25 research outputs found

    Toleransi beragama dan harmonisasi sosial

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    Masyarakat Indonesia yang majemuk selalu dihadapkan pada permasalahan sosial berdasarkan pada kemajemukannya itu. Sayang sekali masih ada saja pihak-pihak yang lebih mementingkan golongannya daripada kepentingan publik. Untuk itu, selalu saja ada konflik sosial berdasarkan pada identitas golongan, terutama identitas agama. Padahal, masing-masing agama mempunyai ajaran tersendiri untuk hidup toleran dan berdampingan dengan penganut agama lain

    Supercritical fluid technology as a tool to prepare gradient multifunctional architectures towards regeneration of osteochondral injuries

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    Platelet lysates (PLs) are a natural source of growth factors (GFs) known for its stimulatory role on stem cells which can be obtained after activation of platelets from blood plasma. The possibility to use PLs as growth factor source for tissue healing and regeneration has been pursued following different strategies. Platelet lysates are an enriched pool of growth factors which can be used as either a GFs source or as a three-dimensional (3D) hydrogel. However, most of current PLs-based hydrogels lack stability, exhibiting significant shrinking behavior. This chapter focuses on the application of supercritical fluid technology to develop three-dimensional architectures of PL constructs, crosslinked with genipin. The proposed technology allows in a single step operation the development of mechanically stable porous structures, through chemical crosslinking of the growth factors present in the PL pool, followed by supercritical drying of the samples. Furthermore gradient structures of PL-based structures with bioactive glass are also presented and are described as an interesting approach to the treatment of osteochondral defects.info:eu-repo/semantics/publishedVersio

    Nature meets nurture: molecular genetics of gastric cancer

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    The immensity of genes and molecules implicated in gastric carcinogenesis is overwhelming and the relevant importance of some of these molecules is too often unclear. This review serves to bring us up-to-date with the latest findings as well as to look at the larger picture in terms of how to tackle the problem of solving this multi-piece puzzle. In this review, the environmental nurturing of intestinal cancer is discussed, beginning with epidemiology (known causative factors for inducing molecular change), an update of H. pylori research, including the role of inflammation and stem cells in premalignant lesions. The role of E-cadherin in the nature (genotype) of diffuse gastric cancer is highlighted, and finally the ever growing discipline of SNP analysis (including IL1B) is discussed

    Synthesis, Characterization and Surface Properties of Amidosulfobetaine Surfactants Bearing Odd-Number Hydrophobic Tail

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    Three amidosulfobetaine surfactants were synthesized namely: 3‐(N‐pentadecanamidopropyl‐N,N‐dimethyl ammonium) propanesulfonate (2a); 3‐(N‐heptadecanamidopropyl‐N,N‐dimethyl ammonium) propanesulfonate (2b), and 3‐(N‐nonadecanamidopropyl‐N,N‐dimethyl ammonium) propanesulfonate (2c). These surfactants were prepared by direct amidation of commercially available fatty acids with 3‐(dimethylamino)‐1‐propylamine and subsequent reaction with 1,3‐propanesultone to obtain quaternary ammonium salts. The synthesized surfactants were characterized by IR, NMR and mass spectrometry. Thermogravimetric analysis (TGA) results showed that the synthesized surfactants have excellent thermal stability with no major thermal degradation below 300 °C. The critical micelle concentration (CMC) values of the surfactants 2a and 2b were found to be 2.2 × 10−4 and 1.04 × 10−4 mol/L, and the corresponding surface tension (γCMC) values were 33.14 and 34.89 mN m−1, respectively. The surfactants exhibit excellent surface properties, which are comparable with conventional surfactants. The intrinsic viscosity of surfactant (2b) was studied at various temperatures and concentrations of multi‐component brine solution. The plot of natural logarithm of relative viscosity versus surfactant concentration obtained from Higiro et al. model best fit the surfactant behavior. Due to good salt resistance, excellent surface properties and thermal stability, the synthesized surfactant has potential to be used in various oil field applications such as enhanced oil recovery, fracturing, acid diversion, and well stimulation.Scopu
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