4,608 research outputs found
Wildlife disease elimination and 1 density dependence
Disease control by managers is a crucial response to emerging wildlife epidemics, yet the means of control may be limited by the method of disease transmission. In particular, it is widely held that population reduction, while effective for controlling diseases that are subject to density-dependent transmission, is ineffective for controlling diseases that are subject to frequency-dependent transmission. We investigate control for horizontally transmitted diseases with frequency-dependent transmission where the control is via nonselective (for infected animals) culling or harvesting and the population can compensate through density-dependent recruitment or survival. Using a mathematical model, we show that culling or harvesting can eradicate the disease, even when transmission dynamics are frequency-dependent. E 24 radication can be achieved under frequency-dependent transmission when density-dependent population regulation induces compensatory growth of new, healthy individuals, which has the net effect of reducing disease prevalence by dilution. We also show that if harvest is used simultaneously with vaccination and there is high enough transmission coefficient, application of both controls may be less efficient than when vaccination alone is used. We illustrate the effects of these control approaches on disease prevalence using assumed parameters for chronic wasting disease in deer where the disease is transmitted directly among deer and through the environment
How linear features alter predator movement and the functional\ud response
In areas of oil and gas exploration, seismic lines have been reported to alter the movement patterns of wolves (Canis lupus). We developed a mechanistic first passage time model, based on an anisotropic elliptic partial differential equation, and used this to explore how wolf movement responses to seismic lines influence the encounter rate of the wolves with their prey. The model was parametrized using 5 min GPS location data. These data showed that wolves travelled faster on seismic lines and had a higher probability of staying on a seismic line once they were on it. We simulated wolf movement on a range of seismic line densities and drew implications for the rate of predator–prey interactions as described by the functional response. The functional response exhibited a more than linear increase with respect to prey density (type III) as well as interactions with seismic line density. Encounter rates were significantly higher in landscapes with high seismic line density and were most pronounced at low prey densities. This suggests that prey at low population densities are at higher risk in environments with a high seismic line density unless they learn to avoid them
An inquiry-based learning approach to teaching information retrieval
The study of information retrieval (IR) has increased in interest and importance with the explosive growth of online information in recent years. Learning about IR within formal courses of study enables users of search engines to use
them more knowledgeably and effectively, while providing the starting point for the explorations of new researchers into novel search technologies. Although IR can be taught in a traditional manner of formal classroom instruction with students being led through the details of the subject and expected to reproduce this in assessment, the nature of IR as a topic makes it an ideal subject for inquiry-based learning approaches to teaching. In an inquiry-based learning approach students are introduced to the principles of a subject and then encouraged to develop their understanding by solving structured or open problems. Working through solutions in subsequent class discussions enables students to appreciate the availability of alternative solutions as proposed by their classmates. Following this approach students not only learn the details of IR techniques, but significantly, naturally learn to apply them in solution of problems. In doing this they not only gain an appreciation of alternative solutions to a problem, but also how to assess their relative strengths and weaknesses. Developing confidence and skills in problem solving enables student assessment to be structured around solution of problems. Thus students can be assessed on the basis of their understanding and ability to apply techniques, rather simply their skill at reciting facts. This has the additional benefit of encouraging general problem solving skills which can be of benefit in other subjects. This approach to teaching IR was successfully implemented in an undergraduate module where students were
assessed in a written examination exploring their knowledge and understanding of the principles of IR and their ability to apply them to solving problems, and a written assignment based on developing an individual research proposal
Field study of voluntary health organizations in Thailand, Taiwan, the Philippines, Indonesia, and Korea
Willow on yellowstone's northern range: Evidence for a trophic cascade?
Reintroduction of wolves (Canis lupus) to Yellowstone National Park in 1995-1996 has been argued to promote a trophic cascade by altering elk (Cervus elaphus) density, habitat-selection patterns, and behavior that, in turn, could lead to changes within the plant communities used by elk. We sampled two species of willow (Salix boothii and S. geyeriana) on the northern winter range to determine whether (1) there was quantitative evidence of increased willow growth following wolf reintroduction, (2) browsing by elk affected willow growth, and (3) any increase in growth observed was greater than that expected by climatic and hydrological factors alone, thereby indicating a trophic cascade caused by wolves. Using stem sectioning techniques to quantify historical growth patterns we found an approximately twofold increase in stem growth-ring area following wolf reintroduction for both species of willow. This increase could not be explained by climate and hydrological factors alone; the presence of wolves on the landscape was a significant predictor of stem growth above and beyond these abiotic factors. Growth-ring area was positively correlated with the previous year's ring area and negatively correlated with the percentage of twigs browsed from the stem during the winter preceding growth, indicating that elk browse impeded stem growth. Our results are consistent with the hypothesis of a behaviorally mediated trophic cascade on Yellowstone's northern winter range following wolf reintroduction. We suggest that the community-altering effects of wolf restoration are an endorsement of ecological-process management in Yellowstone National Park
On the Asymmetries of Extended X-ray Emission from Planetary Nebulae
Chandra X-ray Observatory (CXO) images have revealed that the X-ray emitting
regions of the molecule-rich young planetary nebulae (PNs) BD+30 3639 (BD+30)
and NGC 7027 are much more asymmetric than their optical nebulosities. To
evaluate the potential origins of these X-ray asymmetries, we analyze X-ray
images of BD+30, NGC 7027, and another planetary nebula resolved by CXO, NGC
6543, within specific energy bands. Image resolution has been optimized by
sub-pixel repositioning of individual X-ray events. The resulting
subarcsecond-resolution images reveal that the soft (E < 0.7 keV) X-ray
emission from BD+30 is more uniform than the harder emission, which is largely
confined to the eastern rim of the optical nebula. In contrast, soft X-rays
from NGC 7027 are highly localized and this PN is more axially symmetric in
harder emission. The broad-band X-ray morphologies of BD+30 and NGC 7027 are
highly anticorrelated with their distributions of visual extinction, as
determined from high-resolution, space- and ground-based optical and infrared
imaging. Hence, it is likely that the observed X-ray asymmetries of these
nebulae are due in large part to the effects of nonuniform intranebular
extinction. However, the energy-dependent X-ray structures in both nebulae and
in NGC 6543 -- which is by far the least dusty and molecule-rich of the three
PNs, and displays very uniform intranebular extinction -- suggests that other
mechanisms, such as the action of collimated outflows and heat conduction, are
also important in determining the detailed X-ray morphologies of young
planetary nebulae.Comment: 33 pages, 12 figures; to appear in the Astrophysical Journa
Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins.
Sphingolipids have important roles in membrane and lipoprotein structure and in cell regulation as second messengers for growth factors, differentiation factors, cytokines, and a growing list of agonists. Bioactive sphingolipids are formed both by the turnover of complex sphingolipids and as intermediates of sphingolipid biosynthesis. Usually, the amounts are highly regulated; however, by inhibiting ceramide synthase, fumonisins block the biosynthesis of complex sphingolipids and cause sphinganine (and sometimes sphingosine) to accumulate. Where the mechanism has been studied most thoroughly, the accumulation of sphingoid bases is a primary cause of the toxicity of fumonisin B (FB). Nonetheless, the full effects of fumonisins probably involve many biochemical events. The elevations in sphingoid bases also affect the amounts of other lipids, including the 1-phosphates and N-acetyl derivatives of sphinganine. Furthermore, the aminopentol backbone of FB1 (AP1) is both an inhibitor and a substrate for ceramide synthase, and the resultant N-palmitoyl-AP1 (PAP1) is an even more potent inhibitor of ceramide synthase (presumably as a product analog). PAP1 is 10 times more toxic than FB1 or AP1 for HT-29 cells in culture, and hence may play a role in the toxicity of nixtamalized fumonisins. All these processes--the effects of fumonisins on sphingolipid metabolism, the pathways altered by perturbation of sphingolipid metabolism, and the complex cellular behaviors regulated by sphingolipids--must be borne in mind when evaluating the pathologic effects of fumonisins
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