3,978 research outputs found

    A digital system for accurate time sector division of a spin stabilized vehicle

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    Digital system for accurate time sector division of spin stabilized vehicle as used on Pioneer space probe

    Cosmic ray tables - Asymptotic directions, variational coefficients and cut-off rigidities IQSY instruction manual no. 10

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    Cosmic ray deflections in geomagnetic field, variational coefficients, and diurnal intensity variations - table

    The abnormal electrical and optical properties in Na and Ni codoped BiFeO3 nanoparticles

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    The effect of Fit-checking material and various subsequent cleaning methods on the wettability of the dentin surface: an in vitro study

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    Background: GC Fit-checker is a modified polyvinyl siloxane impression material exclusively used to check the internal fit and improve the marginal fit of indirect restorations. An unpolymerized organic film is known to be leftover on the bonding surfaces after the silicone disclosing procedure. Residual silicone film being hydrophobic may alter the wettability of the cement to the tooth/metal surface, thus having a detrimental effect on the bond strength and retention of the restoration.   Aim: This study aimed to evaluate the wetting of luting liquid (GIC) to tooth dentin surface after application of Fit-checker and evaluate the efficiency of various surface treatments in removing the residual silicone film. Materials and Methods: Extracted human molars were mounted on the acrylic block, and the tooth occlusal surface was ground flat till the dentin exposure. All the specimens were assigned into five groups: Group 1: without application of Fit-checker (control group); Group 2: without any surface treatment after peeling off Fit-checker; Group 3: surface treatment with wet pumice; Group 4: 37% phosphoric acid treatment; Group 5: 10% polyacrylic acid treatment. Later, Type 1 Glass Ionomer Cement (GIC) liquid drop was placed on the dentin and photographs were made horizontally using a standardized procedure. Contact angles were measured using AUTOCAD software. Obtained values were statistically analyzed using the One-way ANOVA test and Tukey’s Post hoc test. Samples of each group were examined using the scanning electron microscope. Results: Statistically significant difference was observed among all the groups except between Group 4 and Group 2 (p > 0.05). SEM images of various groups showed a significant difference in roughness patterns. Conclusion: Surface treatment with pumice and the rotary brush was an effective method among the three in cleaning the residual silicone film

    Trichoderma atroviride P1 Colonization of Tomato Plants Enhances Both Direct and Indirect Defense Barriers Against Insects

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    Numerous microbial root symbionts are known to induce different levels of enhanced plant protection against a variety of pathogens. However, more recent studies have demonstrated that beneficial microbes are able to induce plant systemic resistance that confers some degree of protection against insects. Here, we report how treatments with the fungal biocontrol agent Trichoderma atroviride strain P1 in tomato plants induce responses that affect pest insects with different feeding habits: the noctuid moth Spodoptera littoralis (Boisduval) and the aphid Macrosiphum euphorbiae (Thomas). We observed that the tomato plant–Trichoderma P1 interaction had a negative impact on the development of moth larvae and on aphid longevity. These effects were attributed to a plant response induced by Trichoderma that was associated with transcriptional changes of a wide array of defense-related genes. While the impact on aphids could be related to the up-regulation of genes involved in the oxidative burst reaction, which occur early in the defense reaction, the negative performance of moth larvae was associated with the enhanced expression of genes encoding for protective enzymes (i.e., Proteinase inhibitor I (PI), Threonine deaminase, Leucine aminopeptidase A1, Arginase 2, and Polyphenol oxidase) that are activated downstream in the defense cascade. In addition, Trichoderma P1 produced alterations in plant metabolic pathways leading to the production and release of volatile organic compounds (VOCs) that are involved in the attraction of the aphid parasitoid Aphidius ervi, thus reinforcing the indirect plant defense barriers. Our findings, along with the evidence available in the literature, indicate that the outcome of the tripartite interaction among plant, Trichoderma, and pests is highly specific and only a comprehensive approach, integrating both insect phenotypic changes and plant transcriptomic alterations, can allow a reliable prediction of its potential for plant protectio

    Design, synthesis, molecular modelling and in vitro screening of monoamine oxidase inhibitory activities of novel quinazolyl hydrazine derivatives

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    Funding: Deanship of Scientific Research at Taibah University, Al-Madinah Al-Munawarah, Saudi Arabia (project # 7101).A new series of N'-substituted benzylidene-2-(4-oxo-2-phenyl-1,4-dihydroquinazolin-3(2H)-yl)acetohydrazide (5a-5h) has been synthesized, characterized by FT-IR, NMR spectroscopy and mass spectrometry and tested against human monoamine oxidase (MAO) A and B. Only (3-methoxy-4-hydroxy)benzoyl substituted compounds gave submicromolar inhibition of MAO-A and MAO-B. Changing the phenyl substituent to methyl on the unsaturated quinazoline ring (12a-12d) decreased inhibition but a less flexible linker (14a-14d) resulted in selective micromolar inhibition of hMAO B providing insight for ongoing design.Publisher PDFPeer reviewe
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