62 research outputs found
A comparison of morphogenesis of muscles of the forearm and hand during ontogenesis and regeneration in the axolotl ( Ambystoma mexicanum )
The morphogenesis of muscles of the forearm and hand was studied in embryonic limbs of the axolotl ( Ambystoma mexicanum ) and compared with the course of morphogenesis in the regenerating limb of adults. The first part of the paper describes the morphogenesis of muscles ontogenetic development. The course of development, from the stage of muscle blastemas through that of the independent muscle anlagen is described for each muscle. The separation of muscle anlagen and their differentiation forms a prominent proximodistal gradient. At the same time there is a clear radioulnar gradient in the formation of muscle anlagen. Phylogenetically, this radioulnar gradient is restricted to the developing limb of Urodeles. In the second part of the paper, the morphogenesis of muscles is described in the regenerating limb. The major features in regeneration recapitulate those in the embryonic limb. Proximodistal and radioulnar gradients of development are also present in the regenerating limb. This structural similarity in development supports the viewpoint that the regeneration blastema is an integrated morphogenetic unit in which muscles differentiate according to the same genetic plan as they do in the embryo. There are some differences, however, between the regenerating and embryonic limb. The regenerating limb is larger, its muscle blastemas are also larger from the beginning, and the regenerating limb has a relatively greater amount of mesenchymal cells, which are not closely integrated into the muscle or skeletal anlagen.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47521/1/429_2004_Article_BF00519726.pd
Hand/foot splitting and the ‘re-evolution’ of mesopodial skeletal elements during the evolution and radiation of chameleons
Etude morphologique et cytochimique du developpement des membres chez la souris et chez la taupe.
Histochemical observations on the developing foot of normal, oligosyndactylous (os/&) and syndactylous (sm/sm) mouse embryos.
Detection histochimique de modifications des ebauches dans les membres en formation chez la souris oligosyndactyle.
Sites of Aspecific ATP-Phosphohydrolase Activity in the Branchial Region of Chick Embryos, with Particular Emphasis on the Myogenic Cell Population
Prevention of Genetic Polydactyly in Polydactyly Nagoya (Pdn) Mice in Vitro by Surgical Treatment of Foot Plate during Embryogenesis
- …