915 research outputs found

    Concealment Conserving the Data Mining of Groups & Individual

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    We present an overview of privacy preserving data mining, one of the most popular directions in the data mining research community. In the first part of the chapter, we presented approaches that have been proposed for the protection of either the sensitive data itself in the course of data mining or the sensitive data mining results, in the context of traditional (relational) datasets. Following that, in the second part of the chapter, we focused our attention on one of the most recent as well as prominent directions in privacy preserving data mining: the mining of user mobility data. Although still in its infancy, privacy preserving data mining of mobility data has attracted a lot of research attention and already counts a number of methodologies both with respect to sensitive data protection and to sensitive knowledge hiding. Finally, in the end of the chapter, we provided some roadmap along the field of privacy preserving mobility data mining as well as the area of privacy preserving data mining at large

    Comparative study of dexmedetomidine and tramadol for control of post-spinal anesthesia shivering

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    Background and Aim: Dexmedetomidine, a congener of clonidine is an α2 adrenoceptor agonist, commonly used for sedation, alsoknown to have antishivering potential. Its use as an agent to treat and control post-spinal anesthesia shivering has been inadequatelystudied. This study is thus aimed to evaluate the efficacy, hemodynamic changes and side effects of dexmedetomidine in comparisonto tramadol when used to control post-spinal anesthesia shivering. Materials and Methods: A prospective randomized, and doubleblindstudy was conducted in 60 ASA Grade I and II patients of either gender, aged between 18 and 60 years, undergoing varioussurgical procedure under spinal-anesthesia and developing shivering. The patients were randomized into two groups of n = 30each to receive either dexmedetomidine - 0.5 μg/kg (Group D) or tramadol - 0.5 mg/kg (Group T) as an intravenous infusion onappearance of shivering. The time of onset, grade of shivering, time taken for cessation of shivering, response rate, and adverseeffect were observed at scheduled intervals. SPSS-20 was used for statistical analysis, unpaired t-test for numerical data andchi-square test for categorical data. Results: Both the drugs effectively controlled shivering, taking almost the same time for itscessation. It was observed that patients in Group D were found to have a greater sedation score, whereas the side effects such asnausea and vomiting requiring treatment was more in Group T. The incidence of recurrence of shivering was higher in Group T.Conclusions: Dexmedetomidine effectively controls shivering taking almost the same time for cessation as that of tramadol. Itprovides an additional benefit of intraoperative sedation

    Differentiation of Malaysian farmed and commercialised edible bird's nests through nutritional composition analysis

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    The growing demand of edible bird’s nest (EBN) worldwide as well as competition from neighbouring countries has made the EBN industry one of the rising industries in Malaysia with stringent exportation requirement by China. However, as majority of the EBN products in the market is in commercialised form, studies on the nutritional composition of these commercialised EBN in comparison with farmed, raw EBN are limited. The farmed EBN samples were taken from 4 different regions of Malaysia: Perak (central), Kelantan (eastern), Johor (southern) and Sarawak (west Borneo) while the commercialised sample was obtained from a local drug store. Proximate, amino acid and elemental composition were performed on these EBNs. Farmed EBNs mainly comprised protein followed by carbohydrate while the commercialised EBN had similar protein and carbohydrate composition. The total collection of essential amino acid in commercialised EBN was higher (237.9 mg/g protein) compared to the farmed EBN which was between 156.81 − 236.6 mg amino acid/g protein. Among the essential amino acids, valine was found to be highest in both commercialised and farmed EBN. The differences between the nutritional compositions of EBNs could be due to the process of commercialisation of the EBN as well as seasonal, breeding sites and diet of the swiftlets. Farmed EBN therefore can be considered to be more nutritional due to higher protein levels

    Analysis of goal scoring period in major European football league winners 2019/2020

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    One of the most watched football tournaments in the world is the European football league (e.g., La Liga, Bundesliga, Serie A, etc.). Football matches are divided into two halves. At the end of the game, the number of goals scored can be used to determine the winner. Therefore, the objective of this study was to analyze and compare the goals scored between the first half and second half period among the winners of each top European League 2019/2020 competition. The Mann-Whitney U test was used to evaluate a total of 406 goals from 175 games from the official website and YouTube highlights. Only Liverpool, England's Premier League, showed more goals in the first half, whereas the majority of the winners—Real Madrid, Spain's La Liga, Juventus, Italy's Serie A TIM, Bayern Munich, Germany's Bundesliga, and Paris Saint-German, France's Ligue 1 Uber Eats—scored more goals in the second half. The results indicated that there were significant differences in goals scored between the first and second half periods in La Liga and Serie A TIM, p < .05. In conclusion, Real Madrid and Juventus fully utilized the disadvantages of their opponents to score a goal to win a match and competition. As the time moves towards the end of the matches, the player’s fitness components, mental aspect, and team tactical become the crucial factors of team differentiation. This study recommends comparing goal scoring across several continents in the future

    Mollusk Shell Waste as Composite Photocatalyst for Methylene Blue Removal

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    Mollusk shell is abundant in particular areas and frequently deposited in landfills, contributing to environmental pollution. However, mollusk shell waste has been proven as an absorbent that has a high possibility of acting as a photocatalyst when integrated with metal support in composite form due to the synergistic effect. Therefore, in this study, mussel and cockle shells as agricultural wastes were selected to be innovated as support for photocatalysts. The solid-state dispersion (SSD) method was used to prepare a composite photocatalyst where mussel and cockle were integrated with titanium dioxide (TiO2) nanoparticles at a ratio of 9:1. In total, 100% of mussel and cockle were used as control samples. The prepared composite photocatalyst was evaluated with methylene blue (MB) removal in the suspension system. The result reveals that mussel/TiO2 and cockle/TiO2 composite photocatalyst show 25.92 and 24.08% for MB removal within 2 hours. It is due to the prepared composite photocatalyst particle sizes, where mussel/TiO2 and cockle/TiO2 were 259 and 268 nm, respectively. It is interesting to note that the prepared composite photocatalyst particle size should be in nanosize, where it can enhance the photocatalytic performance. Overall, agricultural waste should be utilized to ensure a clean environment for future generations

    The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design.

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    During recent decades, Bangladesh has experienced a rapid epidemiological transition from communicable to non-communicable diseases. Coronary heart disease (CHD), with myocardial infarction (MI) as its main manifestation, is a major cause of death in the country. However, there is limited reliable evidence about its determinants in this population. The Bangladesh Risk of Acute Vascular Events (BRAVE) study is an epidemiological bioresource established to examine environmental, genetic, lifestyle and biochemical determinants of CHD among the Bangladeshi population. By early 2015, the ongoing BRAVE study had recruited over 5000 confirmed first-ever MI cases, and over 5000 controls "frequency-matched" by age and sex. For each participant, information has been recorded on demographic factors, lifestyle, socioeconomic, clinical, and anthropometric characteristics. A 12-lead electrocardiogram has been recorded. Biological samples have been collected and stored, including extracted DNA, plasma, serum and whole blood. Additionally, for the 3000 cases and 3000 controls initially recruited, genotyping has been done using the CardioMetabochip+ and the Exome+ arrays. The mean age (standard deviation) of MI cases is 53 (10) years, with 88 % of cases being male and 46 % aged 50 years or younger. The median interval between reported onset of symptoms and hospital admission is 5 h. Initial analyses indicate that Bangladeshis are genetically distinct from major non-South Asian ethnicities, as well as distinct from other South Asian ethnicities. The BRAVE study is well-placed to serve as a powerful resource to investigate current and future hypotheses relating to environmental, biochemical and genetic causes of CHD in an important but under-studied South Asian population.The Gates Cambridge Trust has supported Dr Chowdhury. Epidemiological fieldwork in BRAVE has been supported by grants to investigators at the Cardiovascular Epidemiology Unit, University of Cambridge. The Cardiovascular Epidemiology Unit is underpinned by programme grants from the British Heart Foundation (RG/13/13/30194), the UK Medical Research Council (MR/L003120/1), and the UK National Institute of Health Research Cambridge Biomedical Research Centre. BRAVE has received support for genetic assays from the European Research Council (ERC-2010-AdG-20100317), European Commission Framework 7 (Grant Agreement number: 279233), and the Cambridge British Heart Foundation Centre for Excellence in Cardiovascular Science; We would like to acknowledge the contributions of the following individuals: Cardiology Research Group in Bangladesh Mohammad Afzalur Rahman, Mohammad Abdul Kader Akanda, M Atahar Ali, Mir Jamal Uddin, SM Siddiqur Rahman, Amal Kumar Choudhury, Md. Mamunur Rashid, Nazir Ahmed Chowdhury, Mohammad Abdullahel Baqui, Kajal Kumar Karmoker, Mohammad Golam Azam; Setting up/implementation of fieldwork in Bangladesh Abbas Bhuiya, Susmita Chowdhury, Kamrun Nahar, Neelima Das, Proshon Roy, Sumona Ferdous, Taposh Kumar Biswas, Abu Sadat Mohammad Sayed Sharif, Ranjit Shingha, Rose Jinnath Tomas, Babulal Parshei, Mabubur Rahman, Mohammad Emon Hossain, Akhirunnesa Mily, AK Mottashir Ahmed, Sati Chowdhury, Sushila Roy, Dipak Kanti Chowdhury, Swapan Kumar Roy; Epidemiological/statistical support in Cambridge Stephen Kaptoge, Simon Thompson, Angela Wood, Narinder Bansal, Anna Ramond, Clare Oliver-Williams, Marinka Steur, Linda O’Keeffe, Eleni Sofianopoulou, Setor Kunutsor, Donal Gorman, Oscar H Franco, Malcolm Legget, Pinal Patel, Marc Suhrcke, Sylvaine Bruggraber, Jonathan Powell; Data management Matthew Walker, Steve Ellis, Shawkat Jahangir, Habibur Rahman, Rifat Hasan Shammi, Shafqat Ullah, Mohammad Abdul Matin and Administration Beth Collins, Hannah Lombardi, Binder Kaur, Rachel Henry, Marilena Papanikolaou, Robert Smith, Abdul Wazed, Robert Williams, Julie Jenkins, Keith Hoddy.This is the final published version of the article. It was originally published in the European Journal of Epidemiology (Chowdhury R, et al., European Journal of Epidemiology, 2015, doi:10.1007/s10654-015-0037-2). The final version is available at http://dx.doi.org/10.1007/s10654-015-0037-

    Implementing a guideline for the treatment of type 2 diabetics: results of a Cluster- Randomized Controlled Trial (C-RCT)

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    <p>Abstract</p> <p>Background</p> <p>In Italy many diabetics still lack adequate care in general practice. We assessed the effectiveness of different strategies for the implementation of an evidence-based guideline for the management of non-complicated type 2 diabetes among General Practitioners (GPs) of Lazio region.</p> <p>Methods</p> <p>Three-arm cluster-randomised controlled trial with GPs as units of randomisation (clusters). 252 GPs were randomised either to an active strategy (training module with administration of the guideline), or to a passive dissemination (administration of the guideline only), or to usual care (control). Data on prescriptions of tests and drugs were collected by existing information systems, whereas patients' data came from GPs' databases. Process outcomes were measured at the cluster level one year after the intervention. Primary outcomes concerned the measurement of glycosilated haemoglobin and the commissioning of micro- and macrovascular complications assessment tests. In order to assess the physicians' drug prescribing behaviour secondary outcomes were also calculated.</p> <p>Results</p> <p>GPs identified 6395 uncomplicated type 2 patients with a high prevalence of cardiovascular risk factors. Data on GPs baseline performance show low proportions of glycosilated haemoglobin assessments. Results of the C-RCT analysis indicate that the active implementation strategy was ineffective relating to all primary outcomes (respectively, OR 1.06 [95% IC: 0.76–1.46]; OR 1.07 [95% IC: 0.80–1.43]; OR 1.4 [95% IC:0.91–2.16]. Similarly, passive dissemination of the guideline showed no effect.</p> <p>Conclusion</p> <p>In our region compliance of GPs with guidelines was not enhanced by a structured learning programme. Implementation through organizational measures appears to be essential to induce behavioural changes.</p> <p>Trial registration</p> <p>ISRCTN80116232</p

    Is population screening for abdominal aortic aneurysm cost-effective?

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    <p>Abstract</p> <p>Background</p> <p>Ruptured abdominal aortic aneurysm (AAA) is responsible for 1–2% of all male deaths over the age of 65 years. Early detection of AAA and elective surgery can reduce the mortality risk associated with AAA. However, many patients will not be diagnosed with AAA and have therefore an increased death risk due to the untreated AAA. It has been suggested that population screening for AAA in elderly males is effective and cost-effective. The purpose of this study was to perform a systematic review of published cost-effectiveness analyses of screening elderly men for AAA.</p> <p>Methods</p> <p>We performed a systematic search for economic evaluations in NHSEED, EconLit, Medline, Cochrane, Embase, Cinahl and two Scandinavian HTA data bases (DACEHTA and SBU). All identified studies were read in full and each study was systematically assessed according to international guidelines for critical assessment of economic evaluations in health care.</p> <p>Results</p> <p>The search identified 16 cost-effectiveness studies. Most studies considered only short term cost consequences. The studies seemed to employ a number of "optimistic" assumptions in favour of AAA screening, and included only few sensitivity analyses that assessed less optimistic assumptions.</p> <p>Conclusion</p> <p>Further analyses of cost-effectiveness of AAA screening are recommended.</p
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