929 research outputs found
The Association between Food Insecurity, Glycemic Control, Self-Care, and Quality of Life in Adults with Type 2 Diabetes
Food insecurity is the inability to obtain adequate nutritious food. Therefore, the study assessed the relationship between food insecurity, glycemic control, self-care behaviors, and quality of life in adults with type 2 diabetes (T2DM).
Cross sectional study of 356 adults with T2DM recruited from an academic medical center and a veterans affairs medical center. The independent predictor was food insecurity, and the outcomes were glycosylated hemoglobin A1c, self-care behaviors, and quality of life (QOL). Logistic regression was used to assess the independent factors associated with food insecurity. Multiple linear regression was used to assess the association between food insecurity and outcomes. Stata was used for the analyses.
The majority (88%) was ≥50 years old, male (70%), and non-Hispanic black (55%). Thirty-five percent were food insecure. Compared to those who had 16 years of education were less likely to be food insecure (Odds ratio (OR) 0.25; 95% Confidence Interval (CI) 0.07, 0.92). Compared to those making \u3c20,000-35,000 (OR 0.15, 95% 0.06, 0.38) were less likely to be food insecure. In adjusted modeling, food insecurity was marginally associated with glycemic control (βeta coefficient =-0.41; 95% CI -0.85, 0.02), and not significantly associated with self-care behaviors or QOL.
In this sample of adults with T2DM, food insecurity was significantly associated with education and income and marginally associated with glycemic control. Further research is needed to assess the relationship between these factors
Nonconventional Large Deviations Theorems
We obtain large deviations theorems for nonconventional sums with underlying
process being a Markov process satisfying the Doeblin condition or a dynamical
system such as subshift of finite type or hyperbolic or expanding
transformation
Reflecting on Malaysian teacher trainees’ journals
Purpose – In this study, 37 English Language Teaching (ELT) teacher trainees from a Malaysian university conducted an action-research project to determine whether journals kept during their fieldwork in primary schools located in an area close to the university allowed them to reflect on their beliefs and behaviors in the classroom. Methodology – Themes were revealed using emergent coding in their journals. Van Manen’s (1977) three-stage model (practical, technical and critical) was used to determine the issues raised and the level of critical reflection reached in the journal entries Findings – The findings indicated that the teacher trainees demonstrated practical and technical level thinking, but rarely rose to the critical level of reflection. Nonetheless, they also demonstrated changes in their beliefs and behaviours, essential for professional development.Significance – Reflective thinking is critical to teaching and is important in the United States and in countries striving to replicate its pedagogical tools and techniques. However, many Western practices associated with the nurturing of critical thinking are not familiar to Malaysian teacher trainees.We conclude that prospective teachers here do use their journals to reflect on their educational practice, but not at the deepest levels of insight. Critical thinking must be taught to Malaysian teacher trainees and filtered through the local culture if it is to improve teaching and learning in the nation’s classrooms
The relationship between the BRAF p.V600E mutation and a family history of CRC in the early-onset CRC cases from the Australasian Colon Cancer Family Study
Transcription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection.
A majority of individuals infected with human immunodeficiency virus (HIV) have inadequate access to antiretroviral therapy and ultimately develop debilitating oral infections that often correlate with disease progression. Due to the impracticalities of conducting host-microbe systems-based studies in HIV infected patients, we have evaluated the potential of simian immunodeficiency virus (SIV) infected rhesus macaques to serve as a non-human primate model for oral manifestations of HIV disease. We present the first description of the rhesus macaque oral microbiota and show that a mixture of human commensal bacteria and "macaque versions" of human commensals colonize the tongue dorsum and dental plaque. Our findings indicate that SIV infection results in chronic activation of antiviral and inflammatory responses in the tongue mucosa that may collectively lead to repression of epithelial development and impact the microbiome. In addition, we show that dysbiosis of the lingual microbiome in SIV infection is characterized by outgrowth of Gemella morbillorum that may result from impaired macrophage function. Finally, we provide evidence that the increased capacity of opportunistic pathogens (e.g. E. coli) to colonize the microbiome is associated with reduced production of antimicrobial peptides
Rapidly Decaying Supernova 2010X: A Candidate ".Ia" Explosion
We present the discovery, photometric and spectroscopic follow-up
observations of SN 2010X (PTF 10bhp). This supernova decays exponentially with
tau_d=5 days, and rivals the current recordholder in speed, SN 2002bj. SN 2010X
peaks at M_r=-17mag and has mean velocities of 10,000 km/s. Our light curve
modeling suggests a radioactivity powered event and an ejecta mass of 0.16
Msun. If powered by Nickel, we show that the Nickel mass must be very small
(0.02 Msun) and that the supernova quickly becomes optically thin to
gamma-rays. Our spectral modeling suggests that SN 2010X and SN 2002bj have
similar chemical compositions and that one of Aluminum or Helium is present. If
Aluminum is present, we speculate that this may be an accretion induced
collapse of an O-Ne-Mg white dwarf. If Helium is present, all observables of SN
2010X are consistent with being a thermonuclear Helium shell detonation on a
white dwarf, a ".Ia" explosion. With the 1-day dynamic-cadence experiment on
the Palomar Transient Factory, we expect to annually discover a few such
events.Comment: 6 pages, 5 figures; Minor Changes; Note correction in Fig 4 caption;
published by ApJ
Connectivity of Soft Random Geometric Graphs Over Annuli
Nodes are randomly distributed within an annulus (and then a shell) to form a
point pattern of communication terminals which are linked stochastically
according to the Rayleigh fading of radio-frequency data signals. We then
present analytic formulas for the connection probability of these spatially
embedded graphs, describing the connectivity behaviour as a dense-network limit
is approached. This extends recent work modelling ad hoc networks in non-convex
domains.Comment: 12 pages, 6 figure
The Relationship between Asthma and Depression in Primary Care Patients: A Historical Cohort and Nested Case Control Study
Asthma and depression are common health problems in primary care. Evidence of a relationship between asthma and depression is conflicting. Objectives: to determine 1. The incidence rate and incidence rate ratio of depression in primary care patients with asthma compared to those without asthma, and 2. The standardized mortality ratio of depressed compared to non-depressed patients with asthma.A historical cohort and nested case control study using data derived from the United Kingdom General Practice Research Database. Participants: 11,275 incident cases of asthma recorded between 1/1/95 and 31/12/96 age, sex and practice matched with non-cases from the database (ratio 1∶1) and followed up through the database for 10 years. 1,660 cases were matched by date of asthma diagnosis with 1,660 controls. Main outcome measures: number of cases diagnosed with depression, the number of deaths over the study period.The rate of depression in patients with asthma was 22.4/1,000 person years and without asthma 13.8 /1,000 person years. The incident rate ratio (adjusted for age, sex, practice, diabetes, cardiovascular disease, cerebrovascular disease, smoking) was 1.59 (95% CI 1.48–1.71). The increased rate of depression was not associated with asthma severity or oral corticosteroid use. It was associated with the number of consultations (odds ratio per visit 1.09; 95% CI 1.07–1.11). The age and sex adjusted standardized mortality ratio for depressed patients with asthma was 1.87 (95% CI: 1.54–2.27).Asthma is associated with depression. This was not related to asthma severity or oral corticosteroid use but was related to service use. This suggests that a diagnosis of depression is related to health seeking behavior in patients with asthma. There is an increased mortality rate in depressed patients with asthma. The cause of this needs further exploration. Consideration should be given to case-finding for depression in this population
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