11 research outputs found

    Actinomyces viscosus Isolation from the Skin of a Cat

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    Actinomyces is an aerobic or microaerobic, Gram-positive, non-acid fast, filamentous, diphtheroidal rod or coccobacillus-shaped bacteria. Actinomycosisis is seen mostly as a dental disease of cattle, however it also occurs in other animal species such as dogs, cats, cows, goats and horses. This report describes a 1 year-old, female, mixed-breed, indoor cat which developed a purulent exudate around the interdigital area for 6 months. Despite various antibacterial treatments the skin lesions of the cat deteriorated. Anamnesis revealed that cat did not show any sign of pruritis however was eating a special diet for dermatologic disorders. The only sign on physical examination was a purulent exudate seen in the interdigital area. Hematological and biochemical profiles were within normal limits. Skin scrapes were negative for parasites and fungi. From the wound swab, Actinomyces viscosus was identified. According to the antibiotic susceptibility test, the isolate was susceptible to amoxicillin and amoxicillin/clavulanic acid. The cat received amoxicillin/clavulanic acid (8.75 mg/kg BID, IM) for a week. After the treatment, there was no discharge around the interdigital area. This case is of interest since Actinomyces viscosus has been rarely encountered in the skin of cats. Veterinarians should include A. viscosus in the differential diagnosis in case with dermal purulent discharge

    Dermatophytosis caused by a Chrysosporium species in two cats in Turkey: a case report

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    Dermatophytes are infectious agents and can cause the zoonotic disease dermatophytosis in animals and humans. Keratinophilic fungi and especially dermatophytes can be detected on the hair coat and skin of cats. The aim of this report is to present a rarely seen dermatophytic skin disease in cats. Two Persian cats, living in the same house, were found to be positive for Chyrososporium spp. using mycological culture. At that time the owner of the cats was undergoing chemotherapy for a mammary tumour. This treatment led to low immunity, intensive pruritus and also to scaling on the inside of her arms. Chrysosporium spp. were also detected in the cats' owner. Antifungal therapy was applied with fluconazole to both cats. Because of widespread lesions and alopecia, intravenous fluconazole was administered with a saline solution. The lesions improved inside a six week period after fluconazole therapy and no adverse effects were observed

    Dermatophytosis caused by a Chrysosporium species in two cats in Turkey: a case report

    No full text
    Dermatophytes are infectious agents and can cause the zoonotic disease dermatophytosis in animals and humans. Keratinophilic fungi and especially dermatophytes can be detected on the hair coat and skin of cats. The aim of this report is to present a rarely seen dermatophytic skin disease in cats. Two Persian cats, living in the same house, were found to be positive for Chyrososporium spp. using mycological culture. At that time the owner of the cats was undergoing chemotherapy for a mammary tumour. This treatment led to low immunity, intensive pruritus and also to scaling on the inside of her arms. Chrysosporium spp. were also detected in the cats' owner. Antifungal therapy was applied with fluconazole to both cats. Because of widespread lesions and alopecia, intravenous fluconazole was administered with a saline solution. The lesions improved inside a six week period after fluconazole therapy and no adverse effects were observed

    Expression levels of TRPC1 and TRPC6 ion channels are reciprocally altered in aging rat aorta: implications for age-related vasospastic disorders

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    We previously showed that the expression of transient receptor potential canonical (TRPC)6 ion channel elevated when TRPC1 was knocked down in A7r5 cultured vascular smooth muscle cells. Therefore, the purpose of this study was to explore whether TRPC6 is also upregulated in aging rat aorta comparable to that of TRPC1 in longitudinal in vivo aging model. We further investigated a possible causal relationship between altered phenylephrine-induced contractions and the expression levels of TRPC6, a purported essential component of alpha-adrenergic receptor signaling in aging aorta. Immunoblot analysis showed that TRPC1 protein levels significantly decreased whereas TRPC6 increased drastically in aorta from 16- to 20-month-old rats compared to that from 2 to 4 months. Immunohistochemical data demonstrated spatial changes in TRPC6 expression within the smooth muscle layers along with increased detection in the adventitia of the aged rat aorta. The phenylephrine-induced contractions were potentiated in aging aorta. In conclusion, based on this aging model, TRPC6 overexpression could be related with TRPC1 downregulation and might be responsible for the increased adrenoceptor sensitivity which contributes to the development of age-related vasospastic disorders
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