and quantum entanglement. We establish hierarchies of different operations for manipulating coherence and entanglement in distributed settings, where at least one of the two spatially separated parties are restricted from generating coherence. In these settings, we introduce new classes of operations and also characterize those maximal, i.e., the resource-non-generating operations, progressing beyond existing studies on incoherent versions of local operations and classical communication and those of separable operations. The maximal operations admit a semidefinite-programming formulation useful for numerical algorithms, whereas the existing operations not. To establish the hierarchies, we prove a sequence of inclusion relations among the operations by clarifying tasks where separation of the operations appears. We also demonstrate an asymptotically non-surviving separation of the operations in the hierarchy in terms of performance of the task of assisted coherence distillation, where a separation in a one-shot scenario vanishes in the asymptotic limit. Our results serve as fundamental analytical and numerical tools to investigate interplay between coherence and entanglement under different operations in the resource theory

    Microdevices for extensional rheometry of low viscosity elastic liquids : a review

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    Extensional flows and the underlying stability/instability mechanisms are of extreme relevance to the efficient operation of inkjet printing, coating processes and drug delivery systems, as well as for the generation of micro droplets. The development of an extensional rheometer to characterize the extensional properties of low viscosity fluids has therefore stimulated great interest of researchers, particularly in the last decade. Microfluidics has proven to be an extraordinary working platform and different configurations of potential extensional microrheometers have been proposed. In this review, we present an overview of several successful designs, together with a critical assessment of their capabilities and limitations

    Genome wide analysis of gene expression changes in skin from patients with type 2 diabetes

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    Non-healing chronic ulcers are a serious complication of diabetes and are a major healthcare problem. While a host of treatments have been explored to heal or prevent these ulcers from forming, these treatments have not been found to be consistently effective in clinical trials. An understanding of the changes in gene expression in the skin of diabetic patients may provide insight into the processes and mechanisms that precede the formation of non-healing ulcers. In this study, we investigated genome wide changes in gene expression in skin between patients with type 2 diabetes and non-diabetic patients using next generation sequencing. We compared the gene expression in skin samples taken from 27 patients (13 with type 2 diabetes and 14 non-diabetic). This information may be useful in identifying the causal factors and potential therapeutic targets for the prevention and treatment of diabetic related diseases

    Role of the CCAAT-Binding Protein NFY in SCA17 Pathogenesis

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    Spinocerebellar ataxia 17 (SCA17) is caused by expansion of the polyglutamine (polyQ) tract in human TATA-box binding protein (TBP) that is ubiquitously expressed in both central nervous system and peripheral tissues. The spectrum of SCA17 clinical presentation is broad. The precise pathogenic mechanism in SCA17 remains unclear. Previously proteomics study using a cellular model of SCA17 has revealed reduced expression of heat shock 70 kDa protein 5 (HSPA5) and heat shock 70 kDa protein 8 (HSPA8), suggesting that impaired protein folding may contribute to the cell dysfunction of SCA17 (Lee et al., 2009). In lymphoblastoid cells, HSPA5 and HSPA8 expression levels in cells with mutant TBP were also significantly lower than that of the control cells (Chen et al., 2010). As nuclear transcription factor Y (NFY) has been reported to regulate HSPA5 transcription, we focused on if NFY activity and HSPA5 expression in SCA17 cells are altered. Here, we show that TBP interacts with NFY subunit A (NFYA) in HEK-293 cells and NFYA incorporated into mutant TBP aggregates. In both HEK-293 and SH-SY5Y cells expressing TBP/Q61∼79, the level of soluble NFYA was significantly reduced. In vitro binding assay revealed that the interaction between TBP and NFYA is direct. HSPA5 luciferase reporter assay and endogenous HSPA5 expression analysis in NFYA cDNA and siRNA transfection cells further clarified the important role of NFYA in regulating HSPA5 transcription. In SCA17 cells, HSPA5 promoter activity was activated as a compensatory response before aggregate formation. NFYA dysfunction was indicated in SCA17 cells as HSPA5 promoter activity reduced along with TBP aggregate formation. Because essential roles of HSPA5 in protection from neuronal apoptosis have been shown in a mouse model, NFYA could be a target of mutant TBP in SCA17

    Limits on WWZ and WW\gamma couplings from p\bar{p}\to e\nu jj X events at \sqrt{s} = 1.8 TeV

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    We present limits on anomalous WWZ and WW-gamma couplings from a search for WW and WZ production in p-bar p collisions at sqrt(s)=1.8 TeV. We use p-bar p -> e-nu jjX events recorded with the D0 detector at the Fermilab Tevatron Collider during the 1992-1995 run. The data sample corresponds to an integrated luminosity of 96.0+-5.1 pb^(-1). Assuming identical WWZ and WW-gamma coupling parameters, the 95% CL limits on the CP-conserving couplings are -0.33<lambda<0.36 (Delta-kappa=0) and -0.43<Delta-kappa<0.59 (lambda=0), for a form factor scale Lambda = 2.0 TeV. Limits based on other assumptions are also presented.Comment: 11 pages, 2 figures, 2 table

    Who needs bereavement support? A population based survey of bereavement risk and support need

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    This study identifies and describes the profiles of bereavement risk and support needs of a community sample in Australia and tests the fit of the data with the three-tiered public health model for bereavement support. Family members who were bereaved 6-24 months prior to the survey and who were clients of four funeral providers participated (May-July 2013). A postal survey was used to collect information about bereaved people's experience of caring and perceived satisfaction with any bereavement support provided. The questionnaire included a validated risk assessment screening measure for Prolonged Grief Disorder (PG-13). A total of 678 bereaved people responded. The model predicted that 60% of the sample would be low risk, 30% moderate risk, and 10% high risk. Actual figures were very close at 58.4%, 35.2%and 6.4% respectively. The analysis of the demographic characteristics, experience and impact of caring and bereavement, and satisfaction with support received from a variety of sources revealed differential experiences and needs that align with the expectation of low, moderate, and high bereavement support need, as articulated in the public health model. This is the first empirical test of the public health model of bereavement support. As there is a lack of clear evidence to guide development and allocation of bereavement support programs, the findings have the potential to inform the ability of services, community organizations and informal networks to prioritize care according to each level of bereavement need. This is essential to achieve cost-effective and equitable resource allocation

    Search For Heavy Pointlike Dirac Monopoles

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    We have searched for central production of a pair of photons with high transverse energies in ppΛ‰p\bar p collisions at s=1.8\sqrt{s} = 1.8 TeV using 70pbβˆ’170 pb^{-1} of data collected with the D\O detector at the Fermilab Tevatron in 1994--1996. If they exist, virtual heavy pointlike Dirac monopoles could rescatter pairs of nearly real photons into this final state via a box diagram. We observe no excess of events above background, and set lower 95% C.L. limits of 610,870,or1580GeV/c2610, 870, or 1580 GeV/c^2 on the mass of a spin 0, 1/2, or 1 Dirac monopole.Comment: 12 pages, 4 figure
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