1,493 research outputs found

    Leggett mode in a strong-coupling model of iron arsenide superconductors

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    Using a two-orbital model of the superconducting phase of the pnictides, we compute the spectrum of the Leggett mode -- a collective excitation of the phase of the superconducting gap known to exist in multi-gap superconductors -- for different possible symmetries of the superconducting order parameter. Specifically, we identify the small regions of parameter space where the Leggett mode lies below the two-particle continuum, and hence should be visible as a sharp resonance peak. We discuss the possible utility of the Leggett mode in distinguishing different momentum dependencies of the superconducting gap. We argue that the observation of a sharp Leggett mode would be consistent with the presence of strong electron-electron correlations in iron-based superconductors. We also emphasize the importance of the orbital character of the Leggett mode, which can result in an experimental observation of the mode in channels other than A1gA_{1g}

    On the Nature of the Response of the General Purpose Heat Source to the Impact of Large Solid Rocket Motor Casing Fragments

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    After the Challenger (STS-51L)accident new tests were performed to assess the response of the GPHS module to large fragment impacts. The subject of this paper is the analytical process used to perform macro calibrations of the analytical methods and their application to predict the GPHS modules' response to serially increasing levels of test environment complexity. Sensitivity studies were performed to generate a fueled-clad-distortion-response statistical database for use in a Monte Carlo based fuel release analysis. The analyses showed that the iridium fueled clads in the GPHS-RTG have high resistance to distortion induced by the impact of large, high velocity (>200 m/s), SRM casing fragments. It was concluded that the impact of large SRM fragments will cause little clad disruption at early Mission Elapsed Time (MET), and that the effects of these impacts will be less severe than had initially been believe. There are three copies in the file

    Data-intensive research in physics: challenges and perspectives

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    Raman Research Institute (RRI) in recent years has been engaged in data-intensive research. The paper aims to understand the challenges faced by graduate students and their perspectives in data-intensive research at RRI regarding datatypes; collection methods; storage and access; data processing; legal and ethical issues. Questionnaire survey method and information extraction from ETD repository of RRI were used for data collection. Graduate students have expressed their desire for a better technical infrastructure, and need for training courses on different aspects of data related research and acquisition of data processing software. Observations in this study indicate that researchers are not well informed about some of the social issues associated with data and research such as legal aspects, ethical issues, plagiarism, data citation attributions, etc,. The study recommends steps to empower research students to handle the challenges in data-intensive research

    Immune thrombocytopenic purpura in a 5-month-old female with rotavirus infection

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    No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65028/1/22368_ftp.pd

    Mechanical characterization of lime-cement mortars: E-modulus and fracture energy

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    In masonry constructions, the choice of mortar composition is usually guided by requirements of the final application, which could range from new constructions to conservation projects. Often, lime and cement are combined together, to overcome their individual shortcomings and consequently serve as a suitable binder in masonry mortars. Depending on their proportion in the mixture, it may be possible to obtain a desired range of characteristics in different mechanical properties like strength and stiffness. However, existing studies exploring this subject are scarce. Therefore, this work aims at adopting a systematic approach to studying the effect of different lime-cement ratios on the mechanical properties of masonry mortars, specifically targeting a discussion on E-modulus and fracture energy. Three distinct mixes with quantities of lime varying from 25% to 67% (by volume) have been studied. The benefits and trade-offs associated with substitution of different quantities of cement with lime in mortars, have been explored with regard to resistance to crack propagation.EuLA - European Lime Association. FCT PhD grant for the 1st author. European Lime Association for funding this project. Funding provided by the Portuguese Foundation for Science and Technology (FCT) to the Research Project PTDC/ECM-EST/1056/2014 (POCI-01-0145-FEDER-016841), as well to the Research Unit ISISE (POCI-01-0145-FEDER-007633

    Mechanical properties of lime–cement masonry mortars in their early ages

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    Lime–cement mortars are often used in restoration of existing buildings (especially twentieth century onward) as well as new constructions, in order to combine the individual strengths of either type of binder. Despite the knowledge that mortars have a significant impact on the non-linear mechanical behaviour of masonry from the earliest moments of construction, literature that systematically quantifies the impact of adding lime to cement mortars, or vice versa is scarce and scattered. This work is therefore focussed on bridging the research gap that exists in lime–cement masonry mortars with regard to their mechanical properties in the early ages (up to 7 days of curing). Five different mix compositions have been studied with 1:3 binder-aggregate ratio and 10% to 75% lime content in the binder, both by volume. Changes in properties like mechanical strength and stiffness along with ultrasound pulse velocity have been quantified, correlated and associated with change in quantity of lime in the binder (by volume) of the mortar. It was found that every 10% increase in the quantity of lime in the binder led to a 14% decrease in mechanical strength and a corresponding 12% decrease in stiffness, at 7 days of curing age. E-modulus was found to evolve faster than flexural strength, which in turn was found to evolve faster than compressive strength. Impact of curing temperature and the concept of activation energy has been addressed for the mix 1:1:6 (Cement:Lime:Sand).EuLA - European Lime Association; FCT Phd Scholarship of 1st author. Portuguese Foundation for Science and Technology (FCT) to the Research Project PTDC/ECM-EST/1056/2014 (POCI-01-0145-FEDER-016841), as well to the Research Unit ISISE (POCI-01-0145-FEDER-007633

    Aberrant SGK1 Transcription in LNCaP: A Novel Feed-back Mechanism of TGF-beta1 Regulation in Prostate Carcinogenesis

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    SGK1, a serum- and glucocorticoid-inducible kinase implicated in cancer, is regulated by TGF-beta1 and PI3-kinase. In a comparative study of different benign and cancerous breast and prostate cells, we demonstrate in this study that exon 11 deletion in SGK1 occurs only in LNCaP prostate cancer cells in association with the deficient TGF-beta1 mRNA message and FOXO3A-driven promoter activity. Using protein modeling approaches, we discovered that exon11 deletion in SGK1 could redistribute electrostatic surface potential around the major kinase domain and affect phosphorylation of SGK1 target proteins including FOXO3A. Concordantly, we found that LNCaP cells displayed FOXO3A hyperphosphorylation at the Ser218/321 (a site next to Ser315 with the marked SGK1 preference) along with changes in gene expression profile of TGF-beta relevant regulators (such as SMAD2/4, MAD4 and SKIP). Oncomine-interactome analysis further validated a possibility of reciprocal TGF-beta1 regulation by its transcriptional target SGK1 through alterations in FOXO/SMAD and steroid hormone nuclear receptor interactions

    Impact of moisture curing conditions on mechanical properties of lime-cement mortars in early ages

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    Blended lime-cement mortars, which are frequently used in masonry construction, mature as a result of two different phenomena, namely lime carbonation and cement hydration. At any given temperature, these two processes require different moisture conditions for optimal contribution to the mechanical performance of mortar. Since mortars have an impact on the non-linear behavior of masonry from the time of application, it is necessary to optimize their performance with regard to composition and curing conditions. It is expected that a suitable choice of mortar in conjunction with the unit will provide better performance of masonry by reducing risk of cracking and facilitating durability of masonry. This work aims at studying the impact of environmental relative humidity (RH) in the curing process of lime-cement mortars, focusing on their early age behavior. Two mixes with 25% and 67% lime in the binder (by volume), binder-aggregate ratio of 1:3 and target workability of 175±10 mm were chosen for the study. Mechanical properties like compressive strength, flexural strength, open porosity and density have been studied at 2, 4 and 7 days of curing age. Temperature was kept constant at 20°C while three distinct environmental humidity conditions were tested: sealed environment, 90% RH, and 60% RH. Results have been explored to understand how the evolution of basic mechanical properties changed as a function of curing RH. Curing in sealed conditions and 90% RH did not result in similar values of strength, in either of the two blended mixes. For the mix with 25% lime - 3C1L12S (25%), hardening appeared to be guided by cement hydration. For the mix with 67% lime - 1C2L9S (67%), curing in RH of 60% and 90% resulted in almost the same strength at day 7, demonstrating that lime carbonation may be important earlier than 7 daysEuLA - European Lime Association, FCT PhD Grant of 1st Author. European Lime Association for funding this project. Funding provided by the Portuguese Foundation for Science and Technology (FCT) to the Research Project PTDC/ECMEST/1056/2014 (POCI-01-0145-FEDER-016841), Research Unit ISISE (POCI-01-0145-FEDER-007633), and scholarship SFRH/BD/137358/201
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